MGE detailed information
MGE type: Conjugative plasmid MGE length: 155857 bp
Accession: NZ_CP126953 Location: 1..155857 Organism: Escherichia coli O78:H4 strain APEC E12049 Replicon: plasmid pEND_Eco 12049-1
Accession: NZ_CP126953 Location: 1..155857 Organism: Escherichia coli O78:H4 strain APEC E12049 Replicon: plasmid pEND_Eco 12049-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQA22_RS25160 (1) | 1..639 | + | 639 | WP_000777688.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| QQA22_RS25165 (636) | 636..2444 | + | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| QQA22_RS25170 (2471) | 2471..2728 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| QQA22_RS25175 (2721) | 2721..3464 | + | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| QQA22_RS25180 (3480) | 3480..3827 | + | 348 | WP_001287907.1 | conjugal transfer protein TrbA | - |
| QQA22_RS25185 (3829) | 3829..4104 | - | 276 | WP_001513501.1 | hypothetical protein | - |
| QQA22_RS25190 (4350) | 4350..5891 | + | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| QQA22_RS25195 (5906) | 5906..6652 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| QQA22_RS25200 (6855) | 6855..7139 | + | 285 | WP_000624108.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| QQA22_RS25205 (7126) | 7126..7671 | + | 546 | WP_000059833.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| QQA22_RS25210 (7601) | 7601..7942 | + | 342 | WP_001442101.1 | P-type conjugative transfer protein TrbJ | - |
| QQA22_RS25215 (7929) | 7929..8321 | + | 393 | Protein_11 | F-type conjugal transfer protein TrbF | - |
| QQA22_RS25220 (8308) | 8308..9681 | + | 1374 | WP_000944319.1 | conjugal transfer pilus assembly protein TraH | - |
| QQA22_RS25225 (9678) | 9678..12503 | + | 2826 | WP_001007037.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| QQA22_RS25230 (12500) | 12500..13009 | + | 510 | WP_000628107.1 | conjugal transfer entry exclusion protein TraS | - |
| QQA22_RS25235 (13023) | 13023..13754 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| QQA22_RS25240 (14007) | 14007..16160 | + | 2154 | WP_000009325.1 | type IV conjugative transfer system coupling protein TraD | - |
| QQA22_RS25245 (16169) | 16169..16567 | - | 399 | WP_000911333.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| QQA22_RS25250 (16567) | 16567..16794 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| QQA22_RS25255 (16876) | 16876..22146 | + | 5271 | WP_289245672.1 | Multifunctional conjugation protein TraI | Relaxase |
| QQA22_RS25260 (22166) | 22166..22912 | + | 747 | WP_039005755.1 | conjugal transfer pilus acetylase TraX | - |
| QQA22_RS25265 (22967) | 22967..23527 | + | 561 | WP_039005753.1 | fertility inhibition protein FinO | - |
| QQA22_RS25270 (23663) | 23663..23875 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| QQA22_RS25275 (24085) | 24085..25656 | - | 1572 | WP_113255196.1 | IS66 family transposase ISCro1 | Transposase |
| QQA22_RS25280 (25676) | 25676..26023 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| QQA22_RS25285 (26023) | 26023..26700 | - | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| QQA22_RS25290 (26828) | 26828..26902 | + | 75 | Protein_26 | endonuclease | - |
| - (27158) | 27158..27219 | - | 62 | NuclAT_1 | - | - |
| - (27158) | 27158..27219 | - | 62 | NuclAT_1 | - | - |
| - (27158) | 27158..27219 | - | 62 | NuclAT_1 | - | - |
| - (27158) | 27158..27219 | - | 62 | NuclAT_1 | - | - |
| QQA22_RS25295 (27263) | 27263..27412 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| QQA22_RS25300 (27696) | 27696..27953 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| QQA22_RS25305 (27970) | 27970..28221 | - | 252 | WP_223195197.1 | replication protein RepA | - |
| QQA22_RS25310 (28212) | 28212..28259 | + | 48 | WP_229471593.1 | hypothetical protein | - |
| QQA22_RS25315 (28252) | 28252..28734 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| QQA22_RS25320 (28727) | 28727..29584 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| QQA22_RS25325 (30547) | 30547..30798 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| QQA22_RS25330 (30795) | 30795..31082 | + | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| QQA22_RS25340 (32833) | 32833..36966 | + | 4134 | WP_001080138.1 | Hemoglobin-binding protease hbp autotransporter | VF |
| QQA22_RS25345 (37078) | 37078..37454 | + | 377 | Protein_37 | IS1-like element IS1A family transposase | - |
| QQA22_RS25350 (37493) | 37493..39031 | - | 1539 | WP_000997962.1 | IS66 family transposase ISEc8 | Transposase |
| QQA22_RS25355 (39081) | 39081..39428 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| QQA22_RS25360 (39425) | 39425..39805 | - | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| QQA22_RS25365 (39899) | 39899..40225 | + | 327 | Protein_41 | IS1 family transposase IS1S | Transposase |
| QQA22_RS25370 (40405) | 40405..40918 | - | 514 | Protein_42 | DUF4113 domain-containing protein | - |
| QQA22_RS25375 (40979) | 40979..41083 | - | 105 | Protein_43 | AAA family ATPase | - |
| QQA22_RS25380 (41085) | 41085..41408 | - | 324 | Protein_44 | IS21 family transposase IS21 | Transposase |
| QQA22_RS25385 (42152) | 42152..43129 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| QQA22_RS25390 (43415) | 43415..44155 | - | 741 | WP_001603634.1 | tyrosine-type recombinase/integrase | - |
| QQA22_RS25395 (44276) | 44276..44464 | - | 189 | WP_032145890.1 | hypothetical protein | - |
| QQA22_RS25400 (44838) | 44838..45740 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| QQA22_RS25405 (45809) | 45809..46918 | - | 1110 | WP_001696610.1 | SDR family oxidoreductase | - |
| QQA22_RS25410 (47350) | 47350..48303 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| QQA22_RS25415 (49556) | 49556..50096 | - | 541 | Protein_51 | IS3 family transposase IS1351 | Transposase |
| QQA22_RS25420 (51707) | 51707..52894 | + | 1188 | WP_001696612.1 | efflux RND transporter periplasmic adaptor subunit | - |
| QQA22_RS25425 (52891) | 52891..54831 | + | 1941 | WP_001610286.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| QQA22_RS25430 (54835) | 54835..56205 | + | 1371 | WP_001696614.1 | efflux transporter outer membrane subunit | - |
| QQA22_RS25435 (56536) | 56536..57849 | + | 1314 | Protein_55 | IS4 family transposase | - |
| QQA22_RS25440 (58589) | 58589..59377 | + | 789 | WP_001696616.1 | hypothetical protein | - |
| QQA22_RS25445 (59379) | 59379..61643 | + | 2265 | WP_001610298.1 | UvrD-helicase domain-containing protein | - |
| QQA22_RS25450 (61894) | 61894..61998 | + | 105 | Protein_58 | IS3 family transposase IS1351 | Transposase |
| QQA22_RS25455 (62404) | 62404..63749 | - | 1346 | Protein_59 | ISNCY family transposase ISLad2 | Transposase |
| QQA22_RS25460 (63985) | 63985..64356 | - | 372 | WP_001610302.1 | hypothetical protein | - |
| QQA22_RS25465 (64399) | 64399..64866 | - | 468 | WP_001610303.1 | hypothetical protein | - |
| QQA22_RS25470 (64866) | 64866..65135 | - | 270 | WP_001610304.1 | hypothetical protein | - |
| QQA22_RS25475 (65367) | 65367..66764 | - | 1398 | WP_039005764.1 | ISNCY family transposase ISKpn21 | Transposase |
| QQA22_RS25480 (67072) | 67072..67221 | - | 150 | Protein_64 | IS3 family transposase IS2 | Transposase |
| QQA22_RS25485 (67399) | 67399..68592 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| QQA22_RS25495 (71686) | 71686..71979 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| QQA22_RS25500 (72037) | 72037..72236 | - | 200 | Protein_68 | lysis protein | - |
| QQA22_RS25505 (72790) | 72790..73819 | + | 1030 | Protein_69 | IS481 family transposase ISKpn28 | Transposase |
| QQA22_RS25510 (75130) | 75130..76245 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| QQA22_RS25515 (76385) | 76385..80044 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| QQA22_RS25520 (80148) | 80148..81377 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| QQA22_RS25525 (81462) | 81462..82418 | + | 957 | WP_000271276.1 | hypothetical protein | VF |
| QQA22_RS25530 (82463) | 82463..84640 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| QQA22_RS25535 (85494) | 85494..85628 | - | 135 | WP_249531455.1 | hypothetical protein | - |
| QQA22_RS25540 (85588) | 85588..86529 | - | 942 | WP_039005283.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| QQA22_RS25545 (86710) | 86710..87010 | + | 301 | Protein_77 | hypothetical protein | - |
| QQA22_RS25550 (87088) | 87088..87435 | - | 348 | WP_000142437.1 | DUF6404 family protein | - |
| QQA22_RS25555 (87737) | 87737..88219 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| QQA22_RS25560 (88336) | 88336..89184 | - | 849 | WP_001058005.1 | 3'-5' exonuclease | - |
