MGE detailed information
MGE type: Conjugative plasmid MGE length: 146311 bp
Accession: NZ_OW849065 Location: 1..146311 Organism: Escherichia coli isolate 131 Replicon: plasmid P1
Accession: NZ_OW849065 Location: 1..146311 Organism: Escherichia coli isolate 131 Replicon: plasmid P1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LQ135_RS25565 () | 1..858 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| LQ135_RS25570 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LQ135_RS25575 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LQ135_RS25580 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LQ135_RS25585 () | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| LQ135_RS25590 () | 6263..6868 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| LQ135_RS25595 () | 6892..7641 | - | 750 | Protein_6 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LQ135_RS25600 () | 7645..8037 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| LQ135_RS25605 () | 8175..9059 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| LQ135_RS25610 () | 9091..10290 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| LQ135_RS25615 () | 10396..11046 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LQ135_RS25620 () | 11078..11320 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| LQ135_RS25625 () | 11362..12876 | - | 1515 | Protein_12 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LQ135_RS25630 () | 12942..13646 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LQ135_RS25635 () | 13700..14140 | - | 441 | Protein_14 | CatB-related O-acetyltransferase | - |
| LQ135_RS25640 () | 14278..15108 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| LQ135_RS25645 () | 15239..15793 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| LQ135_RS25650 () | 15937..16641 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LQ135_RS25655 () | 16718..18937 | - | 2220 | Protein_18 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LQ135_RS25660 () | 19002..19295 | + | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| LQ135_RS25665 () | 19342..20217 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| LQ135_RS25670 () | 20353..21057 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LQ135_RS25675 () | 21110..21277 | - | 168 | Protein_22 | recombinase family protein | - |
| LQ135_RS25680 () | 21403..21753 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| LQ135_RS25685 () | 21956..22969 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| LQ135_RS25690 () | 23127..23600 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| LQ135_RS25695 () | 23731..24519 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| LQ135_RS25700 () | 24725..25072 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| LQ135_RS25705 () | 25066..25905 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LQ135_RS25710 () | 26033..26533 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| LQ135_RS25715 () | 26854..26922 | + | 69 | Protein_30 | EAL domain-containing protein | - |
| LQ135_RS25720 () | 27040..27804 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| LQ135_RS25725 () | 27944..28009 | - | 66 | Protein_32 | EAL domain-containing protein | - |
| LQ135_RS25730 () | 28065..29279 | + | 1215 | WP_004098817.1 | type II site-specific deoxyribonuclease | - |
| LQ135_RS25735 () | 29313..30746 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| LQ135_RS25740 () | 30845..31117 | + | 273 | Protein_35 | IS1 family transposase | - |
| LQ135_RS25745 () | 31128..31334 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| LQ135_RS25750 () | 31339..31986 | - | 648 | WP_015344958.1 | restriction endonuclease | - |
| LQ135_RS25755 () | 32036..32347 | - | 312 | WP_001452736.1 | hypothetical protein | - |
| LQ135_RS25760 () | 32383..32697 | - | 315 | WP_001749965.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| LQ135_RS25765 () | 32694..33038 | - | 345 | WP_001749964.1 | hypothetical protein | - |
| LQ135_RS25770 () | 33054..33359 | - | 306 | WP_000960954.1 | H-NS family nucleoid-associated regulatory protein | - |
| LQ135_RS25775 () | 33468..34202 | + | 735 | WP_001749963.1 | hypothetical protein | VF |
| LQ135_RS25780 () | 34211..34492 | + | 282 | WP_000440698.1 | transcriptional repressor KorA | - |
| LQ135_RS25785 () | 34502..34795 | + | 294 | WP_001749962.1 | hypothetical protein | - |
| LQ135_RS25790 () | 34845..35162 | + | 318 | WP_000496058.1 | hypothetical protein | VF |
| LQ135_RS25795 () | 35162..37762 | + | 2601 | WP_001749961.1 | Type IV secretion system protein virB4 | VF |
| LQ135_RS25800 () | 37780..38493 | + | 714 | WP_001749960.1 | Type IV secretion system protein virB5 | VF |
| LQ135_RS25805 () | 38501..38728 | + | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| LQ135_RS25810 () | 38744..39784 | + | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| LQ135_RS25815 () | 39867..40013 | + | 147 | WP_001257173.1 | hypothetical protein | VF |
| LQ135_RS25820 () | 40003..40701 | + | 699 | WP_000646594.1 | Type IV secretion system protein virB8 | VF |
| LQ135_RS25825 () | 40712..41596 | + | 885 | WP_000735066.1 | Type IV secretion system protein virB9 | VF |
| LQ135_RS25830 () | 41596..42756 | + | 1161 | WP_000101710.1 | Protein virB10 | VF |
| LQ135_RS25835 () | 42798..43793 | + | 996 | WP_000128596.1 | Type IV secretion system protein VirB11 | VF |
| LQ135_RS25840 () | 43793..44038 | + | 246 | Protein_55 | hypothetical protein | VF |
| LQ135_RS25845 () | 44392..44610 | - | 219 | Protein_56 | phospholipase D-like domain-containing protein | - |
| LQ135_RS25850 () | 44634..47314 | - | 2681 | Protein_57 | Tn3 family transposase ISEc63 | Transposase |
