MGE detailed information
MGE type: Conjugative plasmid MGE length: 125297 bp
Accession: NZ_CP102548 Location: 1..125297 Organism: Klebsiella pneumoniae strain KPH1 Replicon: plasmid p2
Accession: NZ_CP102548 Location: 1..125297 Organism: Klebsiella pneumoniae strain KPH1 Replicon: plasmid p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NUG47_RS26875 (1) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| NUG47_RS26880 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| NUG47_RS26885 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| NUG47_RS26890 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NUG47_RS26895 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| NUG47_RS26900 (3449) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| NUG47_RS26905 (4651) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| NUG47_RS26910 (4814) | 4814..5107 | - | 294 | WP_001105060.1 | hypothetical protein | - |
| NUG47_RS26915 (5213) | 5213..5488 | - | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| NUG47_RS26920 (5488) | 5488..5772 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| NUG47_RS26925 (6426) | 6426..7123 | + | 698 | WP_151884388.1 | IS1 family transposase IS1X2 | Transposase |
| NUG47_RS26930 (7138) | 7138..8301 | + | 1164 | Protein_11 | IS4 family transposase IS10R | Transposase |
| NUG47_RS26935 (8311) | 8311..8727 | - | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| NUG47_RS26940 (8815) | 8815..9408 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| NUG47_RS26945 (9521) | 9521..10726 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| NUG47_RS26950 (10808) | 10808..11431 | + | 624 | WP_168799663.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| NUG47_RS26955 (11409) | 11409..12095 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| NUG47_RS26960 (12103) | 12103..12489 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| NUG47_RS26965 (12482) | 12482..12745 | - | 264 | WP_049802299.1 | antibiotic biosynthesis monooxygenase | - |
| NUG47_RS26975 (13494) | 13494..13769 | + | 276 | Protein_20 | CatA-like O-acetyltransferase | - |
| NUG47_RS26980 (13970) | 13970..14347 | - | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| NUG47_RS26985 (14414) | 14414..17380 | - | 2967 | WP_257796700.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| NUG47_RS26990 (17383) | 17383..17943 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| NUG47_RS26995 (18069) | 18069..18419 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| NUG47_RS27000 (18622) | 18622..19635 | - | 1014 | WP_000845039.1 | IS91 family transposase ISAzo26 | Transposase |
| NUG47_RS27005 (19780) | 19780..20277 | + | 498 | WP_001083725.1 | IS1595 family transposase ISSsu9 | ARG |
| NUG47_RS27010 (20389) | 20389..20679 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| NUG47_RS27015 (20685) | 20685..21523 | + | 839 | Protein_28 | Streptomycin 3''-adenylyltransferase | ARG |
| NUG47_RS27020 (21640) | 21640..21987 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| NUG47_RS27025 (21981) | 21981..22820 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| NUG47_RS27030 (23225) | 23225..24766 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| NUG47_RS27035 (25079) | 25079..25453 | + | 375 | Protein_32 | protein-disulfide reductase DsbD family protein | - |
| NUG47_RS27040 (25553) | 25553..26110 | + | 558 | Protein_33 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| NUG47_RS27045 (26121) | 26121..26759 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| NUG47_RS27050 (26764) | 26764..27129 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| NUG47_RS27055 (27133) | 27133..27945 | - | 813 | WP_004201164.1 | Metallo-beta-lactamase type 2 | ARG |
| NUG47_RS27060 (28046) | 28046..28339 | - | 294 | Protein_37 | IS30 family transposase ISAba125 | Transposase |
| NUG47_RS27065 (28504) | 28504..29208 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NUG47_RS27070 (29274) | 29274..29819 | + | 546 | Protein_39 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NUG47_RS27075 (29855) | 29855..30270 | - | 416 | Protein_40 | IS1 family transposase | - |
| NUG47_RS27080 (30519) | 30519..30920 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NUG47_RS27085 (30853) | 30853..31110 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NUG47_RS27090 (31203) | 31203..31856 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NUG47_RS27095 (32780) | 32780..35797 | + | 3018 | WP_004199413.1 | Tn3 family transposase TnpA_IS3000 | Transposase |
| NUG47_RS27100 (36036) | 36036..36893 | - | 858 | WP_000130948.1 | incFII family plasmid replication initiator RepA | - |
| NUG47_RS27105 (36886) | 36886..36960 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| NUG47_RS27110 (37196) | 37196..37453 | - | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| NUG47_RS27115 (37858) | 37858..38880 | + | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| NUG47_RS27120 (39352) | 39352..39705 | + | 354 | WP_000005489.1 | hypothetical protein | - |
| NUG47_RS27125 (40118) | 40118..40696 | - | 579 | WP_032147503.1 | DUF2726 domain-containing protein | - |
| NUG47_RS27130 (40729) | 40729..41426 | + | 698 | WP_250164203.1 | IS1-like element IS1B family transposase | - |
| NUG47_RS27135 (41541) | 41541..41897 | + | 357 | WP_000229735.1 | IS66 family transposase ISEc23 | Transposase |
| NUG47_RS27140 (41894) | 41894..42244 | + | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| NUG47_RS27145 (42275) | 42275..42496 | + | 222 | WP_000080217.1 | IS66 family transposase ISEc47 | Transposase |
| NUG47_RS27150 (42448) | 42448..42789 | + | 342 | Protein_55 | transposase | - |
| NUG47_RS27155 (42853) | 42853..43332 | - | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| NUG47_RS27160 (43413) | 43413..44816 | - | 1404 | WP_000514417.1 | YfcC family protein | - |
| NUG47_RS27165 (44864) | 44864..45868 | - | 1005 | WP_000154544.1 | Ornithine carbamoyltransferase | VF |
| NUG47_RS27170 (45953) | 45953..46864 | - | 912 | WP_000440183.1 | carbamate kinase | - |
| NUG47_RS27175 (46875) | 46875..48095 | - | 1221 | WP_000410951.1 | arginine deiminase | - |
| NUG47_RS27180 (48829) | 48829..49416 | + | 588 | Protein_61 | VENN motif pre-toxin domain-containing protein | - |
| NUG47_RS27185 (49416) | 49416..49862 | - | 447 | Protein_62 | plasmid replication initiator RepA | - |
| NUG47_RS27190 (49855) | 49855..49929 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| NUG47_RS27195 (50165) | 50165..50422 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| NUG47_RS27200 (50706) | 50706..50855 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (50899) | 50899..50960 | + | 62 | NuclAT_1 | - | - |
| - (50899) | 50899..50960 | + | 62 | NuclAT_1 | - | - |
| - (50899) | 50899..50960 | + | 62 | NuclAT_1 | - | - |
| - (50899) | 50899..50960 | + | 62 | NuclAT_1 | - | - |
| NUG47_RS27205 (51099) | 51099..51281 | - | 183 | WP_000968309.1 | hypothetical protein | - |
| NUG47_RS27210 (51382) | 51382..52088 | + | 707 | WP_228719446.1 | IS1 family transposase | - |
| NUG47_RS27215 (52389) | 52389..52601 | - | 213 | WP_005012601.1 | hypothetical protein | - |
| NUG47_RS27220 (52734) | 52734..53294 | - | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| NUG47_RS27225 (53349) | 53349..54095 | - | 747 | WP_094083868.1 | conjugal transfer pilus acetylase TraX | - |
| NUG47_RS27230 (54115) | 54115..55305 | - | 1191 | Protein_71 | Multifunctional conjugation protein TraI | Relaxase |
| NUG47_RS27235 (55410) | 55410..56042 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| NUG47_RS27240 (56039) | 56039..56425 | - | 387 | WP_000099690.1 | type-F conjugative transfer system protein TrbI | - |
| NUG47_RS27245 (56422) | 56422..59049 | - | 2628 | WP_001064264.1 | type IV secretion system protein TraC | - |
| NUG47_RS27250 (59209) | 59209..59430 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| NUG47_RS27255 (59565) | 59565..60080 | - | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NUG47_RS27260 (60077) | 60077..60328 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| NUG47_RS27265 (60321) | 60321..60641 | - | 321 | Protein_78 | conjugal transfer protein TrbD | - |
| NUG47_RS27270 (60628) | 60628..61155 | - | 528 | WP_005012539.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NUG47_RS27275 (61199) | 61199..61765 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| NUG47_RS27280 (61787) | 61787..62098 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NUG47_RS27285 (62113) | 62113..62478 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| NUG47_RS27290 (62521) | 62521..62736 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| NUG47_RS27295 (62872) | 62872..63519 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| NUG47_RS27300 (63710) | 63710..64093 | - | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NUG47_RS27305 (64463) | 64463..65035 | + | 573 | WP_000949660.1 | hypothetical protein | VF |
| NUG47_RS27310 (65331) | 65331..66152 | - | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
| NUG47_RS27315 (66271) | 66271..66558 | - | 288 | Protein_88 | hypothetical protein | - |
| NUG47_RS27320 (66583) | 66583..66789 | - | 207 | WP_000275854.1 | hypothetical protein | - |
| NUG47_RS27325 (66859) | 66859..67156 | + | 298 | Protein_90 | hypothetical protein | - |
| NUG47_RS27330 (67457) | 67457..67582 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NUG47_RS27335 (67524) | 67524..67673 | - | 150 | Protein_92 | DUF5431 family protein | - |
| - (67680) | 67680..67878 | - | 199 | NuclAT_0 | - | - |
| - (67680) | 67680..67878 | - | 199 | NuclAT_0 | - | - |
| - (67680) | 67680..67878 | - | 199 | NuclAT_0 | - | - |
| - (67680) | 67680..67878 | - | 199 | NuclAT_0 | - | - |
| NUG47_RS27340 (68107) | 68107..68424 | + | 318 | Protein_93 | IS110 family transposase IS1618 | Transposase |
| NUG47_RS27345 (68713) | 68713..68964 | - | 252 | Protein_94 | iron-containing alcohol dehydrogenase | - |
| NUG47_RS27350 (69049) | 69049..69672 | - | 624 | WP_000912556.1 | ion channel | - |
| NUG47_RS27360 (70442) | 70442..70546 | + | 105 | Protein_97 | thiosulfate reductase cytochrome B subunit | - |
| NUG47_RS27365 (70792) | 70792..72186 | - | 1395 | WP_001037799.1 | carbohydrate porin | - |
| NUG47_RS27370 (72381) | 72381..73814 | - | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| NUG47_RS27375 (73811) | 73811..75088 | - | 1278 | WP_001083369.1 | MFS transporter | - |
| NUG47_RS27380 (75151) | 75151..77277 | - | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| NUG47_RS27385 (77373) | 77373..78383 | - | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| NUG47_RS27390 (78541) | 78541..79299 | - | 759 | Protein_103 | site-specific integrase | - |
| NUG47_RS27395 (79390) | 79390..80618 | + | 1229 | WP_152924612.1 | IS3 family transposase IS2 | Transposase |
| NUG47_RS27400 (80603) | 80603..81172 | + | 570 | WP_089634947.1 | hypothetical protein | - |
| NUG47_RS27405 (82103) | 82103..82372 | - | 270 | WP_071977877.1 | hypothetical protein | - |
| NUG47_RS27410 (82273) | 82273..82497 | - | 225 | WP_016238251.1 | hypothetical protein | - |
| NUG47_RS27415 (82523) | 82523..83086 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| NUG47_RS27420 (83134) | 83134..84495 | - | 1362 | WP_094307953.1 | DUF3560 domain-containing protein | - |
| NUG47_RS27425 (84547) | 84547..84777 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| NUG47_RS27430 (85812) | 85812..86003 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| NUG47_RS27435 (86000) | 86000..86422 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| NUG47_RS27440 (86469) | 86469..86894 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| NUG47_RS27445 (87311) | 87311..88087 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| NUG47_RS27450 (88138) | 88138..88656 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| NUG47_RS27455 (88586) | 88586..88807 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| NUG47_RS27460 (88808) | 88808..89491 | - | 684 | WP_000086185.1 | DNA methylase | - |
| NUG47_RS27465 (89568) | 89568..89879 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| NUG47_RS27470 (89876) | 89876..90778 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| NUG47_RS27475 (91645) | 91645..92616 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NUG47_RS27480 (92616) | 92616..93782 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| NUG47_RS27485 (94370) | 94370..95125 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| NUG47_RS27490 (95899) | 95899..96705 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| NUG47_RS27495 (96706) | 96706..97011 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| NUG47_RS27500 (97013) | 97013..97231 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| NUG47_RS27505 (97865) | 97865..98062 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| NUG47_RS27510 (98059) | 98059..98343 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| NUG47_RS27515 (98363) | 98363..99496 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| NUG47_RS27520 (99759) | 99759..102878 | - | 3120 | WP_001553851.1 | hypothetical protein | - |
| NUG47_RS27525 (103185) | 103185..103415 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| NUG47_RS27530 (103412) | 103412..103828 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NUG47_RS27535 (103990) | 103990..106128 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| NUG47_RS27540 (106593) | 106593..107588 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| NUG47_RS27545 (107631) | 107631..108524 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| NUG47_RS27555 (109572) | 109572..112688 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| NUG47_RS27560 (112810) | 112810..114081 | - | 1272 | WP_048266692.1 | restriction endonuclease subunit S | - |
| NUG47_RS27565 (114078) | 114078..114368 | - | 291 | Protein_138 | SAM-dependent methyltransferase | - |
| NUG47_RS27570 (114424) | 114424..115121 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| NUG47_RS27575 (115116) | 115116..116411 | - | 1296 | Protein_140 | type I restriction-modification system subunit M | - |
| NUG47_RS27580 (116594) | 116594..116815 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| NUG47_RS27585 (116815) | 116815..117195 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| NUG47_RS27590 (117200) | 117200..117379 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| NUG47_RS27595 (117407) | 117407..117685 | + | 279 | Protein_144 | pdcB | - |
| NUG47_RS27600 (117690) | 117690..118103 | + | 414 | Protein_145 | IS3 family transposase ISLad1 | Transposase |
| NUG47_RS27605 (118053) | 118053..118388 | - | 336 | WP_169329198.1 | type I deoxyribonuclease HsdR | - |
| NUG47_RS27610 (118598) | 118598..119578 | - | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| NUG47_RS27615 (119822) | 119822..121225 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| NUG47_RS27620 (121212) | 121212..122144 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| NUG47_RS27625 (122253) | 122253..122582 | - | 330 | Protein_150 | TOBE domain-containing protein | - |
| NUG47_RS27635 (123572) | 123572..124542 | - | 971 | Protein_152 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|