MGE detailed information
MGE type: Conjugative plasmid MGE length: 133748 bp
Accession: NZ_CP109875 Location: 1..133748 Organism: Escherichia coli strain EC488 Replicon: plasmid pEC488-1
Accession: NZ_CP109875 Location: 1..133748 Organism: Escherichia coli strain EC488 Replicon: plasmid pEC488-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NQ150_RS25010 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| NQ150_RS25015 (1263) | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| NQ150_RS25020 (2124) | 2124..2306 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| NQ150_RS25025 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NQ150_RS25030 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| NQ150_RS25035 (3449) | 3449..3814 | + | 366 | Protein_5 | hypothetical protein | - |
| NQ150_RS25040 (3906) | 3906..5134 | + | 1229 | WP_088895425.1 | IS3 family transposase IS2 | Transposase |
| NQ150_RS25045 (5109) | 5109..5954 | + | 846 | WP_261630092.1 | hypothetical protein | - |
| NQ150_RS25050 (5987) | 5987..6115 | + | 129 | Protein_8 | IS481 family transposase | - |
| NQ150_RS25055 (6240) | 6240..6443 | - | 204 | Protein_9 | hypothetical protein | - |
| NQ150_RS25060 (6549) | 6549..6824 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NQ150_RS25065 (6824) | 6824..7108 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| NQ150_RS25070 (7713) | 7713..8465 | + | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| NQ150_RS25075 (8511) | 8511..9476 | - | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| NQ150_RS25080 (9509) | 9509..9889 | - | 381 | WP_024946717.1 | Rid family detoxifying hydrolase | - |
| NQ150_RS25085 (9914) | 9914..10804 | - | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| NQ150_RS25090 (11037) | 11037..11231 | - | 195 | WP_000796505.1 | hypothetical protein | - |
| NQ150_RS25095 (11205) | 11205..11645 | + | 441 | Protein_17 | zinc-binding dehydrogenase | - |
| NQ150_RS25100 (11776) | 11776..12654 | + | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| NQ150_RS25105 (12644) | 12644..13531 | + | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| NQ150_RS25110 (13542) | 13542..14366 | + | 825 | WP_000922702.1 | phosphodiesterase | - |
| NQ150_RS25115 (14372) | 14372..15445 | + | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| NQ150_RS25120 (15438) | 15438..16748 | + | 1311 | WP_099452347.1 | ABC transporter substrate-binding protein | - |
| NQ150_RS25125 (16807) | 16807..17115 | - | 309 | Protein_23 | IS4 family transposase ISEc13 | Transposase |
| NQ150_RS25130 (17192) | 17192..17365 | - | 174 | WP_000338295.1 | Tn3 family transposase ISPsy39 | Transposase |
| NQ150_RS25135 (17447) | 17447..18643 | - | 1197 | Protein_25 | IS3 family transposase | - |
| NQ150_RS25140 (18668) | 18668..19372 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NQ150_RS25145 (19432) | 19432..23013 | + | 3582 | Protein_27 | Multifunctional conjugation protein TraI | Relaxase |
| NQ150_RS25150 (23033) | 23033..23779 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| NQ150_RS25155 (23834) | 23834..24394 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| NQ150_RS25160 (24525) | 24525..24737 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| NQ150_RS25165 (25250) | 25250..25536 | + | 287 | Protein_31 | DUF2726 domain-containing protein | - |
| - (25503) | 25503..25563 | - | 61 | NuclAT_2 | - | - |
| - (25503) | 25503..25563 | - | 61 | NuclAT_2 | - | - |
| - (25503) | 25503..25563 | - | 61 | NuclAT_2 | - | - |
| - (25503) | 25503..25563 | - | 61 | NuclAT_2 | - | - |
| NQ150_RS25170 (25608) | 25608..25742 | + | 135 | WP_023144756.1 | Hok/Gef family protein | - |
| NQ150_RS25175 (26039) | 26039..26149 | + | 111 | Protein_33 | replication protein | - |
| NQ150_RS25180 (26218) | 26218..27000 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| NQ150_RS25185 (26997) | 26997..28019 | - | 1023 | WP_000255944.1 | IS21 family transposase IS100kyp | Transposase |
| NQ150_RS25190 (28106) | 28106..28252 | + | 147 | Protein_36 | replication protein A | - |
| NQ150_RS25195 (28358) | 28358..28489 | + | 132 | Protein_37 | protein CopA/IncA | - |
| NQ150_RS25200 (28489) | 28489..28563 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| NQ150_RS25205 (28556) | 28556..29413 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| NQ150_RS25210 (30353) | 30353..31006 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NQ150_RS25215 (31099) | 31099..31356 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NQ150_RS25220 (31289) | 31289..31690 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NQ150_RS25225 (31939) | 31939..32354 | + | 416 | Protein_43 | IS1-like element IS1B family transposase | - |
| NQ150_RS25230 (32390) | 32390..32935 | - | 546 | Protein_44 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NQ150_RS25235 (33001) | 33001..33705 | - | 705 | WP_264403717.1 | IS6 family transposase IS26 | Transposase |
| NQ150_RS25240 (33770) | 33770..34450 | - | 681 | Protein_46 | IS91 family transposase ISAzo26 | Transposase |
| NQ150_RS25245 (34608) | 34608..35081 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| NQ150_RS25250 (35212) | 35212..36000 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| NQ150_RS25255 (36206) | 36206..36553 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| NQ150_RS25260 (36547) | 36547..37386 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| NQ150_RS25265 (37514) | 37514..37717 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| NQ150_RS25270 (37873) | 37873..39078 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| NQ150_RS25275 (39089) | 39089..39394 | + | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| NQ150_RS25280 (39438) | 39438..39503 | + | 66 | Protein_54 | EAL domain-containing protein | - |
| NQ150_RS25285 (39621) | 39621..40385 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| NQ150_RS25290 (40878) | 40878..41462 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| NQ150_RS25295 (41462) | 41462..42700 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| NQ150_RS25300 (42697) | 42697..43602 | - | 906 | WP_001404365.1 | hypothetical protein | ARG |
| NQ150_RS25305 (43724) | 43724..44428 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NQ150_RS25310 (44563) | 44563..44658 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| NQ150_RS25315 (44784) | 44784..44882 | + | 99 | Protein_61 | rRNA adenine N-6-methyltransferase family protein | - |
| NQ150_RS25320 (44938) | 44938..45635 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| NQ150_RS25325 (45632) | 45632..45895 | + | 264 | WP_049802299.1 | antibiotic biosynthesis monooxygenase | - |
| NQ150_RS25330 (45888) | 45888..46274 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| NQ150_RS25335 (46282) | 46282..46968 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| NQ150_RS25340 (46946) | 46946..47569 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| NQ150_RS25345 (47651) | 47651..48856 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| NQ150_RS25350 (48969) | 48969..49562 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| NQ150_RS25360 (50618) | 50618..50731 | + | 114 | Protein_70 | IS6 family transposase IS15DI | Transposase |
| NQ150_RS25365 (50869) | 50869..51039 | + | 171 | Protein_71 | DsbA family protein | - |
| NQ150_RS25370 (51029) | 51029..51535 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| NQ150_RS25375 (51772) | 51772..52533 | + | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| NQ150_RS25380 (52880) | 52880..54766 | + | 1887 | WP_000118029.1 | FTR1 family protein | - |
| NQ150_RS25385 (54807) | 54807..55334 | + | 528 | WP_000178050.1 | iron transporter | - |
| NQ150_RS25390 (55438) | 55438..56817 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| NQ150_RS25395 (56820) | 56820..58103 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| NQ150_RS25400 (58093) | 58093..59223 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| NQ150_RS25405 (59228) | 59228..59923 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| NQ150_RS25410 (59910) | 59910..60395 | + | 486 | WP_001267177.1 | TlpA disulfide reductase family protein | - |
| NQ150_RS25415 (60420) | 60420..60905 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| NQ150_RS25420 (61027) | 61027..61557 | + | 531 | Protein_82 | histidine-type phosphatase | - |
| NQ150_RS25425 (61615) | 61615..62319 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NQ150_RS25430 (62387) | 62387..64072 | - | 1686 | Protein_84 | Multifunctional conjugation protein TraI | Relaxase |
| NQ150_RS25435 (64072) | 64072..66279 | - | 2208 | WP_021547900.1 | type IV conjugative transfer system coupling protein TraD | - |
| NQ150_RS25440 (66276) | 66276..67055 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| NQ150_RS25445 (67258) | 67258..67989 | - | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| NQ150_RS25450 (68021) | 68021..68518 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| NQ150_RS25455 (68537) | 68537..71356 | - | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NQ150_RS25460 (71353) | 71353..72726 | - | 1374 | WP_099452336.1 | conjugal transfer pilus assembly protein TraH | - |
| NQ150_RS25465 (72713) | 72713..73105 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| NQ150_RS25470 (73086) | 73086..73433 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| NQ150_RS25475 (73363) | 73363..73908 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NQ150_RS25480 (73895) | 73895..74179 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NQ150_RS25485 (74306) | 74306..74626 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| NQ150_RS25495 (75486) | 75486..76088 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| NQ150_RS25500 (76385) | 76385..77206 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| NQ150_RS25505 (77325) | 77325..77612 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| NQ150_RS25510 (77637) | 77637..77843 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| NQ150_RS25515 (77913) | 77913..78086 | + | 174 | Protein_101 | hypothetical protein | - |
| NQ150_RS25520 (78084) | 78084..78314 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| NQ150_RS25525 (78534) | 78534..78659 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NQ150_RS25530 (78601) | 78601..78750 | - | 150 | Protein_104 | plasmid maintenance protein Mok | - |
| - (78736) | 78736..78828 | - | 93 | NuclAT_1 | - | Antitoxin Detail |
| - (78736) | 78736..78828 | - | 93 | NuclAT_1 | - | Antitoxin Detail |
| - (78736) | 78736..78828 | - | 93 | NuclAT_1 | - | Antitoxin Detail |
| - (78736) | 78736..78828 | - | 93 | NuclAT_1 | - | Antitoxin Detail |
| - (80270) | 80270..80372 | - | 103 | NuclAT_0 | - | - |
| - (80270) | 80270..80372 | - | 103 | NuclAT_0 | - | - |
| - (80270) | 80270..80372 | - | 103 | NuclAT_0 | - | - |
| - (80270) | 80270..80372 | - | 103 | NuclAT_0 | - | - |
| NQ150_RS25540 (80341) | 80341..81103 | - | 763 | Protein_106 | plasmid SOS inhibition protein A | - |
| NQ150_RS25545 (81100) | 81100..81534 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| NQ150_RS25550 (81589) | 81589..83547 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| NQ150_RS25555 (83613) | 83613..83846 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| NQ150_RS25560 (83909) | 83909..84448 | - | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| NQ150_RS25565 (84474) | 84474..84680 | - | 207 | WP_000547975.1 | hypothetical protein | - |
| NQ150_RS25570 (84593) | 84593..84928 | - | 336 | WP_013023883.1 | hypothetical protein | - |
| NQ150_RS25575 (84921) | 84921..85166 | - | 246 | WP_071533131.1 | hypothetical protein | - |
| NQ150_RS25580 (85091) | 85091..85291 | - | 201 | WP_025492130.1 | hypothetical protein | - |
| NQ150_RS25585 (85317) | 85317..85880 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| NQ150_RS25590 (85928) | 85928..87289 | - | 1362 | WP_014106968.1 | DUF3560 domain-containing protein | - |
| NQ150_RS25595 (87341) | 87341..87571 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| NQ150_RS25600 (88088) | 88088..88336 | + | 249 | WP_071526484.1 | hypothetical protein | - |
| NQ150_RS25605 (88609) | 88609..88800 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| NQ150_RS25610 (88797) | 88797..89219 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| NQ150_RS25615 (89266) | 89266..89691 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| NQ150_RS25620 (90108) | 90108..90884 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| NQ150_RS25625 (90935) | 90935..91453 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| NQ150_RS25630 (91383) | 91383..91604 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| NQ150_RS25635 (91605) | 91605..92288 | - | 684 | WP_000086185.1 | DNA methylase | - |
| NQ150_RS25640 (92364) | 92364..92675 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| NQ150_RS25645 (92672) | 92672..93574 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| NQ150_RS25650 (94441) | 94441..95412 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NQ150_RS25655 (95412) | 95412..96578 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| NQ150_RS25660 (97166) | 97166..97921 | - | 756 | WP_024946706.1 | replication initiation protein RepE | - |
| NQ150_RS25665 (98695) | 98695..99501 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| NQ150_RS25670 (99502) | 99502..99807 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| NQ150_RS25675 (99809) | 99809..100027 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| NQ150_RS25680 (100618) | 100618..101106 | + | 489 | WP_011254646.1 | hypothetical protein | - |
| NQ150_RS25685 (101140) | 101140..102273 | - | 1134 | WP_001542067.1 | DUF3800 domain-containing protein | - |
| NQ150_RS25690 (102440) | 102440..103213 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| NQ150_RS25695 (103226) | 103226..103726 | - | 501 | WP_000528931.1 | HEPN family nuclease | - |
| NQ150_RS25700 (103991) | 103991..104221 | + | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NQ150_RS25705 (104218) | 104218..104634 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NQ150_RS25710 (104741) | 104741..106354 | - | 1614 | WP_000080193.1 | IS66 family transposase ISEc23 | Transposase |
| NQ150_RS25715 (106385) | 106385..106735 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| NQ150_RS25720 (106732) | 106732..107157 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| NQ150_RS25725 (107228) | 107228..111013 | - | 3786 | WP_261630093.1 | pcar | - |
| NQ150_RS25730 (111394) | 111394..111624 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NQ150_RS25735 (111621) | 111621..112037 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NQ150_RS25740 (112112) | 112112..113677 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| NQ150_RS25745 (113662) | 113662..114684 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| NQ150_RS25755 (115991) | 115991..116905 | + | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| NQ150_RS25760 (116905) | 116905..117732 | + | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| NQ150_RS25765 (117729) | 117729..118586 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| NQ150_RS25770 (118583) | 118583..119440 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| NQ150_RS25775 (119674) | 119674..119931 | - | 258 | Protein_153 | transposase | - |
| NQ150_RS25780 (119929) | 119929..120342 | + | 414 | Protein_154 | phosphopyruvate hydratase | - |
| NQ150_RS25785 (120683) | 120683..121063 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| NQ150_RS25790 (121443) | 121443..122636 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| NQ150_RS25795 (122772) | 122772..124496 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| NQ150_RS25800 (124497) | 124497..125444 | + | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| NQ150_RS25805 (125444) | 125444..127186 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| NQ150_RS25810 (127183) | 127183..128516 | + | 1334 | Protein_160 | L-lysine N6-monooxygenase | VF |
| NQ150_RS25815 (128542) | 128542..130743 | + | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| NQ150_RS25820 (131123) | 131123..131820 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| NQ150_RS25825 (132000) | 132000..132513 | - | 514 | Protein_163 | DUF4113 domain-containing protein | - |
| NQ150_RS25830 (132574) | 132574..132678 | - | 105 | Protein_164 | AAA family ATPase | - |
| NQ150_RS25835 (132680) | 132680..133003 | - | 324 | Protein_165 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|