MGE detailed information
MGE type: Conjugative plasmid MGE length: 104757 bp
Accession: NZ_CP093070 Location: 1..104757 Organism: Escherichia coli strain BR1220 Replicon: plasmid p104
Accession: NZ_CP093070 Location: 1..104757 Organism: Escherichia coli strain BR1220 Replicon: plasmid p104
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MM431_RS25195 (1) | 1..978 | + | 978 | WP_000361615.1 | RepB family plasmid replication initiator protein | - |
| MM431_RS25200 (1257) | 1257..1997 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| MM431_RS25205 (2118) | 2118..2300 | - | 183 | WP_050488504.1 | hypothetical protein | - |
| MM431_RS25210 (2367) | 2367..2657 | - | 291 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MM431_RS25215 (2644) | 2644..2912 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| MM431_RS25220 (3444) | 3444..4613 | + | 1170 | WP_032284272.1 | hypothetical protein | - |
| MM431_RS25225 (4646) | 4646..4774 | + | 129 | Protein_6 | IS481 family transposase | - |
| MM431_RS25230 (4899) | 4899..5102 | - | 204 | Protein_7 | hypothetical protein | - |
| MM431_RS25235 (5208) | 5208..5483 | - | 276 | WP_032250674.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| MM431_RS25240 (5483) | 5483..5767 | - | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| MM431_RS25245 (6681) | 6681..7538 | - | 858 | WP_032284166.1 | incFII family plasmid replication initiator RepA | - |
| MM431_RS25250 (7531) | 7531..7605 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| MM431_RS25260 (7842) | 7842..8096 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| MM431_RS25265 (8369) | 8369..8503 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (8556) | 8556..8607 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| - (8556) | 8556..8607 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| - (8556) | 8556..8607 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| - (8556) | 8556..8607 | + | 52 | NuclAT_1 | - | Antitoxin Detail |
| MM431_RS25270 (8574) | 8574..8860 | - | 287 | Protein_14 | DUF2726 domain-containing protein | - |
| MM431_RS25275 (9372) | 9372..9584 | - | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| MM431_RS25280 (9716) | 9716..10276 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| MM431_RS25285 (10331) | 10331..11077 | - | 747 | WP_000205736.1 | conjugal transfer pilus acetylase TraX | - |
| MM431_RS25290 (11097) | 11097..16367 | - | 5271 | WP_032287034.1 | Multifunctional conjugation protein TraI | Relaxase |
| MM431_RS25295 (16367) | 16367..18520 | - | 2154 | WP_241468786.1 | type IV conjugative transfer system coupling protein TraD | - |
| MM431_RS25300 (18802) | 18802..19413 | - | 612 | WP_000908442.1 | hypothetical protein | - |
| MM431_RS25305 (19485) | 19485..20216 | - | 732 | WP_001403424.1 | conjugal transfer complement resistance protein TraT | - |
| MM431_RS25310 (20265) | 20265..20750 | - | 486 | WP_077513832.1 | surface exclusion protein | - |
| MM431_RS25315 (20766) | 20766..23588 | - | 2823 | WP_001403426.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| MM431_RS25320 (23585) | 23585..24958 | - | 1374 | WP_001137364.1 | conjugal transfer pilus assembly protein TraH | - |
| MM431_RS25325 (24945) | 24945..25334 | - | 390 | WP_032284169.1 | F-type conjugal transfer protein TrbF | - |
| MM431_RS25330 (25315) | 25315..25662 | - | 348 | WP_072003757.1 | P-type conjugative transfer protein TrbJ | - |
| MM431_RS25335 (25592) | 25592..26137 | - | 546 | WP_032284162.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| MM431_RS25340 (26124) | 26124..26408 | - | 285 | WP_000623730.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| MM431_RS25345 (26535) | 26535..26873 | - | 339 | WP_001287905.1 | conjugal transfer protein TrbA | - |
| MM431_RS25350 (26889) | 26889..27632 | - | 744 | WP_001462109.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| MM431_RS25355 (27625) | 27625..27882 | - | 258 | WP_000864347.1 | conjugal transfer protein TrbE | - |
| MM431_RS25360 (27909) | 27909..29759 | - | 1851 | WP_000821866.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| MM431_RS25365 (29756) | 29756..30394 | - | 639 | WP_032165322.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| MM431_RS25370 (30403) | 30403..30708 | - | 306 | WP_000224413.1 | hypothetical protein | - |
| MM431_RS25375 (30738) | 30738..31730 | - | 993 | WP_032165320.1 | conjugal transfer pilus assembly protein TraU | - |
| MM431_RS25380 (31727) | 31727..32359 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| MM431_RS25385 (32356) | 32356..32742 | - | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| MM431_RS25390 (32739) | 32739..35366 | - | 2628 | WP_077513838.1 | type IV secretion system protein TraC | - |
| MM431_RS25395 (35526) | 35526..35747 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| MM431_RS25400 (35882) | 35882..36397 | - | 516 | WP_001403433.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MM431_RS25405 (36397) | 36397..36714 | - | 318 | WP_001057281.1 | conjugal transfer protein TrbD | - |
| MM431_RS25410 (36701) | 36701..37267 | - | 567 | WP_032269647.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| MM431_RS25415 (37257) | 37257..38708 | - | 1452 | WP_032269648.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| MM431_RS25420 (38708) | 38708..39436 | - | 729 | WP_032179724.1 | type-F conjugative transfer system secretin TraK | - |
| MM431_RS25425 (39423) | 39423..39989 | - | 567 | WP_032261454.1 | type IV conjugative transfer system protein TraE | - |
| MM431_RS25430 (40011) | 40011..40322 | - | 312 | WP_000012116.1 | type IV conjugative transfer system protein TraL | - |
| MM431_RS25435 (40337) | 40337..40702 | - | 366 | WP_001098989.1 | type IV conjugative transfer system pilin TraA | - |
| MM431_RS25440 (40735) | 40735..41136 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| MM431_RS25445 (41229) | 41229..41918 | - | 690 | WP_032173224.1 | conjugal transfer transcriptional regulator TraJ | - |
| MM431_RS25450 (42105) | 42105..42488 | - | 384 | WP_001151538.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MM431_RS25455 (42810) | 42810..43412 | + | 603 | WP_023908348.1 | hypothetical protein | VF |
| MM431_RS25460 (43707) | 43707..44528 | - | 822 | WP_024214919.1 | DUF932 domain-containing protein | - |
| MM431_RS25465 (44647) | 44647..44934 | - | 288 | WP_000107526.1 | hypothetical protein | - |
| MM431_RS25470 (45235) | 45235..45484 | + | 250 | Protein_54 | hypothetical protein | - |
| MM431_RS25475 (45785) | 45785..45910 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| MM431_RS25480 (45852) | 45852..46001 | - | 150 | Protein_56 | plasmid maintenance protein Mok | - |
| - (45987) | 45987..46211 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (45987) | 45987..46211 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (45987) | 45987..46211 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (45987) | 45987..46211 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| MM431_RS25485 (46180) | 46180..46942 | - | 763 | Protein_57 | plasmid SOS inhibition protein A | - |
| MM431_RS25490 (46939) | 46939..47373 | - | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
