MGE detailed information

MGE type: Conjugative plasmid        MGE length: 146311 bp
Accession: NZ_OW849065        Location: 1..146311         Organism: Escherichia coli isolate 131       Replicon: plasmid P1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ135_RS25565 (1) 1..858 + 858 WP_000130646.1 incFII family plasmid replication initiator RepA -
LQ135_RS25570 (1797) 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LQ135_RS25575 (2543) 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LQ135_RS25580 (2733) 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LQ135_RS25585 (3271) 3271..6168 - 2898 WP_001553819.1 Tn3 family transposase TnpA_Tn5403 Transposase
LQ135_RS25590 (6263) 6263..6868 + 606 WP_000509965.1 Tn3 family transposase TnpR_Tn5403 Transposase
LQ135_RS25595 (6892) 6892..7641 - 750 Protein_6 Tn3 family transposase TnpA_TnAs1 Transposase
LQ135_RS25600 (7645) 7645..8037 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
LQ135_RS25605 (8175) 8175..9059 + 885 WP_000058717.1 EamA family transporter -
LQ135_RS25610 (9091) 9091..10290 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
LQ135_RS25615 (10396) 10396..11046 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
LQ135_RS25620 (11078) 11078..11320 - 243 WP_032140899.1 hypothetical protein -
LQ135_RS25625 (11362) 11362..12876 - 1515 Protein_12 Tn3 family transposase TnpA_TnAs1 Transposase
LQ135_RS25630 (12942) 12942..13646 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LQ135_RS25635 (13700) 13700..14140 - 441 Protein_14 CatB-related O-acetyltransferase -
LQ135_RS25640 (14278) 14278..15108 - 831 WP_001334766.1 Beta-lactamase OXA-1 ARG
LQ135_RS25645 (15239) 15239..15793 - 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
LQ135_RS25650 (15937) 15937..16641 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LQ135_RS25655 (16718) 16718..18937 - 2220 Protein_18 Tn3 family transposase TnpA_Tn3 Transposase
LQ135_RS25660 (19002) 19002..19295 + 294 WP_116961751.1 WbuC family cupin fold metalloprotein -
LQ135_RS25665 (19342) 19342..20217 - 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
LQ135_RS25670 (20353) 20353..21057 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LQ135_RS25675 (21110) 21110..21277 - 168 Protein_22 recombinase family protein -
LQ135_RS25680 (21403) 21403..21753 - 351 WP_000454193.1 DUF3330 domain-containing protein -
LQ135_RS25685 (21956) 21956..22969 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
LQ135_RS25690 (23127) 23127..23600 + 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
LQ135_RS25695 (23731) 23731..24519 + 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
LQ135_RS25700 (24725) 24725..25072 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
LQ135_RS25705 (25066) 25066..25905 + 840 WP_000259031.1 Dihydropteroate synthase ARG
LQ135_RS25710 (26033) 26033..26533 + 501 WP_000376623.1 GNAT family N-acetyltransferase -
LQ135_RS25715 (26854) 26854..26922 + 69 Protein_30 EAL domain-containing protein -
LQ135_RS25720 (27040) 27040..27804 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
LQ135_RS25725 (27944) 27944..28009 - 66 Protein_32 EAL domain-containing protein -
LQ135_RS25730 (28065) 28065..29279 + 1215 WP_004098817.1 type II site-specific deoxyribonuclease -
LQ135_RS25735 (29313) 29313..30746 - 1434 WP_001288432.1 DNA cytosine methyltransferase -
LQ135_RS25740 (30845) 30845..31117 + 273 Protein_35 IS1 family transposase -
LQ135_RS25745 (31128) 31128..31334 - 207 WP_001749967.1 hypothetical protein -
LQ135_RS25750 (31339) 31339..31986 - 648 WP_015344958.1 restriction endonuclease -
LQ135_RS25755 (32036) 32036..32347 - 312 WP_001452736.1 hypothetical protein -
LQ135_RS25760 (32383) 32383..32697 - 315 WP_001749965.1 TrbM/KikA/MpfK family conjugal transfer protein -
LQ135_RS25765 (32694) 32694..33038 - 345 WP_001749964.1 hypothetical protein -
LQ135_RS25770 (33054) 33054..33359 - 306 WP_000960954.1 H-NS family nucleoid-associated regulatory protein -
LQ135_RS25775 (33468) 33468..34202 + 735 WP_001749963.1 hypothetical protein VF
LQ135_RS25780 (34211) 34211..34492 + 282 WP_000440698.1 transcriptional repressor KorA -
