MGE detailed information

MGE type: Conjugative plasmid        MGE length: 180290 bp
Accession: NZ_CP080165        Location: 1..180290         Organism: Escherichia coli strain PK8275       Replicon: plasmid pPK8275-180kb


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KZY08_RS25655 (1) 1..978 + 978 WP_063815211.1 RepB family plasmid replication initiator protein -
KZY08_RS25660 (1263) 1263..2003 - 741 WP_001066954.1 tyrosine-type recombinase/integrase -
KZY08_RS25665 (2124) 2124..2312 - 189 WP_001324033.1 hypothetical protein -
KZY08_RS25670 (2686) 2686..3588 - 903 WP_001312822.1 hypothetical protein VF
KZY08_RS25675 (3657) 3657..4766 - 1110 WP_000771475.1 SDR family oxidoreductase -
KZY08_RS25680 (5199) 5199..6152 - 954 WP_000280980.1 Protease 7 VF
KZY08_RS25685 (7449) 7449..7628 - 180 Protein_6 integrase core domain-containing protein -
KZY08_RS25690 (7767) 7767..8980 + 1214 WP_171722546.1 IS3 family transposase IS629 Transposase
KZY08_RS25695 (9128) 9128..9453 - 326 Protein_8 IS3 family transposase ISLad1 Transposase
KZY08_RS28360 (9499) 9499..9839 + 341 Protein_9 IS3 family transposase -
KZY08_RS25700 (10434) 10434..11621 + 1188 WP_000928804.1 efflux RND transporter periplasmic adaptor subunit -
KZY08_RS25705 (11618) 11618..13558 + 1941 WP_000733250.1 Macrolide export ATP-binding/permease protein MacB VF
KZY08_RS25710 (13562) 13562..14932 + 1371 WP_001312828.1 efflux transporter outer membrane subunit -
KZY08_RS25715 (15406) 15406..15600 + 195 Protein_13 IS200-IS605 family transposase IS200C Transposase
KZY08_RS25720 (15729) 15729..16670 - 942 WP_000974762.1 hypothetical protein -
KZY08_RS25725 (16905) 16905..18294 - 1390 Protein_15 ISNCY family transposase ISKpn21 Transposase
KZY08_RS25730 (18604) 18604..18753 - 150 Protein_16 IS3 family transposase IS2 Transposase
KZY08_RS25735 (18931) 18931..20124 - 1194 WP_000450494.1 GTP-binding protein -
KZY08_RS25740 (21366) 21366..22103 - 738 Protein_18 IS3 family transposase IS2 Transposase
KZY08_RS25745 (22156) 22156..23318 + 1163 WP_088846059.1 IS3 family transposase ISEc17 Transposase
KZY08_RS25750 (23335) 23335..23855 - 521 Protein_20 IS3 family transposase IS2 Transposase
KZY08_RS25755 (24480) 24480..24773 + 294 WP_000738422.1 increased serum survival lipoprotein Iss -
KZY08_RS25760 (24831) 24831..25030 - 200 Protein_22 lysis protein -
KZY08_RS25765 (25584) 25584..26608 + 1025 Protein_23 integrase core domain-containing protein -
KZY08_RS25770 (27919) 27919..29034 + 1116 WP_001318220.1 Elloramycin glycosyltransferase ElmGT VF
KZY08_RS25775 (29174) 29174..32833 + 3660 WP_001389363.1 Multidrug efflux ATP-binding/permease protein VF
KZY08_RS25780 (32937) 32937..34166 + 1230 WP_000933678.1 Enterochelin esterase VF
KZY08_RS25785 (34251) 34251..35207 + 957 WP_000271274.1 Ferri-bacillibactin esterase BesA VF
KZY08_RS25790 (35252) 35252..37429 - 2178 WP_001222185.1 Ferric enterobactin receptor VF
KZY08_RS25795 (38295) 38295..39329 - 1035 WP_001190234.1 3-deoxy-7-phosphoheptulonate synthase -
KZY08_RS28370 (39510) 39510..39811 + 302 Protein_30 hypothetical protein -
KZY08_RS25800 (39889) 39889..40182 - 294 WP_000269327.1 DUF6404 family protein -