| MM431_RS25495 (47428) | 47428..49386 | - | 1959 | Protein_59 | ParB/RepB/Spo0J family partition protein | - |
| MM431_RS25500 (49445) | 49445..49678 | - | 234 | WP_000005970.1 | DUF905 domain-containing protein | - |
| MM431_RS25505 (49734) | 49734..50255 | - | 522 | WP_000290849.1 | single-stranded DNA-binding protein | - |
| MM431_RS25510 (50728) | 50728..50970 | - | 243 | WP_001365577.1 | hypothetical protein | - |
| MM431_RS25515 (50898) | 50898..51122 | - | 225 | WP_072003755.1 | hypothetical protein | - |
| MM431_RS25520 (51122) | 51122..51685 | - | 564 | WP_001403466.1 | class I SAM-dependent methyltransferase | - |
| MM431_RS25525 (51732) | 51732..53093 | - | 1362 | WP_000170670.1 | DUF3560 domain-containing protein | - |
| MM431_RS25530 (53145) | 53145..53375 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| MM431_RS25535 (53890) | 53890..54144 | + | 255 | Protein_67 | hypothetical protein | - |
| MM431_RS25540 (54211) | 54211..55767 | - | 1557 | Protein_68 | IS66 family transposase ISCro1 | Transposase |
| MM431_RS25545 (55787) | 55787..56134 | - | 348 | WP_000631721.1 | IS66 family transposase ISSfl3 | Transposase |
| MM431_RS25550 (56131) | 56131..56808 | - | 678 | WP_001088238.1 | IS66 family transposase ISSfl3 | Transposase |
| MM431_RS25555 (57025) | 57025..58017 | - | 993 | WP_001145106.1 | hypothetical protein | - |
| MM431_RS25560 (58066) | 58066..58221 | - | 156 | WP_000074142.1 | hypothetical protein | - |
| MM431_RS25565 (58799) | 58799..59356 | + | 558 | WP_001235702.1 | Tn3 family transposase ISEc63 | Transposase |
| MM431_RS25570 (59456) | 59456..59857 | - | 402 | WP_000085189.1 | hypothetical protein | - |
| MM431_RS25575 (60066) | 60066..61418 | - | 1353 | Protein_75 | group II intron reverse transcriptase/maturase | - |
| MM431_RS25580 (61930) | 61930..62091 | - | 162 | Protein_76 | IS3 family transposase IS2 | Transposase |
| MM431_RS25590 (62986) | 62986..64197 | - | 1212 | WP_001390768.1 | dispersin export-associated protein AatD | - |
| MM431_RS25595 (64209) | 64209..64838 | - | 630 | WP_000621743.1 | dispersin export ABC transporter ATP-binding protein AatC | - |
| MM431_RS25600 (64831) | 64831..65652 | - | 822 | WP_002431107.1 | dispersin export-associated protein AatB | - |
| MM431_RS25605 (65549) | 65549..66787 | - | 1239 | WP_162943077.1 | dispersin export ABC transporter outer membrane protein AatA | - |
| MM431_RS25610 (66784) | 66784..67914 | - | 1131 | WP_000209218.1 | dispersin export ABC transporter permease subunit AatP | - |
| MM431_RS25615 (68294) | 68294..68464 | + | 171 | Protein_82 | IS3 family transposase IS1203 | Transposase |
| MM431_RS25620 (68661) | 68661..68768 | + | 108 | Protein_83 | transposase | - |
| MM431_RS25625 (68956) | 68956..70681 | - | 1726 | Protein_84 | S6 family peptidase | - |
| MM431_RS25630 (70999) | 70999..72027 | - | 1029 | Protein_85 | IS630 family transposase | - |
| MM431_RS25635 (72210) | 72210..72410 | - | 201 | WP_000643555.1 | AggR-activated transcriptional regulator Aar | - |
| MM431_RS25640 (72516) | 72516..72831 | - | 316 | Protein_87 | hypothetical protein | - |
| MM431_RS25645 (73141) | 73141..73491 | + | 351 | WP_000721276.1 | hypothetical protein | VF |
| MM431_RS25650 (73655) | 73655..74623 | + | 969 | WP_000654804.1 | IS5 family transposase IS903B | Transposase |
| MM431_RS25655 (74665) | 74665..74861 | - | 197 | Protein_90 | IS3 family transposase | - |
| MM431_RS25660 (74857) | 74857..75182 | + | 326 | Protein_91 | IS3 family transposase | - |
| MM431_RS25665 (75398) | 75398..76195 | + | 798 | WP_086218785.1 | CFA/I fimbrial subunit D | VF |
| MM431_RS25670 (76296) | 76296..76351 | + | 56 | Protein_93 | IS1 family transposase ISEc30 | Transposase |
| MM431_RS25675 (76446) | 76446..76667 | + | 222 | Protein_94 | IS1 family transposase ISEc30 | Transposase |
| MM431_RS25680 (76943) | 76943..77946 | - | 1004 | Protein_95 | IS110 family transposase ISPlu13 | Transposase |
| MM431_RS25685 (78325) | 78325..78513 | + | 189 | Protein_96 | IS200-IS605 family transposase IS200C | Transposase |
| MM431_RS25690 (78512) | 78512..78875 | + | 364 | Protein_97 | zinc ABC transporter substrate-binding protein | - |
| MM431_RS25695 (78934) | 78934..79300 | + | 367 | Protein_98 | IS3 family transposase IS1203 | Transposase |
| MM431_RS25700 (79533) | 79533..79685 | + | 153 | WP_000565591.1 | hypothetical protein | - |
| MM431_RS25705 (79800) | 79800..80123 | - | 324 | Protein_100 | transposase | - |
| MM431_RS25710 (80188) | 80188..80727 | - | 540 | WP_175283073.1 | isopentenyl-diphosphate Delta-isomerase | - |
| MM431_RS25715 (80731) | 80731..81759 | - | 1029 | WP_001403359.1 | class 1 isoprenoid biosynthesis enzyme | - |
| MM431_RS25725 (83326) | 83326..83484 | - | 159 | Protein_104 | IS256 family transposase IS1414 | Transposase |
| MM431_RS25730 (83565) | 83565..84080 | - | 516 | WP_158662197.1 | hypothetical protein | VF |
| MM431_RS25735 (84255) | 84255..84695 | - | 441 | WP_001390764.1 | Protein AggB | VF |
| MM431_RS25740 (84709) | 84709..87258 | - | 2550 | WP_175283074.1 | F1 capsule-anchoring protein | VF |
| MM431_RS25745 (87313) | 87313..88065 | - | 753 | WP_175283077.1 | Chaperone protein caf1M | VF |
| MM431_RS25750 (88437) | 88437..89113 | + | 677 | Protein_109 | IS3 family transposase IS629 | Transposase |
| MM431_RS25755 (89172) | 89172..90074 | - | 903 | WP_241468787.1 | DUF1281 domain-containing protein | - |
| MM431_RS25760 (90349) | 90349..90597 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| MM431_RS25765 (90594) | 90594..91031 | + | 438 | WP_000109062.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| MM431_RS25770 (91031) | 91031..91936 | + | 906 | Protein_113 | translesion error-prone DNA polymerase V subunit UmuC | - |
| MM431_RS25780 (93248) | 93248..93589 | + | 342 | Protein_115 | DUF4113 domain-containing protein | - |
| MM431_RS25785 (93621) | 93621..94013 | - | 393 | WP_000340832.1 | plasmid partitioning/stability family protein | - |
| MM431_RS25790 (94018) | 94018..94989 | - | 972 | WP_001103689.1 | plasmid segregation protein ParM | - |
| MM431_RS25795 (95218) | 95218..95862 | + | 645 | WP_000633911.1 | AAA family ATPase | - |
| MM431_RS25800 (95856) | 95856..96131 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| MM431_RS25805 (96269) | 96269..97078 | - | 810 | WP_000016979.1 | site-specific integrase | - |
| MM431_RS25810 (97079) | 97079..97384 | - | 306 | WP_175283076.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| MM431_RS25815 (97386) | 97386..97604 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| MM431_RS25820 (98198) | 98198..98428 | + | 231 | WP_001261288.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| MM431_RS25825 (98452) | 98452..98853 | + | 402 | WP_001441071.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| MM431_RS25830 (99023) | 99023..101161 | - | 2139 | WP_032269946.1 | ATPase AAA | - |
| MM431_RS25835 (101385) | 101385..102942 | - | 1558 | Protein_126 | IS66 family transposase ISEc23 | Transposase |
| MM431_RS25840 (102973) | 102973..103323 | - | 351 | Protein_127 | IS66 family insertion sequence element accessory protein TnpB | - |
| MM431_RS25845 (103320) | 103320..103745 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|