LQ135_RS25785 (34502) 34502..34795 + 294 WP_001749962.1 hypothetical protein -
LQ135_RS25790 (34845) 34845..35162 + 318 WP_000496058.1 hypothetical protein VF
LQ135_RS25795 (35162) 35162..37762 + 2601 WP_001749961.1 Type IV secretion system protein virB4 VF
LQ135_RS25800 (37780) 37780..38493 + 714 WP_001749960.1 Type IV secretion system protein virB5 VF
LQ135_RS25805 (38501) 38501..38728 + 228 WP_001749959.1 IncN-type entry exclusion lipoprotein EexN -
LQ135_RS25810 (38744) 38744..39784 + 1041 WP_001749958.1 type IV secretion system protein -
LQ135_RS25815 (39867) 39867..40013 + 147 WP_001257173.1 hypothetical protein VF
LQ135_RS25820 (40003) 40003..40701 + 699 WP_000646594.1 Type IV secretion system protein virB8 VF
LQ135_RS25825 (40712) 40712..41596 + 885 WP_000735066.1 Type IV secretion system protein virB9 VF
LQ135_RS25830 (41596) 41596..42756 + 1161 WP_000101710.1 Protein virB10 VF
LQ135_RS25835 (42798) 42798..43793 + 996 WP_000128596.1 Type IV secretion system protein VirB11 VF
LQ135_RS25840 (43793) 43793..44038 + 246 Protein_55 hypothetical protein VF
LQ135_RS25845 (44392) 44392..44610 - 219 Protein_56 phospholipase D-like domain-containing protein -
LQ135_RS25850 (44634) 44634..47314 - 2681 Protein_57 Tn3 family transposase ISEc63 Transposase
LQ135_RS25855 (47366) 47366..48070 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LQ135_RS25860 (48095) 48095..49291 + 1197 Protein_59 IS3 family transposase -
LQ135_RS25865 (49373) 49373..49546 + 174 WP_000338295.1 Tn3 family transposase ISPsy39 Transposase
LQ135_RS25870 (49623) 49623..49931 + 309 Protein_61 IS4 family transposase ISEc13 Transposase
LQ135_RS25875 (49990) 49990..51300 - 1311 WP_000476108.1 ABC transporter substrate-binding protein -
LQ135_RS25880 (51293) 51293..52366 - 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
LQ135_RS25885 (52372) 52372..53196 - 825 WP_000922702.1 phosphodiesterase -
LQ135_RS25890 (53207) 53207..54094 - 888 WP_001271561.1 carbohydrate ABC transporter permease -
LQ135_RS25895 (54084) 54084..54962 - 879 WP_000338039.1 sugar ABC transporter permease -
LQ135_RS25900 (55093) 55093..55533 - 441 Protein_67 zinc-binding dehydrogenase -
LQ135_RS25905 (55934) 55934..56824 + 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
LQ135_RS25910 (56849) 56849..57229 + 381 WP_000710783.1 Rid family detoxifying hydrolase -
LQ135_RS25915 (57262) 57262..58227 + 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
LQ135_RS25920 (58273) 58273..59025 - 753 WP_000562172.1 IclR family transcriptional regulator -
LQ135_RS25925 (59630) 59630..59914 + 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
LQ135_RS25930 (59914) 59914..60189 + 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
LQ135_RS25935 (60295) 60295..60498 + 204 Protein_74 hypothetical protein -
LQ135_RS25940 (60623) 60623..60751 - 129 Protein_75 IS481 family transposase -
LQ135_RS25945 (60784) 60784..61953 - 1170 WP_001072355.1 hypothetical protein -
LQ135_RS25950 (62485) 62485..62753 + 269 Protein_77 type II toxin-antitoxin system ParD family antitoxin -
LQ135_RS25955 (62740) 62740..63008 + 269 Protein_78 type II toxin-antitoxin system RelE/ParE family toxin -
LQ135_RS25960 (63042) 63042..63739 + 698 WP_095033700.1 IS1 family transposase IS1R Transposase
LQ135_RS25965 (63993) 63993..65015 - 1023 WP_000361402.1 helicase UvrD -
LQ135_RS25970 (65000) 65000..66565 - 1566 WP_001128474.1 AAA family ATPase -
LQ135_RS25975 (66640) 66640..67056 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LQ135_RS25980 (67053) 67053..67283 - 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
LQ135_RS25985 (67664) 67664..71458 + 3795 WP_001144732.1 hypothetical protein -
LQ135_RS25990 (71503) 71503..71919 - 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LQ135_RS25995 (71916) 71916..72146 - 231 WP_001261278.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
LQ135_RS26000 (72411) 72411..72911 + 501 WP_000528932.1 HEPN family nuclease -
LQ135_RS26005 (72924) 72924..73697 + 774 WP_000905949.1 hypothetical protein -
LQ135_RS26010 (73908) 73908..75521 - 1614 WP_000080195.1 IS66 family transposase ISEc23 Transposase