KZY08_RS25805 (40350) 40350..40475 - 126 Protein_32 type II toxin-antitoxin system toxin YacB -
KZY08_RS25810 (40475) 40475..40743 - 269 Protein_33 type II toxin-antitoxin system antitoxin YacA -
KZY08_RS25815 (41354) 41354..42628 + 1275 WP_000489609.1 HlyD family secretion protein -
KZY08_RS25820 (42621) 42621..44717 + 2097 WP_000184924.1 microcin H47 export transporter peptidase/ATP-binding subunit MchF -
KZY08_RS25825 (44887) 44887..45198 - 312 WP_001259758.1 colicin V -
KZY08_RS25830 (45176) 45176..45412 - 237 WP_001323890.1 colicin V immunity protein -
KZY08_RS28375 (45531) 45531..45974 + 444 WP_001323891.1 dehydrogenase -
KZY08_RS28380 (45946) 45946..46350 + 405 WP_001389361.1 hypothetical protein -
KZY08_RS25840 (46352) 46352..46621 + 270 WP_000379710.1 SemiSWEET transporter -
KZY08_RS25845 (46618) 46618..47598 + 981 WP_001017346.1 NAD(P)-binding domain-containing protein -
KZY08_RS25850 (47674) 47674..48054 + 381 WP_001171523.1 IS66 family transposase ISEc8 Transposase
KZY08_RS25855 (48051) 48051..48398 + 348 WP_000612591.1 IS66 family transposase ISEc8 Transposase
KZY08_RS25860 (48448) 48448..49985 + 1538 Protein_44 IS66 family transposase ISEc8 Transposase
KZY08_RS25865 (50025) 50025..50291 + 267 Protein_45 Tn3 family transposase TnpR_TnEc1 Transposase
KZY08_RS25870 (50338) 50338..50730 - 393 Protein_46 peptide deformylase -
KZY08_RS25875 (50839) 50839..54972 - 4134 WP_001080137.1 Temperature-sensitive hemagglutinin tsh autotransporter VF
KZY08_RS25880 (55143) 55143..55334 + 192 Protein_48 IS91 family transposase -
KZY08_RS25890 (55613) 55613..55870 + 258 Protein_49 IS3 family transposase IS911 Transposase
KZY08_RS25895 (55938) 55938..57089 + 1152 WP_001442799.1 IS30 family transposase IS30D Transposase
KZY08_RS25900 (57211) 57211..57576 + 366 WP_000124098.1 hypothetical protein -
KZY08_RS25905 (57576) 57576..58691 + 1116 Protein_52 IS91 family transposase IS91 Transposase
KZY08_RS25910 (58872) 58872..59216 - 345 WP_001553768.1 hypothetical protein -
KZY08_RS25915 (60074) 60074..60892 - 819 Protein_54 Tn3 family transposase TnpA_TnAs1 Transposase
KZY08_RS25920 (60953) 60953..61655 + 703 Protein_55 IS6-like element IS26 family transposase -
KZY08_RS25925 (61807) 61807..62352 + 546 WP_001493763.1 plasmid pRiA4b ORF-3 family protein -
KZY08_RS25930 (62489) 62489..63061 + 573 WP_001493762.1 Tn3 family transposase TnpR_ISPa40 Transposase
KZY08_RS25935 (63098) 63098..64489 + 1392 WP_001493761.1 ISKra4 family transposase ISKpn19 Transposase
KZY08_RS25940 (64522) 64522..64950 + 429 Protein_59 Tn3 family transposase TnpR_ISMex22 Transposase
KZY08_RS25945 (65269) 65269..65925 - 657 WP_001516695.1 Pentapeptide repeat protein ARG
KZY08_RS25950 (66320) 66320..66936 + 617 Protein_61 transposase -
KZY08_RS25955 (67003) 67003..67707 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
KZY08_RS25960 (67653) 67653..68765 - 1113 WP_024166810.1 IS91 family transposase ISAzo26 Transposase
KZY08_RS25965 (68921) 68921..69394 + 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
KZY08_RS25970 (69641) 69641..70345 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
