MGE detailed information
MGE type: Conjugative plasmid MGE length: 132824 bp
Accession: NZ_CP103545 Location: 1..132824 Organism: Escherichia coli strain 3036 Replicon: plasmid pMB9029_1
Accession: NZ_CP103545 Location: 1..132824 Organism: Escherichia coli strain 3036 Replicon: plasmid pMB9029_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5S54_RS22935 (1) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| M5S54_RS22940 (1263) | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| M5S54_RS22945 (2124) | 2124..2312 | - | 189 | WP_001312821.1 | hypothetical protein | - |
| M5S54_RS22950 (2686) | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| M5S54_RS22955 (3657) | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| M5S54_RS22960 (5199) | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| M5S54_RS22965 (7449) | 7449..7628 | - | 180 | Protein_6 | transposase | - |
| M5S54_RS22970 (7767) | 7767..8980 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| M5S54_RS22975 (9128) | 9128..9396 | - | 269 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| M5S54_RS22980 (9453) | 9453..10150 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| M5S54_RS22985 (10167) | 10167..10364 | - | 198 | Protein_10 | colicin V | - |
| M5S54_RS22990 (10342) | 10342..10578 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| M5S54_RS22995 (11120) | 11120..11323 | - | 204 | Protein_12 | hypothetical protein | - |
| M5S54_RS23000 (11496) | 11496..11663 | + | 168 | Protein_13 | colicin-B | - |
| M5S54_RS23005 (11681) | 11681..12208 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| M5S54_RS23010 (12452) | 12452..13267 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| M5S54_RS23015 (13317) | 13317..13670 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| M5S54_RS23020 (13848) | 13848..14657 | - | 810 | WP_060588703.1 | site-specific integrase | - |
| M5S54_RS23025 (14658) | 14658..14963 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| M5S54_RS23030 (14965) | 14965..15183 | - | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| M5S54_RS23035 (15752) | 15752..16840 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| M5S54_RS23040 (16842) | 16842..19067 | + | 2226 | WP_000698737.1 | P-loop NTPase fold protein | - |
| M5S54_RS23045 (19117) | 19117..20016 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| M5S54_RS23050 (20006) | 20006..20296 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| M5S54_RS23055 (20592) | 20592..20822 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M5S54_RS23060 (20819) | 20819..21235 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M5S54_RS23065 (21397) | 21397..23535 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| M5S54_RS23070 (23889) | 23889..24146 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| M5S54_RS23075 (24146) | 24146..24736 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| M5S54_RS23080 (24999) | 24999..26459 | + | 1461 | WP_202745975.1 | AAA family ATPase | - |
| M5S54_RS23085 (26747) | 26747..27364 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| M5S54_RS23090 (27762) | 27762..29024 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| M5S54_RS23095 (29280) | 29280..30155 | + | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| M5S54_RS23100 (30202) | 30202..30495 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| M5S54_RS23105 (30712) | 30712..31791 | - | 1080 | WP_001089727.1 | permease | - |
| M5S54_RS23110 (31896) | 31896..32219 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| M5S54_RS23115 (32380) | 32380..32700 | + | 321 | Protein_36 | NAD(P)H-dependent oxidoreductase | - |
| M5S54_RS23120 (32753) | 32753..33457 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| M5S54_RS23125 (33523) | 33523..35037 | + | 1515 | Protein_38 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5S54_RS23130 (35095) | 35095..35337 | + | 243 | WP_000844627.1 | transposase | - |
| M5S54_RS23135 (35369) | 35369..36019 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| M5S54_RS23140 (36125) | 36125..37324 | + | 1200 | WP_077248803.1 | Tetracycline resistance protein, class C | ARG |
| M5S54_RS23145 (37356) | 37356..38240 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| M5S54_RS23150 (38378) | 38378..38770 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| M5S54_RS23155 (38774) | 38774..40354 | + | 1581 | Protein_44 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5S54_RS23160 (40405) | 40405..41109 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| M5S54_RS23165 (41175) | 41175..41459 | + | 285 | Protein_46 | IS6 family transposase IS26 | Transposase |
| M5S54_RS23170 (41603) | 41603..42244 | - | 642 | WP_001011939.1 | Chloramphenicol acetyltransferase 2 | ARG |
| M5S54_RS23175 (42394) | 42394..42894 | - | 501 | WP_001239317.1 | hypothetical protein | - |
| M5S54_RS23180 (42974) | 42974..43678 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S54_RS23185 (43733) | 43733..43990 | + | 258 | Protein_50 | hypothetical protein | - |
| M5S54_RS23190 (44136) | 44136..44999 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| M5S54_RS23195 (45037) | 45037..45282 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| M5S54_RS23200 (45751) | 45751..46542 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| M5S54_RS23205 (46545) | 46545..46820 | - | 276 | WP_109023896.1 | hypothetical protein | - |
| M5S54_RS23210 (46843) | 46843..47475 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| M5S54_RS23215 (47722) | 47722..48054 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| M5S54_RS23220 (48177) | 48177..49015 | - | 839 | Protein_57 | Streptomycin 3''-adenylyltransferase | ARG |
| M5S54_RS23225 (49104) | 49104..49994 | - | 891 | WP_223151485.1 | alpha/beta fold putative hydrolase EstX | - |
| M5S54_RS23230 (50411) | 50411..51904 | - | 1494 | WP_015344975.1 | IS91 family transposase ISVsa3 | Transposase |
| M5S54_RS23235 (52016) | 52016..52321 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator HdfR | VF |
| M5S54_RS23240 (52349) | 52349..53563 | - | 1215 | WP_000214122.1 | Bicyclomycin resistance protein | ARG |
| M5S54_RS23245 (53780) | 53780..54664 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| M5S54_RS23250 (54695) | 54695..55201 | - | 507 | Protein_63 | transposase | - |
| M5S54_RS23255 (55266) | 55266..55970 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S54_RS23260 (56017) | 56017..58317 | + | 2301 | Protein_65 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M5S54_RS23265 (58394) | 58394..59098 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S54_RS23270 (59152) | 59152..60200 | - | 1049 | Protein_67 | IS3 family transposase ISKpn11 | Transposase |
| M5S54_RS23275 (60292) | 60292..60834 | - | 543 | WP_002063889.1 | AAA family ATPase | - |
| M5S54_RS23280 (60847) | 60847..61707 | - | 861 | WP_000557452.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| M5S54_RS23285 (61814) | 61814..62518 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S54_RS23290 (62584) | 62584..63129 | + | 546 | Protein_71 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M5S54_RS23295 (63165) | 63165..63580 | - | 416 | Protein_72 | IS1 family transposase | - |
| M5S54_RS23300 (63829) | 63829..64230 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| M5S54_RS23305 (64163) | 64163..64420 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| M5S54_RS23310 (64513) | 64513..65166 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| M5S54_RS23315 (65264) | 65264..65404 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| M5S54_RS23320 (66105) | 66105..66962 | - | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| M5S54_RS23325 (66955) | 66955..67437 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| M5S54_RS23330 (67430) | 67430..67477 | - | 48 | WP_229471593.1 | hypothetical protein | - |
| M5S54_RS23335 (67468) | 67468..67719 | + | 252 | WP_223195197.1 | replication protein RepA | - |
| M5S54_RS23340 (67736) | 67736..67993 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| M5S54_RS23345 (68277) | 68277..68426 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (68470) | 68470..68531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (68470) | 68470..68531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (68470) | 68470..68531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - (68470) | 68470..68531 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| M5S54_RS23350 (68787) | 68787..68861 | - | 75 | Protein_83 | endonuclease | - |
| M5S54_RS23355 (69107) | 69107..69319 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| M5S54_RS23360 (69455) | 69455..70015 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| M5S54_RS23365 (70118) | 70118..70978 | - | 861 | WP_000704513.1 | Quorum-quenching protein AidA | VF |
| M5S54_RS23370 (71037) | 71037..71783 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| M5S54_RS23375 (71803) | 71803..77073 | - | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| M5S54_RS23380 (77155) | 77155..77382 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| M5S54_RS23385 (77382) | 77382..77780 | + | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M5S54_RS23390 (77789) | 77789..79951 | - | 2163 | WP_023352413.1 | type IV conjugative transfer system coupling protein TraD | - |
| M5S54_RS23395 (80204) | 80204..80935 | - | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| M5S54_RS23400 (80967) | 80967..81464 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| M5S54_RS23405 (81480) | 81480..84302 | - | 2823 | WP_001007018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| M5S54_RS23410 (84299) | 84299..85672 | - | 1374 | WP_001517790.1 | conjugal transfer pilus assembly protein TraH | - |
| M5S54_RS23415 (85672) | 85672..86052 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| M5S54_RS23420 (86039) | 86039..86380 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| M5S54_RS23425 (86310) | 86310..86855 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M5S54_RS23430 (86842) | 86842..87126 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M5S54_RS23435 (87207) | 87207..87521 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| M5S54_RS23440 (87523) | 87523..87870 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| M5S54_RS23445 (87886) | 87886..88629 | - | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| M5S54_RS23450 (88622) | 88622..88879 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| M5S54_RS23455 (88906) | 88906..90714 | - | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| M5S54_RS23460 (90711) | 90711..91349 | - | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| M5S54_RS23465 (91358) | 91358..92350 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| M5S54_RS23470 (92347) | 92347..92979 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| M5S54_RS23475 (92976) | 92976..93362 | - | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| M5S54_RS23480 (93359) | 93359..95986 | - | 2628 | WP_259418792.1 | type IV secretion system protein TraC | - |