LQ135_RS26015 (75552) 75552..75902 - 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
LQ135_RS26020 (75899) 75899..76324 - 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
LQ135_RS26025 (76416) 76416..77537 + 1122 WP_012783980.1 DUF3800 domain-containing protein -
LQ135_RS26030 (77571) 77571..78059 - 489 WP_011254646.1 hypothetical protein -
LQ135_RS26035 (78629) 78629..78847 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
LQ135_RS26040 (78849) 78849..79154 + 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
LQ135_RS26045 (79155) 79155..79961 + 807 WP_000016982.1 site-specific integrase -
LQ135_RS26050 (80735) 80735..81490 + 756 WP_000852146.1 replication initiation protein RepE -
LQ135_RS26055 (82078) 82078..83244 + 1167 WP_000772446.1 hypothetical protein VF
LQ135_RS26060 (83244) 83244..84215 + 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
LQ135_RS26065 (85082) 85082..85984 + 903 WP_001348615.1 DUF1281 domain-containing protein -
LQ135_RS26070 (85981) 85981..86292 + 312 WP_011254640.1 hypothetical protein -
LQ135_RS26075 (86369) 86369..87054 + 686 Protein_102 DNA methylase -
LQ135_RS26080 (87055) 87055..87276 + 222 WP_001104873.1 hypothetical protein -
LQ135_RS26085 (87206) 87206..87724 + 519 WP_123325260.1 DUF1380 family protein -
LQ135_RS26090 (87775) 87775..88551 + 777 WP_001753849.1 hypothetical protein -
LQ135_RS26095 (88968) 88968..89393 + 426 WP_001198928.1 antirestriction protein -
LQ135_RS26100 (89440) 89440..89862 + 423 WP_000271753.1 DUF1380 family protein -
LQ135_RS26105 (89859) 89859..90050 + 192 WP_001027516.1 hypothetical protein -
LQ135_RS26110 (91085) 91085..91315 + 231 WP_000218642.1 hypothetical protein -
LQ135_RS26115 (91367) 91367..92728 + 1362 WP_000170728.1 DUF3560 domain-containing protein -
LQ135_RS26120 (92775) 92775..93338 + 564 WP_012783964.1 class I SAM-dependent methyltransferase -
LQ135_RS26125 (93338) 93338..93562 + 225 WP_021538344.1 hypothetical protein -
LQ135_RS26130 (93490) 93490..93732 + 243 WP_001365577.1 hypothetical protein -
LQ135_RS26135 (94854) 94854..96755 + 1902 WP_000936285.1 group II intron reverse transcriptase/maturase -
LQ135_RS26140 (96905) 96905..97390 + 486 WP_042029316.1 single-stranded DNA-binding protein -
LQ135_RS26145 (97446) 97446..97679 + 234 WP_000006004.1 DUF905 domain-containing protein -
LQ135_RS26150 (97738) 97738..99696 + 1959 WP_200121858.1 ParB/RepB/Spo0J family partition protein -
LQ135_RS26155 (99751) 99751..100185 + 435 WP_000845901.1 conjugation system SOS inhibitor PsiB -
LQ135_RS26160 (100182) 100182..100944 + 763 Protein_119 plasmid SOS inhibition protein A -
LQ135_RS26165 (100913) 100913..101101 - 189 WP_001299721.1 hypothetical protein -
- (100913) 100913..101137 + 225 NuclAT_0 - -
- (100913) 100913..101137 + 225 NuclAT_0 - -
- (100913) 100913..101137 + 225 NuclAT_0 - -
- (100913) 100913..101137 + 225 NuclAT_0 - -
LQ135_RS26170 (101123) 101123..101272 + 150 Protein_121 plasmid maintenance protein Mok -
LQ135_RS26175 (101214) 101214..101339 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
LQ135_RS26180 (101559) 101559..101789 + 231 WP_071587244.1 hypothetical protein -
LQ135_RS26185 (101787) 101787..101960 - 174 Protein_124 hypothetical protein -
LQ135_RS26190 (102258) 102258..102545 + 288 WP_000107537.1 hypothetical protein -
LQ135_RS26195 (102666) 102666..103487 + 822 WP_001234469.1 DUF932 domain-containing protein -
LQ135_RS26200 (103784) 103784..104431 - 648 WP_000614282.1 hypothetical protein VF
LQ135_RS26205 (104717) 104717..105100 + 384 WP_001151564.1 conjugal transfer relaxosome DNA-binding protein TraM -
LQ135_RS26210 (105294) 105294..105980 + 687 WP_000332487.1 PAS domain-containing protein -
LQ135_RS26215 (106074) 106074..106301 + 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
LQ135_RS26220 (106335) 106335..106697 + 363 WP_001098998.1 type IV conjugative transfer system pilin TraA -
LQ135_RS26225 (106702) 106702..107013 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
LQ135_RS26230 (107035) 107035..107601 + 567 WP_000399804.1 type IV conjugative transfer system protein TraE -
