Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | IasE-IsrA/SymE(toxin) |
Location | 3547602..3548034 | Replicon | chromosome |
Accession | NZ_CP047535 | ||
Organism | Salmonella enterica subsp. enterica serovar Typhimurium strain SJTUF10452 |
Toxin (Protein)
Gene name | IasE | Uniprot ID | E8XIW0 |
Locus tag | DXN08_RS17690 | Protein ID | WP_000994224.1 |
Coordinates | 3547759..3548034 (+) | Length | 92 a.a. |
Antitoxin (RNA)
Gene name | IsrA | ||
Locus tag | - | ||
Coordinates | 3547602..3548024 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DXN08_RS17660 | 3543820..3544557 | - | 738 | WP_001535430.1 | pili assembly chaperone SafB | - |
DXN08_RS17665 | 3544641..3545153 | - | 513 | WP_077248260.1 | pilus assembly protein | - |
DXN08_RS17670 | 3545903..3546607 | - | 705 | Protein_3458 | integrase core domain-containing protein | - |
DXN08_RS17675 | 3546660..3546908 | + | 249 | WP_001738030.1 | SymE family type I addiction module toxin | - |
DXN08_RS17680 | 3547010..3547318 | - | 309 | WP_010988969.1 | hypothetical protein | - |
DXN08_RS17685 | 3547401..3547574 | - | 174 | WP_088131292.1 | RHS repeat-associated core domain-containing protein | - |
- | 3547602..3548024 | - | 423 | - | - | Antitoxin |
DXN08_RS17690 | 3547759..3548034 | + | 276 | WP_000994224.1 | SymE family type I addiction module toxin | Toxin |
DXN08_RS17695 | 3548087..3548524 | - | 438 | WP_000943619.1 | immunity 26/phosphotriesterase HocA family protein | - |
DXN08_RS17700 | 3549087..3549533 | - | 447 | WP_000935097.1 | protein SciX | - |
DXN08_RS17705 | 3549527..3550396 | - | 870 | Protein_3465 | polymorphic toxin type 47 domain-containing protein | - |
DXN08_RS17710 | 3550460..3550723 | - | 264 | WP_000932531.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Genomic island | - | - | 3536750..3550723 | 13973 | ||
flank | IS/Tn | - | - | 3545903..3546184 | 281 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10032.36 Da Isoelectric Point: 6.4704
>T146473 WP_000994224.1 NZ_CP047535:3547759-3548034 [Salmonella enterica subsp. enterica serovar Typhimurium]
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD
MNASGVSVRHINSETCMTACYSQIPSQHLKGDWQEEAGFETGHGVTVKISEGCLILIAETDEVRDLRKELYQVKKSMKHI
KAGVNNVVNGD
Download Length: 276 bp
>T146473 NZ_CP062752:c4697455-4697141 [Escherichia coli O157:H7]
ATGCAATTTACGGTATACCGCAGTCGCAGTAGGAACGCCGCGTTTCCCTTTGTTATCGATGTTACCAGCGACATTATTGG
TGTGATTAATCGCCGTATTGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA
ATGCAATTTACGGTATACCGCAGTCGCAGTAGGAACGCCGCGTTTCCCTTTGTTATCGATGTTACCAGCGACATTATTGG
TGTGATTAATCGCCGTATTGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA
Antitoxin
Download Length: 423 bp
>AT146473 NZ_CP047535:c3548024-3547602 [Salmonella enterica subsp. enterica serovar Typhimurium]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTGACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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