| QQA22_RS25565 (89230) | 89230..89508 | - | 279 | WP_097309154.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| QQA22_RS25570 (89508) | 89508..89777 | - | 270 | WP_000079941.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| QQA22_RS25575 (90299) | 90299..91527 | + | 1229 | WP_289245670.1 | IS3 family transposase IS2 | Transposase |
| QQA22_RS25580 (91724) | 91724..92998 | + | 1275 | WP_000489607.1 | HlyD family secretion protein | - |
| QQA22_RS25585 (93105) | 93105..93377 | + | 273 | Protein_85 | IS4 family transposase IS421 | Transposase |
| QQA22_RS25590 (93558) | 93558..94544 | + | 987 | Protein_86 | IS4 family transposase IS421 | Transposase |
| QQA22_RS25595 (95168) | 95168..95371 | - | 204 | Protein_87 | hypothetical protein | - |
| QQA22_RS25600 (95544) | 95544..95711 | + | 168 | Protein_88 | colicin-B | - |
| QQA22_RS25605 (95729) | 95729..96256 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| QQA22_RS25610 (96500) | 96500..97315 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| QQA22_RS25615 (97365) | 97365..97718 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| QQA22_RS25620 (97896) | 97896..98687 | - | 792 | WP_000016494.1 | site-specific integrase | - |
| QQA22_RS25625 (98684) | 98684..99373 | - | 690 | WP_000796229.1 | hypothetical protein | - |
| QQA22_RS25630 (99417) | 99417..99767 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| QQA22_RS25635 (100371) | 100371..100601 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| QQA22_RS25640 (100598) | 100598..101014 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| QQA22_RS25645 (101089) | 101089..102654 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| QQA22_RS25650 (102639) | 102639..103661 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| QQA22_RS25660 (104739) | 104739..105653 | + | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| QQA22_RS25665 (105653) | 105653..106480 | + | 828 | WP_000983712.1 | Manganese transport system ATP-binding protein MntB | VF |
| QQA22_RS25670 (106477) | 106477..107334 | + | 858 | WP_021566159.1 | Manganese transport system membrane protein MntB | ARG |
| QQA22_RS25675 (107331) | 107331..108188 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| QQA22_RS25680 (108422) | 108422..108679 | - | 258 | Protein_104 | Tn3 family transposase | - |
| QQA22_RS25685 (108677) | 108677..109090 | + | 414 | Protein_105 | phosphopyruvate hydratase | - |
| QQA22_RS25690 (109431) | 109431..109811 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| QQA22_RS25695 (110191) | 110191..111384 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| QQA22_RS25700 (111520) | 111520..113244 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| QQA22_RS25705 (113245) | 113245..114192 | + | 948 | WP_000011907.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| QQA22_RS25710 (114192) | 114192..115934 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| QQA22_RS25715 (115931) | 115931..117264 | + | 1334 | Protein_111 | L-lysine N6-monooxygenase | VF |
| QQA22_RS25720 (117290) | 117290..119491 | + | 2202 | WP_000973517.1 | Ferric aerobactin receptor | VF |
| QQA22_RS25725 (120016) | 120016..120713 | + | 698 | WP_223155668.1 | IS1 family transposase IS1A | Transposase |
| QQA22_RS25730 (120724) | 120724..121386 | - | 663 | WP_000163251.1 | hypothetical protein | - |
| QQA22_RS25735 (121826) | 121826..122305 | - | 480 | WP_000190054.1 | hypothetical protein | - |
| QQA22_RS25740 (122447) | 122447..122872 | + | 426 | WP_012300440.1 | hypothetical protein | - |
| QQA22_RS25745 (123489) | 123489..124991 | + | 1503 | WP_000715078.1 | hypothetical protein | - |
| QQA22_RS25750 (125241) | 125241..125408 | + | 168 | WP_000638861.1 | hypothetical protein | - |
| QQA22_RS25755 (125505) | 125505..126202 | + | 698 | WP_225343802.1 | IS1 family transposase IS1S | Transposase |
| QQA22_RS25760 (126502) | 126502..127668 | + | 1167 | WP_001238646.1 | hypothetical protein | VF |
| QQA22_RS25765 (127668) | 127668..128639 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| QQA22_RS25770 (129276) | 129276..129445 | + | 170 | Protein_122 | hypothetical protein | - |
| QQA22_RS25775 (129638) | 129638..130750 | - | 1113 | WP_021513474.1 | IS4 family transposase IS421 | Transposase |
| QQA22_RS25780 (130893) | 130893..131318 | + | 426 | WP_001198922.1 | antirestriction protein | - |
| QQA22_RS25785 (131318) | 131318..131779 | + | 462 | WP_042007484.1 | DUF1380 family protein | - |
| QQA22_RS25790 (131779) | 131779..131961 | + | 183 | WP_001027505.1 | hypothetical protein | - |
| QQA22_RS25795 (132185) | 132185..132438 | - | 254 | Protein_127 | hypothetical protein | - |
| QQA22_RS25800 (132955) | 132955..133185 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| QQA22_RS25805 (133237) | 133237..134598 | + | 1362 | WP_000170649.1 | DUF3560 domain-containing protein | - |
| QQA22_RS25810 (134646) | 134646..135209 | + | 564 | WP_001332335.1 | class I SAM-dependent methyltransferase | - |
| QQA22_RS25815 (135206) | 135206..135469 | + | 264 | WP_244566452.1 | hypothetical protein | - |
| QQA22_RS25820 (135361) | 135361..135639 | + | 279 | WP_072127934.1 | hypothetical protein | - |
| QQA22_RS25825 (136112) | 136112..136639 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| QQA22_RS25830 (136695) | 136695..136928 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| QQA22_RS25835 (136987) | 136987..138945 | + | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| QQA22_RS25840 (139000) | 139000..139434 | + | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| QQA22_RS25845 (139431) | 139431..140193 | + | 763 | Protein_137 | plasmid SOS inhibition protein A | - |
| QQA22_RS25850 (140162) | 140162..140350 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (140162) | 140162..140386 | + | 225 | NuclAT_0 | - | - |
| - (140162) | 140162..140386 | + | 225 | NuclAT_0 | - | - |
| - (140162) | 140162..140386 | + | 225 | NuclAT_0 | - | - |
| - (140162) | 140162..140386 | + | 225 | NuclAT_0 | - | - |
| QQA22_RS25855 (140372) | 140372..140521 | + | 150 | Protein_139 | plasmid maintenance protein Mok | - |
| QQA22_RS25860 (140463) | 140463..140588 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| QQA22_RS25865 (140808) | 140808..141038 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| QQA22_RS25870 (141036) | 141036..141209 | - | 174 | Protein_142 | hypothetical protein | - |
| QQA22_RS25875 (141279) | 141279..141485 | + | 207 | WP_000547939.1 | hypothetical protein | - |
| QQA22_RS25880 (141510) | 141510..141797 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| QQA22_RS25885 (141918) | 141918..142739 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| QQA22_RS25890 (143036) | 143036..143638 | - | 603 | WP_000243709.1 | hypothetical protein | VF |
| QQA22_RS25895 (143959) | 143959..144342 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| QQA22_RS25900 (144529) | 144529..145218 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| QQA22_RS25905 (145311) | 145311..145712 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| QQA22_RS25910 (145745) | 145745..146110 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| QQA22_RS25915 (146125) | 146125..146436 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| QQA22_RS25920 (146458) | 146458..147024 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| QQA22_RS25925 (147011) | 147011..147739 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| QQA22_RS25930 (147739) | 147739..149166 | + | 1428 | WP_000146692.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| QQA22_RS25935 (149156) | 149156..149746 | + | 591 | WP_000002792.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| QQA22_RS25940 (149733) | 149733..149930 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| QQA22_RS25945 (149942) | 149942..150193 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| QQA22_RS25950 (150190) | 150190..150705 | + | 516 | WP_289245671.1 | type IV conjugative transfer system lipoprotein TraV | - |
| QQA22_RS25955 (150840) | 150840..151061 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| QQA22_RS25960 (151221) | 151221..153848 | + | 2628 | WP_039005851.1 | type IV secretion system protein TraC | - |
| QQA22_RS25965 (153845) | 153845..154231 | + | 387 | WP_000097319.1 | type-F conjugative transfer system protein TrbI | - |
| QQA22_RS25970 (154228) | 154228..154860 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| QQA22_RS25975 (154857) | 154857..155849 | + | 993 | WP_000830187.1 | conjugal transfer pilus assembly protein TraU | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|