LQ135_RS26235 (107588) 107588..108316 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
LQ135_RS26240 (108316) 108316..109743 + 1428 WP_000146638.1 F-type conjugal transfer pilus assembly protein TraB -
LQ135_RS26245 (109733) 109733..110317 + 585 WP_000002795.1 conjugal transfer pilus-stabilizing protein TraP -
LQ135_RS26250 (110304) 110304..110624 + 321 WP_001057302.1 conjugal transfer protein TrbD -
LQ135_RS26255 (110617) 110617..110868 + 252 WP_001038341.1 conjugal transfer protein TrbG -
LQ135_RS26260 (110865) 110865..111380 + 516 WP_000809893.1 type IV conjugative transfer system lipoprotein TraV -
LQ135_RS26265 (111515) 111515..111736 + 222 WP_001278978.1 conjugal transfer protein TraR -
LQ135_RS26270 (111896) 111896..114526 + 2631 WP_012783967.1 type IV secretion system protein TraC -
LQ135_RS26275 (114573) 114573..115277 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LQ135_RS26280 (115521) 115521..116783 - 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
LQ135_RS26285 (116855) 116855..117559 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LQ135_RS26290 (117652) 117652..118644 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
LQ135_RS26295 (118674) 118674..118979 + 306 WP_000224416.1 hypothetical protein -
LQ135_RS26300 (118988) 118988..119626 + 639 WP_001080256.1 type-F conjugative transfer system pilin assembly protein TrbC -
LQ135_RS26305 (119623) 119623..121473 + 1851 WP_000821856.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
LQ135_RS26310 (121500) 121500..121757 + 258 WP_000864353.1 conjugal transfer protein TrbE -
LQ135_RS26315 (121750) 121750..122493 + 744 WP_001030371.1 type-F conjugative transfer system pilin assembly protein TraF -
LQ135_RS26320 (122507) 122507..122851 + 345 WP_000556796.1 conjugal transfer protein TrbA -
LQ135_RS26325 (122970) 122970..123254 + 285 WP_000624194.1 type-F conjugative transfer system pilin chaperone TraQ -
LQ135_RS26330 (123241) 123241..123786 + 546 WP_000059831.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LQ135_RS26335 (123716) 123716..124063 + 348 WP_001309242.1 P-type conjugative transfer protein TrbJ -
LQ135_RS26340 (124044) 124044..124436 + 393 WP_000660699.1 F-type conjugal transfer protein TrbF -
LQ135_RS26345 (124423) 124423..125796 + 1374 WP_000944331.1 conjugal transfer pilus assembly protein TraH -
LQ135_RS26350 (125793) 125793..128615 + 2823 WP_001007039.1 conjugal transfer mating-pair stabilization protein TraG -
LQ135_RS26355 (128631) 128631..129116 + 486 WP_000605870.1 hypothetical protein -
LQ135_RS26360 (129165) 129165..129896 + 732 WP_000782451.1 conjugal transfer complement resistance protein TraT -
LQ135_RS26365 (130099) 130099..130836 + 738 WP_000199905.1 hypothetical protein -
LQ135_RS26370 (130887) 130887..131420 + 534 Protein_161 TraD N-terminal domain-containing protein -
LQ135_RS26375 (131613) 131613..133154 + 1542 WP_001298859.1 IS21 family transposase ISEc12 Transposase
LQ135_RS26380 (133169) 133169..133915 + 747 WP_001016257.1 IS21 family transposase ISEc12 Transposase
LQ135_RS26385 (134001) 134001..135707 + 1707 Protein_164 type IV conjugative transfer system coupling protein TraD -
LQ135_RS26390 (135707) 135707..140977 + 5271 WP_000948354.1 Multifunctional conjugation protein TraI Relaxase
LQ135_RS26395 (140997) 140997..141743 + 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
LQ135_RS26400 (141802) 141802..142662 + 861 WP_000704523.1 Quorum-quenching protein AidA VF
LQ135_RS26405 (142765) 142765..143325 + 561 WP_000139321.1 fertility inhibition protein FinO -
LQ135_RS26410 (143427) 143427..144124 + 698 WP_095033700.1 IS1 family transposase IS1R Transposase
LQ135_RS26415 (144169) 144169..144630 + 462 WP_001233838.1 thermonuclease family protein -
LQ135_RS26420 (144676) 144676..144885 + 210 WP_001298565.1 hemolysin expression modulator Hha -
LQ135_RS26425 (144923) 144923..145513 + 591 WP_000766807.1 DUF2726 domain-containing protein -
LQ135_RS26430 (145753) 145753..146007 + 255 WP_000083830.1 replication regulatory protein RepA -
LQ135_RS26435 (146114) 146114..146299 + 186 WP_012615301.1 plasmid copy control protein CopA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance