MGE detailed information
MGE type: Conjugative plasmid MGE length: 128466 bp
Accession: NZ_CP116154 Location: 1..128466 Organism: Escherichia coli strain DETEC-P61 Replicon: plasmid pDETEC38
Accession: NZ_CP116154 Location: 1..128466 Organism: Escherichia coli strain DETEC-P61 Replicon: plasmid pDETEC38
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIC71_RS23545 (165) | 165..678 | - | 514 | Protein_0 | DUF4113 domain-containing protein | - |
| PIC71_RS23550 (739) | 739..843 | - | 105 | Protein_1 | AAA family ATPase | - |
| PIC71_RS23555 (845) | 845..1168 | - | 324 | Protein_2 | IS21 family transposase IS21 | Transposase |
| PIC71_RS23560 (1914) | 1914..2891 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| PIC71_RS23565 (3176) | 3176..3916 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| PIC71_RS23570 (4037) | 4037..4219 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| PIC71_RS23575 (4286) | 4286..4575 | - | 290 | Protein_6 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PIC71_RS23580 (4562) | 4562..4830 | - | 269 | Protein_7 | type II toxin-antitoxin system ParD family antitoxin | - |
| PIC71_RS23585 (4991) | 4991..6219 | + | 1229 | WP_113708090.1 | IS3 family transposase IS2 | Transposase |
| PIC71_RS23590 (6698) | 6698..7612 | + | 915 | WP_223429136.1 | hypothetical protein | - |
| PIC71_RS23595 (7901) | 7901..8029 | + | 129 | Protein_10 | IS481 family transposase | - |
| PIC71_RS23600 (8154) | 8154..8357 | - | 204 | Protein_11 | hypothetical protein | - |
| PIC71_RS23605 (8463) | 8463..8738 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| PIC71_RS23610 (8738) | 8738..9022 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| PIC71_RS23615 (9627) | 9627..10379 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| PIC71_RS23620 (10425) | 10425..10694 | - | 270 | Protein_15 | 2-keto-3-deoxygluconate permease | - |
| PIC71_RS23625 (10755) | 10755..11459 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC71_RS23630 (11512) | 11512..11748 | - | 237 | Protein_17 | DUF3330 domain-containing protein | - |
| PIC71_RS23635 (11951) | 11951..12964 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| PIC71_RS23640 (13113) | 13113..13951 | + | 839 | Protein_19 | Streptomycin 3''-adenylyltransferase | ARG |
| PIC71_RS23650 (15026) | 15026..15298 | - | 273 | Protein_21 | IS1 family transposase | - |
| PIC71_RS23655 (15392) | 15392..16825 | + | 1434 | WP_001288435.1 | DNA cytosine methyltransferase | - |
| PIC71_RS23660 (16859) | 16859..18073 | - | 1215 | WP_001532073.1 | type II site-specific deoxyribonuclease | - |
| PIC71_RS23665 (18368) | 18368..19072 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC71_RS23670 (19567) | 19567..20151 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| PIC71_RS23675 (20151) | 20151..21389 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| PIC71_RS23680 (21386) | 21386..22300 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| PIC71_RS23685 (22422) | 22422..23126 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC71_RS23690 (23191) | 23191..24351 | + | 1161 | Protein_29 | Tn3 family transposase TnpA_IS3000 | Transposase |
| PIC71_RS23695 (24628) | 24628..25572 | + | 945 | WP_100183899.1 | IS30 family transposase ISAba125 | Transposase |
| PIC71_RS23700 (25681) | 25681..26661 | - | 981 | WP_000019402.1 | IS5 family transposase IS5D | Transposase |
| PIC71_RS23705 (26896) | 26896..27708 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| PIC71_RS23710 (27712) | 27712..28077 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| PIC71_RS23715 (28082) | 28082..28720 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| PIC71_RS23720 (28731) | 28731..29288 | - | 558 | Protein_35 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| PIC71_RS23725 (29388) | 29388..29762 | - | 375 | Protein_36 | protein-disulfide reductase DsbD family protein | - |
| PIC71_RS23730 (29767) | 29767..29901 | - | 135 | WP_023408307.1 | divalent cation tolerance protein CutA | - |
| PIC71_RS23735 (29960) | 29960..30664 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC71_RS23740 (30730) | 30730..31275 | + | 546 | Protein_39 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PIC71_RS23745 (31311) | 31311..31726 | - | 416 | Protein_40 | IS1-like element IS1B family transposase | - |
| PIC71_RS23750 (31975) | 31975..32376 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| PIC71_RS23755 (32309) | 32309..32566 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| PIC71_RS23760 (32659) | 32659..33312 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| PIC71_RS23765 (34126) | 34126..35697 | - | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| PIC71_RS23770 (35717) | 35717..36064 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| PIC71_RS23775 (36064) | 36064..36741 | - | 678 | WP_001682408.1 | IS66 family transposase ISCro1 | Transposase |
| PIC71_RS23780 (36958) | 36958..37815 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| PIC71_RS23785 (37808) | 37808..37882 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| PIC71_RS23790 (38120) | 38120..38374 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| PIC71_RS23795 (38614) | 38614..39204 | - | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| PIC71_RS23800 (39242) | 39242..39451 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| PIC71_RS23805 (39497) | 39497..39958 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| PIC71_RS23810 (40203) | 40203..40415 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| PIC71_RS23815 (40544) | 40544..41104 | - | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| PIC71_RS23820 (41207) | 41207..42067 | - | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| PIC71_RS23825 (42126) | 42126..42872 | - | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| PIC71_RS23830 (42892) | 42892..48162 | - | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| PIC71_RS23835 (48162) | 48162..50360 | - | 2199 | WP_000009332.1 | type IV conjugative transfer system coupling protein TraD | - |
| PIC71_RS23840 (50411) | 50411..51148 | - | 738 | WP_000199905.1 | hypothetical protein | - |
| PIC71_RS23845 (51351) | 51351..52082 | - | 732 | WP_266068881.1 | conjugal transfer complement resistance protein TraT | - |
| PIC71_RS23850 (52131) | 52131..52616 | - | 486 | WP_000605870.1 | hypothetical protein | - |
| PIC71_RS23855 (52632) | 52632..55454 | - | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PIC71_RS23860 (55451) | 55451..56824 | - | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| PIC71_RS23865 (56811) | 56811..57203 | - | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| PIC71_RS23870 (57184) | 57184..57531 | - | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| PIC71_RS23875 (57461) | 57461..58006 | - | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PIC71_RS23880 (57993) | 57993..58277 | - | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PIC71_RS23885 (58396) | 58396..58740 | - | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| PIC71_RS23890 (58754) | 58754..59497 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PIC71_RS23895 (59490) | 59490..59747 | - | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| PIC71_RS23900 (59774) | 59774..61624 | - | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PIC71_RS23905 (61621) | 61621..62259 | - | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PIC71_RS23910 (62268) | 62268..62573 | - | 306 | WP_000224416.1 | hypothetical protein | - |
| PIC71_RS23915 (62603) | 62603..63595 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| PIC71_RS23920 (63592) | 63592..64224 | - | 633 | WP_001203728.1 | type-F conjugative transfer system protein TraW | - |
| PIC71_RS23925 (64221) | 64221..64607 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| PIC71_RS23930 (64604) | 64604..67234 | - | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| PIC71_RS23935 (67360) | 67360..67707 | - | 348 | WP_000836682.1 | hypothetical protein | - |
| PIC71_RS23940 (67735) | 67735..67953 | - | 219 | WP_000556745.1 | hypothetical protein | - |
| PIC71_RS23945 (68033) | 68033..68506 | - | 474 | WP_000549568.1 | hypothetical protein | - |
| PIC71_RS23950 (68499) | 68499..68912 | - | 414 | WP_000549589.1 | hypothetical protein | - |
| PIC71_RS23955 (68905) | 68905..69126 | - | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| PIC71_RS23960 (69261) | 69261..69776 | - | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PIC71_RS23965 (69773) | 69773..70093 | - | 321 | WP_001057307.1 | conjugal transfer protein TrbD | - |
| PIC71_RS23970 (70080) | 70080..70646 | - | 567 | WP_000896599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| PIC71_RS23975 (70636) | 70636..72087 | - | 1452 | WP_000146675.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PIC71_RS23980 (72087) | 72087..72815 | - | 729 | WP_001230772.1 | type-F conjugative transfer system secretin TraK | - |
| PIC71_RS23985 (72802) | 72802..73368 | - | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| PIC71_RS23990 (73390) | 73390..73701 | - | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| PIC71_RS23995 (73716) | 73716..74075 | - | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
| PIC71_RS24000 (74108) | 74108..74335 | - | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| PIC71_RS24005 (74472) | 74472..75143 | - | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| PIC71_RS24010 (75337) | 75337..75720 | - | 384 | WP_001354030.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PIC71_RS24015 (76043) | 76043..76645 | + | 603 | WP_000243713.1 | hypothetical protein | VF |
| PIC71_RS24020 (76942) | 76942..77763 | - | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| PIC71_RS24025 (77874) | 77874..78170 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| PIC71_RS24030 (78470) | 78470..78766 | + | 297 | Protein_97 | hypothetical protein | - |
| PIC71_RS24035 (79085) | 79085..79210 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PIC71_RS24040 (79152) | 79152..79301 | - | 150 | Protein_99 | plasmid maintenance protein Mok | - |
| PIC71_RS24045 (79323) | 79323..79502 | + | 180 | WP_001309233.1 | hypothetical protein | - |
| - (79287) | 79287..79511 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (79287) | 79287..79511 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (79287) | 79287..79511 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (79287) | 79287..79511 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| PIC71_RS24050 (79480) | 79480..80242 | - | 763 | Protein_101 | plasmid SOS inhibition protein A | - |
| PIC71_RS24055 (80239) | 80239..80673 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| PIC71_RS24060 (80742) | 80742..82765 | - | 2024 | Protein_103 | ParB/RepB/Spo0J family partition protein | - |
| PIC71_RS24065 (82826) | 82826..83059 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| PIC71_RS24070 (83117) | 83117..83644 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| PIC71_RS24075 (83946) | 83946..84401 | + | 456 | Protein_106 | hypothetical protein | - |
| PIC71_RS24080 (84487) | 84487..85050 | - | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| PIC71_RS24085 (85097) | 85097..86458 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| PIC71_RS24090 (86510) | 86510..86740 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| PIC71_RS24095 (87257) | 87257..87505 | + | 249 | WP_077249352.1 | hypothetical protein | - |
| PIC71_RS24100 (87778) | 87778..87969 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| PIC71_RS24105 (87966) | 87966..88388 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| PIC71_RS24110 (88435) | 88435..88860 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| PIC71_RS24115 (89277) | 89277..90053 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| PIC71_RS24120 (90104) | 90104..90622 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| PIC71_RS24125 (90552) | 90552..90773 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| PIC71_RS24130 (90774) | 90774..91457 | - | 684 | WP_000086185.1 | DNA methylase | - |
| PIC71_RS24135 (91534) | 91534..91845 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| PIC71_RS24140 (91842) | 91842..92744 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| PIC71_RS24145 (93611) | 93611..94582 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| PIC71_RS24150 (94582) | 94582..95748 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| PIC71_RS24155 (96336) | 96336..97091 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| PIC71_RS24160 (97865) | 97865..98671 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| PIC71_RS24165 (98672) | 98672..98977 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| PIC71_RS24170 (98979) | 98979..99197 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| PIC71_RS24175 (99765) | 99765..100277 | + | 513 | WP_000151784.1 | hypothetical protein | - |
| PIC71_RS24180 (100311) | 100311..101444 | - | 1134 | WP_001542067.1 | DUF3800 domain-containing protein | - |
| PIC71_RS24185 (101611) | 101611..102384 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| PIC71_RS24190 (102397) | 102397..102897 | - | 501 | WP_000528931.1 | HEPN family nuclease | - |
| PIC71_RS24195 (103162) | 103162..103392 | + | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PIC71_RS24200 (103389) | 103389..103805 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PIC71_RS24205 (103850) | 103850..107644 | - | 3795 | WP_001144732.1 | hypothetical protein | - |
| PIC71_RS24210 (108025) | 108025..108255 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PIC71_RS24215 (108252) | 108252..108668 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PIC71_RS24220 (108743) | 108743..110308 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| PIC71_RS24225 (110293) | 110293..111315 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| PIC71_RS24235 (112646) | 112646..114847 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| PIC71_RS24240 (114873) | 114873..116206 | - | 1334 | Protein_139 | L-lysine N6-monooxygenase | VF |
| PIC71_RS24245 (116203) | 116203..117945 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| PIC71_RS24250 (117945) | 117945..118892 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| PIC71_RS24255 (118893) | 118893..120617 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| PIC71_RS24260 (120753) | 120753..121946 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| PIC71_RS24265 (122326) | 122326..122706 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| PIC71_RS24270 (123047) | 123047..123460 | - | 414 | Protein_145 | phosphopyruvate hydratase | - |
| PIC71_RS24275 (123458) | 123458..123715 | + | 258 | Protein_146 | Tn3 family transposase | - |
| PIC71_RS24280 (123949) | 123949..124806 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| PIC71_RS24285 (124803) | 124803..125660 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| PIC71_RS24290 (125657) | 125657..126484 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| PIC71_RS24295 (126484) | 126484..127398 | - | 915 | WP_072644633.1 | putative periplasmic iron-binding protein | VF |
| PIC71_RS24300 (127754) | 127754..128451 | + | 698 | WP_223155668.1 | IS1 family transposase IS1A | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|