KZY08_RS25975 (70407) 70407..70604 - 198 WP_000844102.1 hypothetical protein -
KZY08_RS25980 (70609) 70609..71118 - 510 WP_000893479.1 restriction endonuclease -
KZY08_RS25985 (71306) 71306..71617 - 312 WP_001452736.1 hypothetical protein -
KZY08_RS25990 (71653) 71653..71967 - 315 WP_000734776.1 TrbM/KikA/MpfK family conjugal transfer protein -
KZY08_RS25995 (71930) 71930..72307 - 378 WP_000504251.1 hypothetical protein -
KZY08_RS26000 (72323) 72323..72628 - 306 WP_000960954.1 H-NS family nucleoid-associated regulatory protein -
KZY08_RS26005 (72737) 72737..73471 + 735 WP_000033783.1 Type IV secretion system protein virB1 VF
KZY08_RS26010 (73480) 73480..73761 + 282 WP_000440698.1 transcriptional repressor KorA -
KZY08_RS26015 (73771) 73771..74064 + 294 WP_000209137.1 hypothetical protein -
KZY08_RS26020 (74114) 74114..74431 + 318 WP_000496058.1 hypothetical protein VF
KZY08_RS26025 (74431) 74431..77031 + 2601 WP_001200711.1 Type IV secretion system protein virB4 VF
KZY08_RS26030 (77049) 77049..77762 + 714 WP_000749362.1 Type IV secretion system protein virB5 VF
KZY08_RS26035 (77770) 77770..77997 + 228 WP_000734973.1 IncN-type entry exclusion lipoprotein EexN -
KZY08_RS26040 (78013) 78013..79053 + 1041 WP_000886022.1 type IV secretion system protein -
KZY08_RS26045 (79136) 79136..79282 + 147 WP_001257173.1 conjugal transfer protein TraN -
KZY08_RS26050 (79272) 79272..79970 + 699 WP_000646594.1 Type IV secretion system protein virB8 VF
KZY08_RS26055 (79981) 79981..80865 + 885 WP_000735067.1 Type IV secretion system protein virB9 VF
KZY08_RS26060 (80865) 80865..82025 + 1161 WP_000101711.1 Protein virB10 VF
KZY08_RS26065 (82067) 82067..83062 + 996 WP_000128596.1 Type IV secretion system protein VirB11 VF
KZY08_RS26070 (83062) 83062..83595 + 534 WP_000731968.1 Phospholipase D VF
KZY08_RS26075 (83769) 83769..84221 - 453 WP_232380135.1 hypothetical protein -
KZY08_RS26080 (84411) 84411..85115 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
KZY08_RS26085 (85181) 85181..85453 - 273 Protein_88 Tn3 family transposase TnpR_Tn3 Transposase
KZY08_RS26090 (85617) 85617..88622 + 3006 WP_001143760.1 Tn3 family transposase TnpA_Tn3 Transposase
KZY08_RS26095 (88555) 88555..89020 - 466 Protein_90 plasmid replication initiator RepA -
KZY08_RS26100 (89013) 89013..89495 - 483 WP_001273588.1 hypothetical protein -
KZY08_RS28390 (89488) 89488..89535 - 48 WP_229471593.1 hypothetical protein -
KZY08_RS28395 (89526) 89526..89777 + 252 WP_223195197.1 replication protein RepA -
KZY08_RS26110 (89794) 89794..90051 - 258 WP_000083845.1 replication regulatory protein RepA -
KZY08_RS26115 (90335) 90335..90484 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (90528) 90528..90589 + 62 NuclAT_1 - Antitoxin Detail
- (90528) 90528..90589 + 62 NuclAT_1 - Antitoxin Detail
- (90528) 90528..90589 + 62 NuclAT_1 - Antitoxin Detail
- (90528) 90528..90589 + 62 NuclAT_1 - Antitoxin Detail
KZY08_RS26120 (90845) 90845..90919 - 75 Protein_96 endonuclease -
KZY08_RS26125 (91165) 91165..91377 - 213 WP_001299730.1 ANR family transcriptional regulator -
KZY08_RS26130 (91513) 91513..92073 - 561 WP_000139315.1 fertility inhibition protein FinO -
KZY08_RS26135 (92176) 92176..93036 - 861 WP_000704513.1 putative protein YcjY VF
KZY08_RS26140 (93095) 93095..93841 - 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
KZY08_RS26145 (93861) 93861..99131 - 5271 WP_000986963.1 Multifunctional conjugation protein TraI Relaxase
KZY08_RS26150 (99213) 99213..99440 + 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB -
KZY08_RS26155 (99440) 99440..99838 + 399 WP_000911313.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
KZY08_RS26160 (99847) 99847..102000 - 2154 WP_000009324.1 type IV conjugative transfer system coupling protein TraD -
KZY08_RS26165 (102253) 102253..102984 - 732 WP_023565183.1 conjugal transfer complement resistance protein TraT -
KZY08_RS26170 (103016) 103016..103513 - 498 WP_000605857.1 entry exclusion protein -
KZY08_RS26175 (103529) 103529..106351 - 2823 WP_001007018.1 conjugal transfer mating-pair stabilization protein TraG -
KZY08_RS26180 (106348) 106348..107721 - 1374 WP_001517790.1 conjugal transfer pilus assembly protein TraH -
KZY08_RS26185 (107721) 107721..108101 - 381 WP_001389370.1 F-type conjugal transfer protein TrbF -
KZY08_RS26190 (108088) 108088..108429 - 342 WP_001443031.1 P-type conjugative transfer protein TrbJ -
KZY08_RS26195 (108359) 108359..108904 - 546 WP_000059851.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
KZY08_RS26200 (108891) 108891..109175 - 285 WP_000624109.1 type-F conjugative transfer system pilin chaperone TraQ -
KZY08_RS26205 (109256) 109256..109570 + 315 WP_001324103.1 hypothetical protein -
KZY08_RS26210 (109572) 109572..109919 - 348 WP_001287910.1 conjugal transfer protein TrbA -
KZY08_RS26215 (109935) 109935..110678 - 744 WP_001030377.1 type-F conjugative transfer system pilin assembly protein TraF -
KZY08_RS26220 (110671) 110671..110928 - 258 WP_000864318.1 conjugal transfer protein TrbE -
KZY08_RS26225 (110955) 110955..112763 - 1809 WP_000821838.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
KZY08_RS26230 (112760) 112760..113398 - 639 WP_000777695.1 type-F conjugative transfer system pilin assembly protein TrbC -
KZY08_RS26235 (113407) 113407..114399 - 993 WP_000830183.1 conjugal transfer pilus assembly protein TraU -
KZY08_RS26240 (114396) 114396..115028 - 633 WP_001203717.1 type-F conjugative transfer system protein TraW -
KZY08_RS26245 (115025) 115025..115411 - 387 WP_000099691.1 type-F conjugative transfer system protein TrbI -
KZY08_RS26250 (115408) 115408..118035 - 2628 WP_001064245.1 type IV secretion system protein TraC -
KZY08_RS26255 (118195) 118195..118416 - 222 WP_001278689.1 conjugal transfer protein TraR -
KZY08_RS26260 (118551) 118551..119066 - 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
KZY08_RS26265 (119063) 119063..119314 - 252 WP_001038342.1 conjugal transfer protein TrbG -
KZY08_RS26270 (119326) 119326..119523 - 198 WP_024179215.1 conjugal transfer protein TrbD -
KZY08_RS26275 (119510) 119510..120100 - 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
KZY08_RS26280 (120090) 120090..121517 - 1428 WP_000146684.1 F-type conjugal transfer pilus assembly protein TraB -