| LQ135_RS25855 () | 47366..48070 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LQ135_RS25860 () | 48095..49291 | + | 1197 | Protein_59 | IS3 family transposase | - |
| LQ135_RS25865 () | 49373..49546 | + | 174 | WP_000338295.1 | Tn3 family transposase ISPsy39 | Transposase |
| LQ135_RS25870 () | 49623..49931 | + | 309 | Protein_61 | IS4 family transposase ISEc13 | Transposase |
| LQ135_RS25875 () | 49990..51300 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| LQ135_RS25880 () | 51293..52366 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| LQ135_RS25885 () | 52372..53196 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| LQ135_RS25890 () | 53207..54094 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| LQ135_RS25895 () | 54084..54962 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| LQ135_RS25900 () | 55093..55533 | - | 441 | Protein_67 | zinc-binding dehydrogenase | - |
| LQ135_RS25905 () | 55934..56824 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| LQ135_RS25910 () | 56849..57229 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| LQ135_RS25915 () | 57262..58227 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| LQ135_RS25920 () | 58273..59025 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| LQ135_RS25925 () | 59630..59914 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| LQ135_RS25930 () | 59914..60189 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| LQ135_RS25935 () | 60295..60498 | + | 204 | Protein_74 | hypothetical protein | - |
| LQ135_RS25940 () | 60623..60751 | - | 129 | Protein_75 | IS481 family transposase | - |
| LQ135_RS25945 () | 60784..61953 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| LQ135_RS25950 () | 62485..62753 | + | 269 | Protein_77 | type II toxin-antitoxin system ParD family antitoxin | - |
| LQ135_RS25955 () | 62740..63008 | + | 269 | Protein_78 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LQ135_RS25960 () | 63042..63739 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| LQ135_RS25965 () | 63993..65015 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| LQ135_RS25970 () | 65000..66565 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| LQ135_RS25975 () | 66640..67056 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| LQ135_RS25980 () | 67053..67283 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| LQ135_RS25985 () | 67664..71458 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| LQ135_RS25990 () | 71503..71919 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| LQ135_RS25995 () | 71916..72146 | - | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| LQ135_RS26000 () | 72411..72911 | + | 501 | WP_000528932.1 | HEPN family nuclease | - |
| LQ135_RS26005 () | 72924..73697 | + | 774 | WP_000905949.1 | hypothetical protein | - |
| LQ135_RS26010 () | 73908..75521 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| LQ135_RS26015 () | 75552..75902 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| LQ135_RS26020 () | 75899..76324 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| LQ135_RS26025 () | 76416..77537 | + | 1122 | WP_012783980.1 | DUF3800 domain-containing protein | - |
| LQ135_RS26030 () | 77571..78059 | - | 489 | WP_011254646.1 | hypothetical protein | - |
| LQ135_RS26035 () | 78629..78847 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LQ135_RS26040 () | 78849..79154 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LQ135_RS26045 () | 79155..79961 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| LQ135_RS26050 () | 80735..81490 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| LQ135_RS26055 () | 82078..83244 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| LQ135_RS26060 () | 83244..84215 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| LQ135_RS26065 () | 85082..85984 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| LQ135_RS26070 () | 85981..86292 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| LQ135_RS26075 () | 86369..87054 | + | 686 | Protein_102 | DNA methylase | - |
| LQ135_RS26080 () | 87055..87276 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| LQ135_RS26085 () | 87206..87724 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| LQ135_RS26090 () | 87775..88551 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| LQ135_RS26095 () | 88968..89393 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| LQ135_RS26100 () | 89440..89862 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| LQ135_RS26105 () | 89859..90050 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| LQ135_RS26110 () | 91085..91315 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| LQ135_RS26115 () | 91367..92728 | + | 1362 | WP_000170728.1 | DUF3560 domain-containing protein | - |
| LQ135_RS26120 () | 92775..93338 | + | 564 | WP_012783964.1 | class I SAM-dependent methyltransferase | - |
| LQ135_RS26125 () | 93338..93562 | + | 225 | WP_021538344.1 | hypothetical protein | - |
| LQ135_RS26130 () | 93490..93732 | + | 243 | WP_001365577.1 | hypothetical protein | - |
| LQ135_RS26135 () | 94854..96755 | + | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| LQ135_RS26140 () | 96905..97390 | + | 486 | WP_042029316.1 | single-stranded DNA-binding protein | - |
| LQ135_RS26145 () | 97446..97679 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| LQ135_RS26150 () | 97738..99696 | + | 1959 | WP_200121858.1 | ParB/RepB/Spo0J family partition protein | - |
| LQ135_RS26155 () | 99751..100185 | + | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| LQ135_RS26160 () | 100182..100944 | + | 763 | Protein_119 | plasmid SOS inhibition protein A | - |
| LQ135_RS26165 () | 100913..101101 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 100913..101137 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 100913..101137 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 100913..101137 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 100913..101137 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - | 101070..101135 | - | 66 | - | - | Antitoxin Detail |
| LQ135_RS26170 () | 101123..101272 | + | 150 | Protein_121 | plasmid maintenance protein Mok | - |
| LQ135_RS26175 () | 101214..101339 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| LQ135_RS26180 () | 101559..101789 | + | 231 | WP_071587244.1 | hypothetical protein | - |
| LQ135_RS26185 () | 101787..101960 | - | 174 | Protein_124 | hypothetical protein | - |
| LQ135_RS26190 () | 102258..102545 | + | 288 | WP_000107537.1 | hypothetical protein | - |
| LQ135_RS26195 () | 102666..103487 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| LQ135_RS26200 () | 103784..104431 | - | 648 | WP_000614282.1 | hypothetical protein | VF |
| LQ135_RS26205 () | 104717..105100 | + | 384 | WP_001151564.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LQ135_RS26210 () | 105294..105980 | + | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| LQ135_RS26215 () | 106074..106301 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| LQ135_RS26220 () | 106335..106697 | + | 363 | WP_001098998.1 | type IV conjugative transfer system pilin TraA | - |
| LQ135_RS26225 () | 106702..107013 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| LQ135_RS26230 () | 107035..107601 | + | 567 | WP_000399804.1 | type IV conjugative transfer system protein TraE | - |
| LQ135_RS26235 () | 107588..108316 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| LQ135_RS26240 () | 108316..109743 | + | 1428 | WP_000146638.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LQ135_RS26245 () | 109733..110317 | + | 585 | WP_000002795.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| LQ135_RS26250 () | 110304..110624 | + | 321 | WP_001057302.1 | conjugal transfer protein TrbD | - |
| LQ135_RS26255 () | 110617..110868 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| LQ135_RS26260 () | 110865..111380 | + | 516 | WP_000809893.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LQ135_RS26265 () | 111515..111736 | + | 222 | WP_001278978.1 | conjugal transfer protein TraR | - |
| LQ135_RS26270 () | 111896..114526 | + | 2631 | WP_012783967.1 | type IV secretion system protein TraC | - |
| LQ135_RS26275 () | 114573..115277 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LQ135_RS26280 () | 115521..116783 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| LQ135_RS26285 () | 116855..117559 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LQ135_RS26290 () | 117652..118644 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| LQ135_RS26295 () | 118674..118979 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| LQ135_RS26300 () | 118988..119626 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LQ135_RS26305 () | 119623..121473 | + | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LQ135_RS26310 () | 121500..121757 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| LQ135_RS26315 () | 121750..122493 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LQ135_RS26320 () | 122507..122851 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| LQ135_RS26325 () | 122970..123254 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LQ135_RS26330 () | 123241..123786 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LQ135_RS26335 () | 123716..124063 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| LQ135_RS26340 () | 124044..124436 | + | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| LQ135_RS26345 () | 124423..125796 | + | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| LQ135_RS26350 () | 125793..128615 | + | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LQ135_RS26355 () | 128631..129116 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| LQ135_RS26360 () | 129165..129896 | + | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| LQ135_RS26365 () | 130099..130836 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| LQ135_RS26370 () | 130887..131420 | + | 534 | Protein_161 | TraD N-terminal domain-containing protein | - |
| LQ135_RS26375 () | 131613..133154 | + | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| LQ135_RS26380 () | 133169..133915 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| LQ135_RS26385 () | 134001..135707 | + | 1707 | Protein_164 | type IV conjugative transfer system coupling protein TraD | - |
| LQ135_RS26390 () | 135707..140977 | + | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| LQ135_RS26395 () | 140997..141743 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| LQ135_RS26400 () | 141802..142662 | + | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| LQ135_RS26405 () | 142765..143325 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| LQ135_RS26410 () | 143427..144124 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| LQ135_RS26415 () | 144169..144630 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| LQ135_RS26420 () | 144676..144885 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| LQ135_RS26425 () | 144923..145513 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| LQ135_RS26430 () | 145753..146007 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| LQ135_RS26435 () | 146114..146299 | + | 186 | WP_012615301.1 | plasmid copy control protein CopA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|