| M5S54_RS23485 (96146) | 96146..96367 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| M5S54_RS23490 (96502) | 96502..97017 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M5S54_RS23495 (97014) | 97014..97265 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| M5S54_RS23500 (97277) | 97277..97474 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| M5S54_RS23505 (97461) | 97461..98051 | - | 591 | WP_001376242.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| M5S54_RS23510 (98041) | 98041..99468 | - | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M5S54_RS23515 (99468) | 99468..100196 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| M5S54_RS23520 (100183) | 100183..100749 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| M5S54_RS23530 (101562) | 101562..101858 | - | 297 | WP_259418793.1 | type IV conjugative transfer system protein TraL | - |
| M5S54_RS23535 (101873) | 101873..102238 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| M5S54_RS23540 (102271) | 102271..102672 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| M5S54_RS23545 (102765) | 102765..103454 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| M5S54_RS23550 (103641) | 103641..104024 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M5S54_RS23555 (104345) | 104345..104947 | + | 603 | WP_072156291.1 | hypothetical protein | VF |
| M5S54_RS23560 (105244) | 105244..106065 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| M5S54_RS23565 (106184) | 106184..106471 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| M5S54_RS23570 (106496) | 106496..106702 | - | 207 | WP_000547971.1 | hypothetical protein | - |
| M5S54_RS23575 (106772) | 106772..106945 | + | 174 | Protein_128 | hypothetical protein | - |
| M5S54_RS23580 (106943) | 106943..107173 | - | 231 | WP_001426396.1 | hypothetical protein | - |
| M5S54_RS23585 (107393) | 107393..107518 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| M5S54_RS23590 (107460) | 107460..107609 | - | 150 | Protein_131 | plasmid maintenance protein Mok | - |
| - (107595) | 107595..107819 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (107595) | 107595..107819 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (107595) | 107595..107819 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (107595) | 107595..107819 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| M5S54_RS23595 (107631) | 107631..107819 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| M5S54_RS23600 (107788) | 107788..108550 | - | 763 | Protein_133 | plasmid SOS inhibition protein A | - |
| M5S54_RS23605 (108547) | 108547..108981 | - | 435 | WP_064770609.1 | conjugation system SOS inhibitor PsiB | - |
| M5S54_RS23610 (109036) | 109036..109233 | - | 198 | Protein_135 | hypothetical protein | - |
| M5S54_RS23615 (109261) | 109261..109494 | - | 234 | WP_000005987.1 | DUF905 family protein | - |
| M5S54_RS23620 (109562) | 109562..110101 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| M5S54_RS23625 (110127) | 110127..110333 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| M5S54_RS23630 (110403) | 110403..110483 | + | 81 | Protein_139 | hypothetical protein | - |
| M5S54_RS23635 (110666) | 110666..110835 | - | 170 | Protein_140 | hypothetical protein | - |
| M5S54_RS23640 (111472) | 111472..112443 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5S54_RS23645 (112443) | 112443..113609 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| M5S54_RS23655 (115091) | 115091..117292 | - | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| M5S54_RS23660 (117318) | 117318..118651 | - | 1334 | Protein_145 | L-lysine N6-monooxygenase | VF |
| M5S54_RS23665 (118648) | 118648..120390 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| M5S54_RS23670 (120390) | 120390..121337 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| M5S54_RS23675 (121338) | 121338..123062 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| M5S54_RS23680 (123198) | 123198..124391 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| M5S54_RS23685 (124771) | 124771..125151 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| M5S54_RS23690 (125492) | 125492..125905 | - | 414 | Protein_151 | phosphopyruvate hydratase | - |
| M5S54_RS23695 (125903) | 125903..126160 | + | 258 | Protein_152 | transposase | - |
| M5S54_RS23700 (126394) | 126394..127251 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| M5S54_RS23705 (127248) | 127248..128105 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| M5S54_RS23710 (128102) | 128102..128929 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| M5S54_RS23715 (128929) | 128929..129843 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| M5S54_RS23720 (130199) | 130199..130896 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| M5S54_RS23725 (131076) | 131076..131589 | - | 514 | Protein_158 | DUF4113 domain-containing protein | - |
| M5S54_RS23730 (131650) | 131650..131754 | - | 105 | Protein_159 | AAA family ATPase | - |
| M5S54_RS23735 (131756) | 131756..132079 | - | 324 | Protein_160 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|