KZY08_RS26285 (121517) 121517..122245 - 729 WP_001230813.1 type-F conjugative transfer system secretin TraK -
KZY08_RS26290 (122232) 122232..122798 - 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
KZY08_RS26295 (122820) 122820..123131 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
KZY08_RS26300 (123146) 123146..123511 - 366 WP_000340282.1 type IV conjugative transfer system pilin TraA -
KZY08_RS26305 (123554) 123554..123769 - 216 WP_001352842.1 conjugal transfer relaxosome protein TraY -
KZY08_RS26310 (123905) 123905..124552 - 648 WP_000332520.1 conjugal transfer transcriptional regulator TraJ -
KZY08_RS26315 (124744) 124744..125127 - 384 WP_001063020.1 conjugal transfer relaxosome DNA-binding protein TraM -
KZY08_RS26320 (125467) 125467..126069 + 603 WP_077248356.1 hypothetical protein VF
KZY08_RS26325 (126364) 126364..127185 - 822 WP_001234475.1 DUF932 domain-containing protein -
KZY08_RS26330 (127304) 127304..127591 - 288 WP_000107546.1 hypothetical protein -
KZY08_RS26335 (127892) 127892..128188 + 297 Protein_139 hypothetical protein -
KZY08_RS26340 (128489) 128489..128614 - 126 WP_096937776.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
KZY08_RS28400 (128556) 128556..128705 - 150 Protein_141 DUF5431 family protein -
- (128712) 128712..128910 - 199 NuclAT_0 - Antitoxin Detail
- (128712) 128712..128910 - 199 NuclAT_0 - Antitoxin Detail
- (128712) 128712..128910 - 199 NuclAT_0 - Antitoxin Detail
- (128712) 128712..128910 - 199 NuclAT_0 - Antitoxin Detail
KZY08_RS26345 (128879) 128879..129641 - 763 Protein_142 plasmid SOS inhibition protein A -
KZY08_RS26350 (129638) 129638..130072 - 435 WP_000845928.1 conjugation system SOS inhibitor PsiB -
KZY08_RS26355 (130127) 130127..132085 - 1959 WP_029487628.1 ParB/RepB/Spo0J family partition protein -
KZY08_RS26360 (132151) 132151..132384 - 234 WP_000005990.1 DUF905 family protein -
KZY08_RS26365 (132441) 132441..132980 - 540 WP_000290801.1 single-stranded DNA-binding protein -
KZY08_RS26370 (133298) 133298..133807 + 510 WP_071600123.1 hypothetical protein -
KZY08_RS26375 (133777) 133777..133968 - 192 WP_001027495.1 hypothetical protein -
KZY08_RS26380 (133965) 133965..134198 - 234 Protein_149 hypothetical protein -
KZY08_RS26385 (134393) 134393..135934 + 1542 WP_001298859.1 IS21 family transposase ISEc12 Transposase
KZY08_RS26390 (135949) 135949..136047 + 99 Protein_151 IS21 family transposase ISEc12 Transposase
KZY08_RS26395 (136102) 136102..137315 + 1214 WP_136952279.1 IS3 family transposase IS629 Transposase
KZY08_RS26400 (137358) 137358..138008 + 651 Protein_153 IS21 family transposase ISEc12 Transposase
KZY08_RS26405 (138093) 138093..138287 - 195 Protein_154 hypothetical protein -
KZY08_RS26410 (138334) 138334..138759 - 426 WP_001198918.1 antirestriction protein -
KZY08_RS26415 (139172) 139172..139948 - 777 WP_001005035.1 hypothetical protein -
KZY08_RS26420 (139994) 139994..140548 - 555 WP_077248347.1 DUF1380 family protein -
KZY08_RS26425 (140442) 140442..140663 - 222 WP_001104870.1 hypothetical protein -
KZY08_RS26430 (140664) 140664..141347 - 684 WP_000085939.1 DNA methylase -
KZY08_RS26435 (141424) 141424..141729 - 306 WP_010891292.1 hypothetical protein -
KZY08_RS26440 (141733) 141733..142634 - 902 Protein_161 DUF1281 domain-containing protein -
KZY08_RS26445 (143544) 143544..144515 - 972 WP_000817035.1 ParB/RepB/Spo0J family plasmid partition protein -
KZY08_RS26450 (144515) 144515..145681 - 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
KZY08_RS26455 (146269) 146269..147024 - 756 WP_000852146.1 replication initiation protein RepE -
KZY08_RS26460 (147776) 147776..148582 - 807 WP_000016982.1 site-specific integrase -
KZY08_RS26465 (148583) 148583..148888 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
KZY08_RS26470 (148890) 148890..149108 - 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA -
KZY08_RS26475 (149700) 149700..150188 + 489 WP_011254646.1 hypothetical protein -
KZY08_RS26480 (150222) 150222..151355 - 1134 WP_000545984.1 DUF3800 domain-containing protein -
KZY08_RS26485 (151522) 151522..152295 - 774 WP_000905949.1 hypothetical protein -
KZY08_RS26490 (152308) 152308..152808 - 501 WP_000528932.1 HEPN family nuclease -
KZY08_RS26495 (153073) 153073..153303 + 231 WP_001261278.1 type II toxin-antitoxin system VapB family antitoxin -
KZY08_RS26500 (153300) 153300..153716 + 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
KZY08_RS26505 (153761) 153761..157555 - 3795 WP_001144731.1 hypothetical protein -
KZY08_RS26510 (157936) 157936..158166 + 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin -
KZY08_RS26515 (158163) 158163..158579 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
KZY08_RS26520 (158654) 158654..160219 + 1566 WP_001128474.1 AAA family ATPase -
KZY08_RS26525 (160204) 160204..161226 + 1023 WP_000361402.1 helicase UvrD -
KZY08_RS26535 (162557) 162557..164758 - 2202 WP_219795292.1 Ferric aerobactin receptor VF
KZY08_RS26540 (164784) 164784..166117 - 1334 Protein_181 L-lysine N6-monooxygenase VF
KZY08_RS26545 (166114) 166114..167856 - 1743 WP_001015721.1 Aerobactin synthase VF
KZY08_RS26550 (167856) 167856..168803 - 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
KZY08_RS26555 (168804) 168804..170528 - 1725 WP_001470044.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
KZY08_RS26560 (170664) 170664..171857 + 1194 WP_000095526.1 MFS transporter -
KZY08_RS26565 (172237) 172237..172617 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
KZY08_RS26570 (172958) 172958..173371 - 414 Protein_187 phosphopyruvate hydratase -
KZY08_RS26575 (173860) 173860..174717 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
KZY08_RS26580 (174714) 174714..175571 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
KZY08_RS26585 (175568) 175568..176395 - 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
KZY08_RS26590 (176395) 176395..177309 - 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
KZY08_RS26595 (177665) 177665..178362 + 698 WP_223155668.1 IS1 family transposase IS1S Transposase
KZY08_RS26600 (178542) 178542..179055 - 514 Protein_193 DUF4113 domain-containing protein -
KZY08_RS26605 (179116) 179116..179220 - 105 Protein_194 AAA family ATPase -
KZY08_RS26610 (179222) 179222..179545 - 324 Protein_195 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance