Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/RelE-RHH |
| Location | 89230..89777 | Replicon | plasmid pEND_Eco 12049-1 |
| Accession | NZ_CP126953 | ||
| Organism | Escherichia coli O78:H4 strain APEC E12049 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | QQA22_RS25565 | Protein ID | WP_097309154.1 |
| Coordinates | 89230..89508 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | E1QMW3 |
| Locus tag | QQA22_RS25570 | Protein ID | WP_000079941.1 |
| Coordinates | 89508..89777 (-) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQA22_RS25535 (85494) | 85494..85628 | - | 135 | WP_249531455.1 | hypothetical protein | - |
| QQA22_RS25540 (85588) | 85588..86529 | - | 942 | WP_039005283.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| QQA22_RS25545 (86710) | 86710..87010 | + | 301 | Protein_77 | hypothetical protein | - |
| QQA22_RS25550 (87088) | 87088..87435 | - | 348 | WP_000142437.1 | DUF6404 family protein | - |
| QQA22_RS25555 (87737) | 87737..88219 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| QQA22_RS25560 (88336) | 88336..89184 | - | 849 | WP_001058005.1 | 3'-5' exonuclease | - |
| QQA22_RS25565 (89230) | 89230..89508 | - | 279 | WP_097309154.1 | type II toxin-antitoxin system toxin YacB | Toxin |
| QQA22_RS25570 (89508) | 89508..89777 | - | 270 | WP_000079941.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin |
| QQA22_RS25575 (90299) | 90299..91527 | + | 1229 | WP_289245670.1 | IS3 family transposase | - |
| QQA22_RS25580 (91724) | 91724..92998 | + | 1275 | WP_000489607.1 | HlyD family secretion protein | - |
| QQA22_RS25585 (93105) | 93105..93377 | + | 273 | Protein_85 | cysteine peptidase family C39 domain-containing protein | - |
| QQA22_RS25590 (93558) | 93558..94544 | + | 987 | Protein_86 | IS4-like element IS421 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | sitABCD | vat / iroB / iroC / iroD / iroE / iroN / iucA / iucB / iucC / iucD / iutA | 1..155857 | 155857 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|