NZ_CP1017281..172348

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 172348 bp
Accession: NZ_CP101728        Location: 1..172348         Organism: Klebsiella pneumoniae strain 150040X1B1       Replicon: plasmid pVir_150040X1B1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NPN21_RS27885 (1) 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
NPN21_RS27890 (1263) 1263..2003 - 741 WP_001066954.1 tyrosine-type recombinase/integrase -
NPN21_RS27895 (2124) 2124..2312 - 189 WP_001324033.1 hypothetical protein -
NPN21_RS27900 (2686) 2686..3588 - 903 WP_001312822.1 hypothetical protein VF
NPN21_RS27905 (3657) 3657..4766 - 1110 WP_000771475.1 SDR family oxidoreductase -
NPN21_RS27910 (5199) 5199..6152 - 954 WP_000280980.1 Protease 7 VF
NPN21_RS27915 (7449) 7449..7628 - 180 Protein_6 transposase -
NPN21_RS27920 (7767) 7767..8966 + 1200 Protein_7 IS3 family transposase IS629 Transposase
NPN21_RS27925 (9114) 9114..9439 - 326 Protein_8 IS3 family transposase ISLad1 Transposase
NPN21_RS27930 (9485) 9485..9825 + 341 Protein_9 IS3 family transposase -
NPN21_RS27935 (10420) 10420..11607 + 1188 WP_000928804.1 efflux RND transporter periplasmic adaptor subunit -
NPN21_RS27940 (11604) 11604..13544 + 1941 WP_000733250.1 Macrolide export ATP-binding/permease protein MacB VF
NPN21_RS27945 (13548) 13548..14918 + 1371 WP_001312828.1 efflux transporter outer membrane subunit -
NPN21_RS27950 (15392) 15392..15586 + 195 Protein_13 IS200/IS605-like element IS200C family transposase -
NPN21_RS27955 (15715) 15715..16656 - 942 WP_000974762.1 hypothetical protein -
NPN21_RS27960 (16891) 16891..18280 - 1390 Protein_15 ISNCY family transposase ISKpn21 Transposase
NPN21_RS27965 (18590) 18590..18739 - 150 Protein_16 IS3 family transposase IS2 Transposase
NPN21_RS27970 (18917) 18917..20110 - 1194 WP_000450494.1 GTP-binding protein -
NPN21_RS27975 (21352) 21352..22089 - 738 Protein_18 IS3 family transposase IS2 Transposase
NPN21_RS27980 (22142) 22142..23304 + 1163 WP_088846059.1 IS3 family transposase ISEc17 Transposase
NPN21_RS27985 (23321) 23321..23841 - 521 Protein_20 IS3 family transposase IS2 Transposase
NPN21_RS27990 (24466) 24466..24759 + 294 WP_000738422.1 increased serum survival lipoprotein Iss -
NPN21_RS27995 (24843) 24843..24991 - 149 Protein_22 Rz1 family lipoprotein -
NPN21_RS28000 (24948) 24948..25055 - 108 Protein_23 lysis protein -
NPN21_RS28005 (25570) 25570..26594 + 1025 Protein_24 integrase core domain-containing protein -
NPN21_RS28010 (27905) 27905..29020 + 1116 WP_001318220.1 Elloramycin glycosyltransferase ElmGT VF
NPN21_RS28015 (29160) 29160..32819 + 3660 WP_001389363.1 Multidrug efflux ATP-binding/permease protein VF
NPN21_RS28020 (32923) 32923..34152 + 1230 WP_000933678.1 Enterochelin esterase VF
NPN21_RS28025 (34237) 34237..35193 + 957 WP_000271274.1 hypothetical protein VF
NPN21_RS28030 (35238) 35238..37415 - 2178 WP_001222185.1 Ferric enterobactin receptor VF
NPN21_RS28035 (38281) 38281..39315 - 1035 WP_001190234.1 3-deoxy-7-phosphoheptulonate synthase -
NPN21_RS28040 (39496) 39496..39797 + 302 Protein_31 hypothetical protein -
NPN21_RS28045 (39875) 39875..40183 - 309 WP_000377483.1 DUF6404 family protein -
NPN21_RS28050 (40336) 40336..40461 - 126 Protein_33 type II toxin-antitoxin system toxin YacB -
NPN21_RS28055 (40461) 40461..40729 - 269 Protein_34 type II toxin-antitoxin system antitoxin YacA -
NPN21_RS28060 (41340) 41340..42614 + 1275 WP_000489609.1 HlyD family secretion protein -
NPN21_RS28065 (42607) 42607..43158 + 552 Protein_36 cysteine peptidase family C39 domain-containing protein -
NPN21_RS28075 (44414) 44414..45964 + 1551 Protein_38 Toxin RTX-I translocation ATP-binding protein VF
NPN21_RS28080 (46134) 46134..46445 - 312 WP_001259758.1 colicin V -
NPN21_RS28085 (46423) 46423..46659 - 237 WP_001323890.1 colicin V immunity protein -
NPN21_RS28090 (46778) 46778..47221 + 444 WP_001323891.1 dehydrogenase -
NPN21_RS28095 (47193) 47193..47597 + 405 WP_001389361.1 hypothetical protein -
NPN21_RS28100 (47599) 47599..47868 + 270 WP_000379710.1 SemiSWEET transporter -
NPN21_RS28105 (47865) 47865..48845 + 981 WP_001017346.1 NAD(P)-binding domain-containing protein -
NPN21_RS28110 (48921) 48921..49301 + 381 WP_001171523.1 IS66 family transposase ISEc8 Transposase
NPN21_RS28115 (49298) 49298..49645 + 348 WP_000612591.1 IS66 family transposase ISEc8 Transposase
NPN21_RS28120 (49695) 49695..51232 + 1538 Protein_47 IS66 family transposase ISEc8 Transposase
NPN21_RS28125 (51272) 51272..51538 + 267 Protein_48 Tn3 family transposase TnpR_TnEc1 Transposase
NPN21_RS28130 (51585) 51585..51977 - 393 Protein_49 peptide deformylase -
NPN21_RS28135 (52086) 52086..56219 - 4134 WP_001080137.1 Temperature-sensitive hemagglutinin tsh autotransporter VF
NPN21_RS28140 (56390) 56390..56581 + 192 Protein_51 IS91 family transposase -
NPN21_RS28145 (56860) 56860..57117 + 258 Protein_52 IS3 family transposase IS911 Transposase
NPN21_RS28150 (57185) 57185..58336 + 1152 WP_001442799.1 IS30 family transposase IS30D Transposase
NPN21_RS28155 (58458) 58458..58823 + 366 WP_000124098.1 hypothetical protein -
NPN21_RS28160 (58823) 58823..59938 + 1116 Protein_55 IS91 family transposase IS91 Transposase
NPN21_RS28165 (60119) 60119..60463 - 345 WP_001553768.1 hypothetical protein -
NPN21_RS28170 (61321) 61321..63072 - 1752 Protein_57 Tn3 family transposase TnpA_TnAs1 Transposase
NPN21_RS28175 (63076) 63076..63468 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
NPN21_RS28180 (63606) 63606..64490 + 885 WP_000058717.1 EamA family transporter -
NPN21_RS28185 (64522) 64522..65721 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
NPN21_RS28190 (65827) 65827..66477 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
NPN21_RS28195 (66509) 66509..66751 - 243 WP_000844627.1 transposase -
NPN21_RS28200 (66809) 66809..68323 - 1515 Protein_63 Tn3 family transposase TnpA_TnAs1 Transposase
NPN21_RS28205 (68389) 68389..69093 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS28210 (69541) 69541..70554 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
NPN21_RS28215 (70710) 70710..71183 + 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
NPN21_RS28220 (71253) 71253..71957 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NPN21_RS28225 (72011) 72011..72325 + 315 Protein_68 Tn3 family transposase TnpR_TnAs3 Transposase
NPN21_RS28230 (72328) 72328..75294 + 2967 WP_001138070.1 Tn3 family transposase TnpA_ISPa38 Transposase
NPN21_RS28235 (75373) 75373..76377 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
NPN21_RS28240 (76649) 76649..76735 - 87 Protein_71 Arm DNA-binding domain-containing protein -
NPN21_RS28245 (77065) 77065..77880 + 816 WP_001043260.1 Dihydropteroate synthase ARG
NPN21_RS28250 (77941) 77941..78744 + 804 WP_001082320.1 Aminoglycoside 3'-phosphotransferase ARG
NPN21_RS28255 (78744) 78744..79580 + 837 WP_000480972.1 hypothetical protein ARG
NPN21_RS28260 (79811) 79811..80671 - 861 WP_000027057.1 Beta-lactamase TEM ARG
NPN21_RS28265 (80854) 80854..81411 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
NPN21_RS28270 (81575) 81575..84580 + 3006 WP_256153266.1 Tn3 family transposase TnpA_Tn3 Transposase
NPN21_RS28275 (84513) 84513..84978 - 466 Protein_78 plasmid replication initiator RepA -
NPN21_RS28280 (84971) 84971..85453 - 483 WP_001273588.1 hypothetical protein -
NPN21_RS28285 (85446) 85446..85493 - 48 WP_229471593.1 hypothetical protein -
NPN21_RS28290 (85484) 85484..85735 + 252 WP_223195197.1 replication protein RepA -
NPN21_RS28295 (85752) 85752..86009 - 258 WP_000083845.1 replication regulatory protein RepA -
NPN21_RS28300 (86293) 86293..86442 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (86486) 86486..86547 + 62 NuclAT_1 - Antitoxin Detail
- (86486) 86486..86547 + 62 NuclAT_1 - Antitoxin Detail
- (86486) 86486..86547 + 62 NuclAT_1 - Antitoxin Detail
- (86486) 86486..86547 + 62 NuclAT_1 - Antitoxin Detail
NPN21_RS28305 (86803) 86803..86877 - 75 Protein_84 endonuclease -
NPN21_RS28310 (87123) 87123..87335 - 213 WP_001299730.1 ANR family transcriptional regulator -
NPN21_RS28315 (87471) 87471..88031 - 561 WP_000139315.1 fertility inhibition protein FinO -
NPN21_RS28320 (88134) 88134..88994 - 861 WP_000704513.1 Quorum-quenching protein AidA VF
NPN21_RS28325 (89053) 89053..89799 - 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
NPN21_RS28330 (89819) 89819..95089 - 5271 WP_256153267.1 Multifunctional conjugation protein TraI Relaxase
NPN21_RS28335 (95171) 95171..95398 + 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
NPN21_RS28340 (95398) 95398..95796 + 399 WP_000911313.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NPN21_RS28345 (95805) 95805..97958 - 2154 WP_000009324.1 type IV conjugative transfer system coupling protein TraD -
NPN21_RS28350 (98211) 98211..98942 - 732 WP_023565183.1 conjugal transfer complement resistance protein TraT -
NPN21_RS28355 (98974) 98974..99471 - 498 WP_000605857.1 entry exclusion protein -
NPN21_RS28360 (99487) 99487..102309 - 2823 WP_001007018.1 conjugal transfer mating-pair stabilization protein TraG -
NPN21_RS28365 (102306) 102306..103682 - 1377 WP_000982840.1 conjugal transfer pilus assembly protein TraH -
NPN21_RS28370 (103679) 103679..104059 - 381 WP_001389370.1 F-type conjugal transfer protein TrbF -
NPN21_RS28375 (104046) 104046..104387 - 342 WP_001443031.1 P-type conjugative transfer protein TrbJ -
NPN21_RS28380 (104317) 104317..104862 - 546 WP_000059851.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
NPN21_RS28385 (104849) 104849..105133 - 285 WP_000624109.1 type-F conjugative transfer system pilin chaperone TraQ -
NPN21_RS28390 (105214) 105214..105528 + 315 WP_001324103.1 hypothetical protein -
NPN21_RS28395 (105530) 105530..105877 - 348 WP_001287910.1 conjugal transfer protein TrbA -
NPN21_RS28400 (105893) 105893..106642 - 750 WP_001324102.1 type-F conjugative transfer system pilin assembly protein TraF -
NPN21_RS28405 (106629) 106629..106886 - 258 WP_000864318.1 conjugal transfer protein TrbE -
NPN21_RS28410 (106913) 106913..108721 - 1809 WP_000821838.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
NPN21_RS28415 (108718) 108718..109356 - 639 WP_000777695.1 type-F conjugative transfer system pilin assembly protein TrbC -
NPN21_RS28420 (109365) 109365..110357 - 993 WP_000830183.1 conjugal transfer pilus assembly protein TraU -
NPN21_RS28425 (110354) 110354..110986 - 633 WP_001203717.1 type-F conjugative transfer system protein TraW -
NPN21_RS28430 (110983) 110983..111369 - 387 WP_000099691.1 type-F conjugative transfer system protein TrbI -
NPN21_RS28435 (111366) 111366..113993 - 2628 WP_001064245.1 type IV secretion system protein TraC -
NPN21_RS28440 (114153) 114153..114374 - 222 WP_001278689.1 conjugal transfer protein TraR -
NPN21_RS28445 (114509) 114509..115024 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
NPN21_RS28450 (115021) 115021..115272 - 252 WP_001038342.1 conjugal transfer protein TrbG -
NPN21_RS28455 (115284) 115284..115481 - 198 WP_024179215.1 conjugal transfer protein TrbD -
NPN21_RS28460 (115468) 115468..116058 - 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
NPN21_RS28465 (116048) 116048..117475 - 1428 WP_219391523.1 F-type conjugal transfer pilus assembly protein TraB -
NPN21_RS28470 (117475) 117475..118203 - 729 WP_001230813.1 type-F conjugative transfer system secretin TraK -
NPN21_RS28475 (118190) 118190..118756 - 567 WP_000399790.1 type IV conjugative transfer system protein TraE -
NPN21_RS28480 (118778) 118778..119089 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
NPN21_RS28485 (119104) 119104..119469 - 366 WP_021518377.1 type IV conjugative transfer system pilin TraA -
NPN21_RS28490 (119512) 119512..119727 - 216 WP_001352842.1 conjugal transfer relaxosome protein TraY -
NPN21_RS28495 (119863) 119863..120510 - 648 WP_000332520.1 conjugal transfer transcriptional regulator TraJ -
NPN21_RS28500 (120702) 120702..121085 - 384 WP_001063020.1 conjugal transfer relaxosome DNA-binding protein TraM -
NPN21_RS28505 (121437) 121437..122027 + 591 WP_166494936.1 hypothetical protein VF
NPN21_RS28510 (122322) 122322..123143 - 822 WP_001234475.1 DUF932 domain-containing protein -
NPN21_RS28515 (123262) 123262..123549 - 288 WP_000107546.1 hypothetical protein -
NPN21_RS28520 (123574) 123574..123780 - 207 WP_000547965.1 hypothetical protein -
NPN21_RS28525 (123850) 123850..124146 + 297 Protein_128 hypothetical protein -
NPN21_RS28530 (124447) 124447..124572 - 126 WP_096937776.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
NPN21_RS28535 (124514) 124514..124663 - 150 Protein_130 DUF5431 family protein -
- (124670) 124670..124868 - 199 NuclAT_0 - Antitoxin Detail
- (124670) 124670..124868 - 199 NuclAT_0 - Antitoxin Detail
- (124670) 124670..124868 - 199 NuclAT_0 - Antitoxin Detail
- (124670) 124670..124868 - 199 NuclAT_0 - Antitoxin Detail
NPN21_RS28540 (124837) 124837..125599 - 763 Protein_131 plasmid SOS inhibition protein A -
NPN21_RS28545 (125596) 125596..126030 - 435 WP_000845928.1 conjugation system SOS inhibitor PsiB -
NPN21_RS28550 (126085) 126085..128043 - 1959 WP_029487628.1 ParB/RepB/Spo0J family partition protein -
NPN21_RS28555 (128109) 128109..128342 - 234 WP_000005990.1 DUF905 family protein -
NPN21_RS28560 (128399) 128399..128938 - 540 WP_000290801.1 single-stranded DNA-binding protein -
NPN21_RS28565 (129735) 129735..129926 - 192 WP_001027495.1 hypothetical protein -
NPN21_RS28570 (129923) 129923..130345 - 423 WP_000271685.1 DUF1380 family protein -
NPN21_RS28575 (130392) 130392..130817 - 426 WP_001198918.1 antirestriction protein -
NPN21_RS28580 (131230) 131230..132006 - 777 WP_001005035.1 hypothetical protein -
NPN21_RS28585 (132052) 132052..132606 - 555 WP_077248347.1 DUF1380 family protein -
NPN21_RS28590 (132500) 132500..132721 - 222 WP_001104870.1 hypothetical protein -
NPN21_RS28595 (132722) 132722..133405 - 684 WP_000085939.1 DNA methylase -
NPN21_RS28600 (133482) 133482..133787 - 306 WP_010891292.1 hypothetical protein -
NPN21_RS28605 (133791) 133791..134692 - 902 Protein_144 DUF1281 domain-containing protein -
NPN21_RS28610 (135602) 135602..136573 - 972 WP_000817035.1 ParB/RepB/Spo0J family plasmid partition protein -
NPN21_RS28615 (136573) 136573..137739 - 1167 WP_000772446.1 hypothetical protein VF
NPN21_RS28620 (138327) 138327..139082 - 756 WP_000852146.1 replication initiation protein RepE -
NPN21_RS28625 (139834) 139834..140640 - 807 WP_000016982.1 site-specific integrase -
NPN21_RS28630 (140641) 140641..140946 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
NPN21_RS28635 (140948) 140948..141166 - 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
NPN21_RS28640 (141758) 141758..142246 + 489 WP_011254646.1 hypothetical protein -
NPN21_RS28645 (142280) 142280..143413 - 1134 WP_000545984.1 DUF3800 domain-containing protein -
NPN21_RS28650 (143580) 143580..144353 - 774 WP_000905949.1 hypothetical protein -
NPN21_RS28655 (144366) 144366..144866 - 501 WP_000528932.1 HEPN family nuclease -
NPN21_RS28660 (145131) 145131..145361 + 231 WP_001261278.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
NPN21_RS28665 (145358) 145358..145774 + 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NPN21_RS28670 (145819) 145819..149613 - 3795 WP_001144731.1 hypothetical protein -
NPN21_RS28675 (149994) 149994..150224 + 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
NPN21_RS28680 (150221) 150221..150637 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NPN21_RS28685 (150712) 150712..152277 + 1566 WP_001128474.1 AAA family ATPase -
NPN21_RS28690 (152262) 152262..153284 + 1023 WP_000361402.1 helicase UvrD -
NPN21_RS28700 (154615) 154615..156816 - 2202 WP_000973519.1 Ferric aerobactin receptor VF
NPN21_RS28705 (156842) 156842..158175 - 1334 Protein_164 L-lysine N6-monooxygenase VF
NPN21_RS28710 (158172) 158172..159914 - 1743 WP_001015721.1 Aerobactin synthase VF
NPN21_RS28715 (159914) 159914..160861 - 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
NPN21_RS28720 (160862) 160862..162586 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
NPN21_RS28725 (162722) 162722..163915 + 1194 WP_000095526.1 MFS transporter -
NPN21_RS28730 (164295) 164295..164675 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
NPN21_RS28735 (165016) 165016..165429 - 414 Protein_170 phosphopyruvate hydratase -
NPN21_RS28740 (165918) 165918..166775 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
NPN21_RS28745 (166772) 166772..167629 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
NPN21_RS28750 (167626) 167626..168453 - 828 WP_000983710.1 Manganese transport system ATP-binding protein MntB VF
NPN21_RS28755 (168453) 168453..169367 - 915 WP_000949004.1 putative periplasmic iron-binding protein VF
NPN21_RS28760 (169723) 169723..170420 + 698 WP_223155668.1 IS1 family transposase IS1S Transposase
NPN21_RS28765 (170600) 170600..171113 - 514 Protein_176 DUF4113 domain-containing protein -
NPN21_RS28770 (171174) 171174..171278 - 105 Protein_177 AAA family ATPase -
NPN21_RS28775 (171280) 171280..171603 - 324 Protein_178 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance