NZ_CP1109981..168068

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 168068 bp
Accession: NZ_CP110998        Location: 1..168068         Organism: Escherichia coli strain XYEH3783       Replicon: plasmid pYUXYEH3783-NDM


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ORI30_RS24500 () 237..491 + 255 WP_000083830.1 replication regulatory protein RepA -
ORI30_RS24505 () 729..803 + 75 WP_001365705.1 RepA leader peptide Tap -
ORI30_RS24510 () 796..1653 + 858 WP_000130646.1 incFII family plasmid replication initiator RepA -
ORI30_RS24515 () 1870..2547 + 678 WP_001682408.1 IS66 family transposase ISCro1 Transposase
ORI30_RS24520 () 2547..2894 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
ORI30_RS24525 () 2914..4485 + 1572 WP_000381395.1 IS66 family transposase ISCro1 Transposase
ORI30_RS24530 () 5299..5952 + 654 WP_000616800.1 type II CAAX endopeptidase family protein -
ORI30_RS24535 () 6045..6302 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
ORI30_RS24540 () 6235..6636 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
ORI30_RS24545 () 6921..8693 + 1773 WP_001262766.1 DUF262 domain-containing protein -
ORI30_RS24550 () 9386..9820 - 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
ORI30_RS24555 () 9892..10242 + 351 WP_001294663.1 mercuric transport protein MerT -
ORI30_RS24560 () 10256..10531 + 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
ORI30_RS24565 () 10567..10989 + 423 WP_001340589.1 organomercurial transporter MerC -
ORI30_RS24570 () 11041..12735 + 1695 WP_000105636.1 mercury(II) reductase -
ORI30_RS24575 () 12753..13115 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
ORI30_RS24580 () 13112..13348 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
ORI30_RS24585 () 13384..14052 + 669 WP_001300294.1 putative signaling protein VF
ORI30_RS24590 () 14172..14876 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
ORI30_RS24595 () 14882..15022 + 141 WP_001044210.1 hypothetical protein -
ORI30_RS24600 () 15508..16245 + 738 WP_001366550.1 Tn3 family transposase TnpR_TnEc1 Transposase
ORI30_RS24605 () 16242..16466 + 225 WP_000743213.1 hypothetical protein -
ORI30_RS24610 () 16677..18170 + 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
ORI30_RS24615 () 18201..19085 + 885 WP_021598067.1 DUF3363 domain-containing protein -
ORI30_RS24620 () 19302..20516 + 1215 WP_023300759.1 Bicyclomycin resistance protein ARG
ORI30_RS24625 () 20544..20849 + 306 WP_001255015.1 HTH-type transcriptional regulator HdfR VF
ORI30_RS24630 () 20961..21149 + 189 Protein_26 IS91 family transposase -
ORI30_RS24635 () 21116..22315 - 1200 WP_032153701.1 Tetracycline resistance protein, class C ARG
ORI30_RS24640 () 22421..23071 + 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
ORI30_RS24645 () 23103..23345 - 243 WP_000844627.1 transposase -
ORI30_RS24650 () 23403..26369 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
ORI30_RS24655 () 26373..26933 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
ORI30_RS24660 () 27109..27459 - 351 WP_071830595.1 DUF3330 domain-containing protein -
ORI30_RS24665 () 27662..28675 - 1014 WP_000845039.1 IS91 family transposase ISAzo26 Transposase
ORI30_RS24670 () 28820..29317 + 498 WP_001083725.1 IS1595 family transposase ISSsu9 ARG
ORI30_RS24675 () 29429..29719 + 291 WP_001336345.1 DUF1010 domain-containing protein -
ORI30_RS24680 () 29725..30563 + 839 Protein_36 Streptomycin 3''-adenylyltransferase ARG
ORI30_RS24685 () 30778..32037 + 1260 WP_000095725.1 chloramphenicol efflux MFS transporter CmlA1 ARG
ORI30_RS24690 () 32130..32968 + 839 Protein_38 Streptomycin 3''-adenylyltransferase ARG
ORI30_RS24695 () 33091..33237 + 147 Protein_39 SMR family transporter -
ORI30_RS24700 () 33271..33936 - 666 Protein_40 Tn3 family transposase TnpA_Tn3 Transposase
ORI30_RS24705 () 33990..34694 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
ORI30_RS24710 () 34731..35858 - 1128 WP_014837927.1 DUF3883 domain-containing protein -
ORI30_RS24715 () 35909..36136 - 228 WP_000248278.1 hypothetical protein -
ORI30_RS24720 () 36160..36351 + 192 WP_000951934.1 hypothetical protein -
ORI30_RS24725 () 36833..37375 - 543 WP_000587837.1 AAA family ATPase -
ORI30_RS24730 () 37388..38248 - 861 WP_000557454.1 SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
ORI30_RS24735 () 38391..38906 + 516 Protein_47 IS4 family transposase IS10R Transposase
ORI30_RS24740 () 38959..39663 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
ORI30_RS24745 () 39729..40043 + 315 Protein_49 recombinase family protein -
ORI30_RS24750 () 40362..41018 - 657 WP_001516695.1 Pentapeptide repeat protein ARG
ORI30_RS24755 () 41413..42428 + 1016 Protein_51 IS3 family transposase ISEc36 Transposase
ORI30_RS24760 () 42471..45476 - 3006 WP_001143760.1 Tn3 family transposase TnpA_Tn3 Transposase
ORI30_RS24765 () 45640..46197 + 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
ORI30_RS24770 () 46380..47240 + 861 WP_000027057.1 Beta-lactamase TEM ARG
ORI30_RS24775 () 47390..47578 + 189 Protein_55 SMR family transporter -
ORI30_RS24780 () 47825..48457 - 633 WP_020802982.1 IS256 family transposase IS406 Transposase
ORI30_RS24785 () 48480..48755 + 276 WP_109023896.1 hypothetical protein -
ORI30_RS24790 () 48758..49549 - 792 WP_000034420.1 Dihydropteroate synthase ARG
ORI30_RS24795 () 50018..50263 - 246 WP_001354008.1 GrpB family protein -
ORI30_RS24800 () 50301..51164 - 864 WP_000612791.1 SDR family oxidoreductase -
ORI30_RS24805 () 51310..51567 - 258 Protein_61 hypothetical protein -
ORI30_RS24810 () 51622..52326 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
ORI30_RS24815 () 52385..52519 + 135 WP_023408307.1 divalent cation tolerance protein CutA -
ORI30_RS24820 () 52524..52898 + 375 Protein_64 protein-disulfide reductase DsbD family protein -
ORI30_RS24825 () 52998..53555 + 558 Protein_65 twin-arginine translocation (TAT) pathway signal sequence domain protein -
ORI30_RS24830 () 53566..54204 - 639 WP_004201168.1 phosphoribosylanthranilate isomerase -
ORI30_RS24835 () 54209..54574 - 366 WP_004201167.1 bleomycin binding protein Ble-MBL -
ORI30_RS24840 () 54578..55390 - 813 WP_023408309.1 Metallo-beta-lactamase type 2 ARG
ORI30_RS24845 () 55625..56605 + 981 WP_000019402.1 IS5 family transposase IS5D Transposase
ORI30_RS24850 () 56714..57658 - 945 WP_100183899.1 IS30 family transposase ISAba125 Transposase
ORI30_RS24855 () 57935..59095 - 1161 Protein_71 Tn3 family transposase TnpA_IS3000 Transposase
ORI30_RS24860 () 59160..59864 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
ORI30_RS24865 () 60159..61373 + 1215 WP_001532073.1 type II site-specific deoxyribonuclease -
ORI30_RS24870 () 61407..62840 - 1434 WP_001288435.1 DNA cytosine methyltransferase -
ORI30_RS24875 () 62934..63206 + 273 Protein_75 IS1 family transposase -
ORI30_RS24880 () 63463..64160 + 698 WP_095033700.1 IS1 family transposase IS1R Transposase
ORI30_RS24885 () 64281..65119 - 839 Protein_77 Streptomycin 3''-adenylyltransferase ARG
ORI30_RS24890 () 65268..66281 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
ORI30_RS24895 () 66484..66720 + 237 Protein_79 DUF3330 domain-containing protein -
ORI30_RS24900 () 66773..67477 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
ORI30_RS24905 () 67538..67807 + 270 Protein_81 2-keto-3-deoxygluconate permease -
ORI30_RS24910 () 67853..68605 - 753 WP_000562172.1 IclR family transcriptional regulator -
ORI30_RS24915 () 69210..69494 + 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
ORI30_RS24920 () 69494..69769 + 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
ORI30_RS24925 () 69875..70078 + 204 Protein_85 hypothetical protein -
ORI30_RS24930 () 70203..70331 - 129 Protein_86 IS481 family transposase -
ORI30_RS24935 () 70620..71534 - 915 WP_223429136.1 hypothetical protein -
ORI30_RS24945 () 73402..73670 + 269 Protein_89 type II toxin-antitoxin system ParD family antitoxin -
ORI30_RS24950 () 73657..73946 + 290 Protein_90 type II toxin-antitoxin system RelE/ParE family toxin -
ORI30_RS24955 () 74013..74195 + 183 WP_042344623.1 hypothetical protein -
ORI30_RS24960 () 74316..75056 + 741 WP_001066953.1 tyrosine-type recombinase/integrase -
ORI30_RS24965 () 75341..76318 - 978 WP_266068911.1 RepB family plasmid replication initiator protein -
ORI30_RS24970 () 77064..77387 + 324 Protein_94 IS21 family transposase IS21 Transposase
ORI30_RS24975 () 77389..77493 + 105 Protein_95 AAA family ATPase -
ORI30_RS24980 () 77554..78067 + 514 Protein_96 DUF4113 domain-containing protein -
ORI30_RS24990 () 79300..80214 + 915 WP_072644633.1 putative periplasmic iron-binding protein VF
ORI30_RS24995 () 80214..81041 + 828 WP_000983710.1 Manganese transport system ATP-binding protein MntB VF
ORI30_RS25000 () 81038..81895 + 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
ORI30_RS25005 () 81892..82749 + 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
ORI30_RS25010 () 83238..83651 + 414 Protein_102 phosphopyruvate hydratase -
ORI30_RS25015 () 83992..84372 + 381 WP_001318207.1 fluoride efflux transporter CrcB -
ORI30_RS25020 () 84752..85937 - 1186 Protein_104 MFS transporter -
ORI30_RS25025 () 86073..87797 + 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
ORI30_RS25030 () 87798..88745 + 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
ORI30_RS25035 () 88745..90486 + 1742 Protein_107 Aerobactin synthase VF
ORI30_RS25040 () 90483..91816 + 1334 Protein_108 L-lysine N6-monooxygenase VF
ORI30_RS25045 () 91842..94043 + 2202 WP_000973519.1 Ferric aerobactin receptor VF
ORI30_RS25050 () 94423..95120 + 698 WP_223155668.1 IS1 family transposase IS1A Transposase
ORI30_RS25055 () 95374..96396 - 1023 WP_000361402.1 helicase UvrD -
ORI30_RS25060 () 96381..97946 - 1566 WP_001128474.1 AAA family ATPase -
ORI30_RS25065 () 98021..98437 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
ORI30_RS25070 () 98434..98664 - 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
ORI30_RS25075 () 99045..102839 + 3795 WP_001144732.1 hypothetical protein -
ORI30_RS25080 () 102884..103300 - 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
ORI30_RS25085 () 103297..103527 - 231 WP_001261278.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
ORI30_RS25090 () 103792..104292 + 501 WP_000528931.1 HEPN family nuclease -
ORI30_RS25095 () 104305..105078 + 774 WP_000905949.1 hypothetical protein -
ORI30_RS25100 () 105245..106378 + 1134 WP_001542067.1 DUF3800 domain-containing protein -
ORI30_RS25105 () 106412..106900 - 489 WP_011254646.1 hypothetical protein -
ORI30_RS25110 () 107492..107710 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
ORI30_RS25115 () 107712..108017 + 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
ORI30_RS25120 () 108018..108824 + 807 WP_000016982.1 site-specific integrase -
ORI30_RS25125 () 109598..110353 + 756 WP_000852146.1 replication initiation protein RepE -
ORI30_RS25130 () 110941..112107 + 1167 WP_000772446.1 hypothetical protein VF
ORI30_RS25135 () 112107..113078 + 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
ORI30_RS25140 () 113945..114847 + 903 WP_001348615.1 DUF1281 domain-containing protein -
ORI30_RS25145 () 114844..115155 + 312 WP_011254640.1 hypothetical protein -
ORI30_RS25150 () 115232..115915 + 684 WP_000086185.1 DNA methylase -
ORI30_RS25155 () 115916..116137 + 222 WP_001104873.1 hypothetical protein -
ORI30_RS25160 () 116067..116585 + 519 WP_123325260.1 DUF1380 family protein -
ORI30_RS25165 () 116636..117412 + 777 WP_001753849.1 hypothetical protein -
ORI30_RS25170 () 117829..118254 + 426 WP_001198928.1 antirestriction protein -
ORI30_RS25175 () 118301..118723 + 423 WP_000271753.1 DUF1380 family protein -
ORI30_RS25180 () 118720..118911 + 192 WP_001027516.1 hypothetical protein -
ORI30_RS25185 () 119184..119432 - 249 WP_077249352.1 hypothetical protein -
ORI30_RS25190 () 119949..120179 + 231 WP_000218642.1 hypothetical protein -
ORI30_RS25195 () 120231..121592 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
ORI30_RS25200 () 121639..122202 + 564 WP_001298559.1 class I SAM-dependent methyltransferase -
ORI30_RS25205 () 122288..122743 - 456 Protein_141 hypothetical protein -
ORI30_RS25210 () 123045..123572 + 528 WP_000290834.1 single-stranded DNA-binding protein -
ORI30_RS25215 () 123630..123863 + 234 WP_000006003.1 DUF905 family protein -
ORI30_RS25220 () 123924..125947 + 2024 Protein_144 ParB/RepB/Spo0J family partition protein -
ORI30_RS25225 () 126016..126450 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
ORI30_RS25230 () 126447..127209 + 763 Protein_146 plasmid SOS inhibition protein A -
- () 127178..127402 + 225 NuclAT_0 - -
- () 127178..127402 + 225 NuclAT_0 - -
- () 127178..127402 + 225 NuclAT_0 - -
- () 127178..127402 + 225 NuclAT_0 - -
ORI30_RS25235 () 127187..127366 - 180 WP_001309233.1 hypothetical protein -
- 127335..127400 - 66 - - Antitoxin Detail
ORI30_RS25240 () 127388..127537 + 150 Protein_148 plasmid maintenance protein Mok -
ORI30_RS25245 () 127479..127604 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
ORI30_RS25250 () 127923..128219 - 297 Protein_150 hypothetical protein -
ORI30_RS25255 () 128519..128815 + 297 WP_001272251.1 hypothetical protein -
ORI30_RS25260 () 128926..129747 + 822 WP_001234445.1 DUF932 domain-containing protein -
ORI30_RS25265 () 130044..130634 - 591 WP_000252683.1 hypothetical protein VF
ORI30_RS25270 () 130969..131352 + 384 WP_001354030.1 conjugal transfer relaxosome DNA-binding protein TraM -
ORI30_RS25275 () 131546..132217 + 672 WP_000283561.1 conjugal transfer transcriptional regulator TraJ -
ORI30_RS25280 () 132354..132581 + 228 WP_000089263.1 conjugal transfer relaxosome protein TraY -
ORI30_RS25285 () 132614..132973 + 360 WP_001098992.1 type IV conjugative transfer system pilin TraA -
ORI30_RS25290 () 132988..133299 + 312 WP_000012113.1 type IV conjugative transfer system protein TraL -
ORI30_RS25295 () 133321..133887 + 567 WP_000399780.1 type IV conjugative transfer system protein TraE -
ORI30_RS25300 () 133874..134602 + 729 WP_001230772.1 type-F conjugative transfer system secretin TraK -
ORI30_RS25305 () 134602..136053 + 1452 WP_000146675.1 F-type conjugal transfer pilus assembly protein TraB -
ORI30_RS25310 () 136043..136609 + 567 WP_000896599.1 conjugal transfer pilus-stabilizing protein TraP -
ORI30_RS25315 () 136596..136916 + 321 WP_001057307.1 conjugal transfer protein TrbD -
ORI30_RS25320 () 136913..137428 + 516 WP_000809881.1 type IV conjugative transfer system lipoprotein TraV -
ORI30_RS25325 () 137563..137784 + 222 WP_001278683.1 conjugal transfer protein TraR -
ORI30_RS25330 () 137777..138190 + 414 WP_000549589.1 hypothetical protein -
ORI30_RS25335 () 138183..138656 + 474 WP_000549568.1 hypothetical protein -
ORI30_RS25340 () 138736..138954 + 219 WP_000556745.1 hypothetical protein -
ORI30_RS25345 () 138982..139329 + 348 WP_000836682.1 hypothetical protein -
ORI30_RS25350 () 139455..142085 + 2631 WP_000069777.1 type IV secretion system protein TraC -
ORI30_RS25355 () 142082..142468 + 387 WP_000214084.1 type-F conjugative transfer system protein TrbI -
ORI30_RS25360 () 142465..143097 + 633 WP_001203728.1 type-F conjugative transfer system protein TraW -
ORI30_RS25365 () 143094..144086 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
ORI30_RS25370 () 144116..144421 + 306 WP_000224416.1 hypothetical protein -
ORI30_RS25375 () 144430..145068 + 639 WP_001080256.1 type-F conjugative transfer system pilin assembly protein TrbC -
ORI30_RS25380 () 145065..146915 + 1851 WP_000821856.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
ORI30_RS25385 () 146942..147199 + 258 WP_000864353.1 conjugal transfer protein TrbE -
ORI30_RS25390 () 147192..147935 + 744 WP_001030371.1 type-F conjugative transfer system pilin assembly protein TraF -
ORI30_RS25395 () 147949..148272 + 324 WP_266068871.1 conjugal transfer protein TrbA -
ORI30_RS25400 () 148411..148695 + 285 WP_000624194.1 type-F conjugative transfer system pilin chaperone TraQ -
ORI30_RS25405 () 148682..149227 + 546 WP_000059831.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
ORI30_RS25410 () 149157..149504 + 348 WP_001309242.1 P-type conjugative transfer protein TrbJ -
ORI30_RS25415 () 149485..149877 + 393 WP_000660699.1 F-type conjugal transfer protein TrbF -
ORI30_RS25420 () 149864..151237 + 1374 WP_000944331.1 conjugal transfer pilus assembly protein TraH -
ORI30_RS25425 () 151234..154056 + 2823 WP_001007039.1 conjugal transfer mating-pair stabilization protein TraG -
ORI30_RS25430 () 154072..154557 + 486 WP_000605870.1 hypothetical protein -
ORI30_RS25435 () 154606..155337 + 732 WP_266068881.1 conjugal transfer complement resistance protein TraT -
ORI30_RS25440 () 155540..156277 + 738 WP_000199905.1 hypothetical protein -
ORI30_RS25445 () 156328..158517 + 2190 WP_017901267.1 type IV conjugative transfer system coupling protein TraD -
ORI30_RS25450 () 158517..163787 + 5271 WP_000948354.1 Multifunctional conjugation protein TraI Relaxase
ORI30_RS25455 () 163807..164553 + 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
ORI30_RS25460 () 164612..165472 + 861 WP_000704523.1 Quorum-quenching protein AidA VF
ORI30_RS25465 () 165575..166135 + 561 WP_000139323.1 fertility inhibition protein FinO -
ORI30_RS25470 () 166264..166476 + 213 WP_001309245.1 ANR family transcriptional regulator -
ORI30_RS25475 () 166721..167182 + 462 WP_001233838.1 thermonuclease family protein -
ORI30_RS25480 () 167228..167437 + 210 WP_001298565.1 hemolysin expression modulator Hha -
ORI30_RS25485 () 167475..168065 + 591 WP_000766807.1 DUF2726 domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance