Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ralRA/- |
Location | 1407813..1408184 | Replicon | chromosome |
Accession | NZ_CP069133 | ||
Organism | Escherichia coli BW25113 substr. CHXR2G20 |
Toxin (Protein)
Gene name | ralR | Uniprot ID | F4VC37 |
Locus tag | JQK31_RS06910 | Protein ID | WP_001317028.1 |
Coordinates | 1407990..1408184 (-) | Length | 65 a.a. |
Antitoxin (RNA)
Gene name | ralA | ||
Locus tag | - | ||
Coordinates | 1407813..1407991 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JQK31_RS06885 | 1403768..1405141 | + | 1374 | WP_000123737.1 | ATP-dependent RNA helicase DbpA | - |
JQK31_RS06890 | 1405270..1406205 | - | 936 | WP_001157406.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
JQK31_RS06895 | 1406257..1407492 | - | 1236 | WP_000040852.1 | site-specific integrase | - |
JQK31_RS06900 | 1407494..1407709 | - | 216 | WP_000079604.1 | excisionase XisR | - |
JQK31_RS06905 | 1407788..1407997 | - | 210 | WP_000276809.1 | double-strand break reduction protein RcbA | - |
- | 1407813..1407991 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1407813..1407991 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1407813..1407991 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 1407813..1407991 | + | 179 | NuclAT_0 | - | Antitoxin |
JQK31_RS06910 | 1407990..1408184 | - | 195 | WP_001317028.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
JQK31_RS06915 | 1408241..1409050 | - | 810 | WP_000166319.1 | recombination protein RecT | - |
JQK31_RS06920 | 1409043..1411643 | - | 2601 | WP_000105143.1 | exodeoxyribonuclease VIII | - |
JQK31_RS06925 | 1411745..1412020 | - | 276 | WP_000632297.1 | protein RacC | - |
JQK31_RS06930 | 1412095..1412265 | - | 171 | WP_001352098.1 | conserved protein, Rac prophage | - |
JQK31_RS06935 | 1412265..1412486 | - | 222 | WP_000560225.1 | killing protein KilR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 1406257..1427931 | 21674 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7018.89 Da Isoelectric Point: 8.9538
>T189956 WP_001317028.1 NZ_CP069133:c1408184-1407990 [Escherichia coli BW25113]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
>T189956 NZ_CP091031:66146-66421 [Escherichia coli]
ATGGAACTGAAGTGGACCAGTAAGGCACTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTGCTGGCCAGTAAACCTGC
TGCCGCCAGAACGGTGCAGTCCCTGACACAGGCGCCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTTCTGGCGAGTACGAAATCCGTTACGAACTTAATGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG
ATGGAACTGAAGTGGACCAGTAAGGCACTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTGCTGGCCAGTAAACCTGC
TGCCGCCAGAACGGTGCAGTCCCTGACACAGGCGCCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTTCTGGCGAGTACGAAATCCGTTACGAACTTAATGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG
Antitoxin
Download Length: 179 bp
>AT189956 NZ_CP069133:1407813-1407991 [Escherichia coli BW25113]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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