MGE detailed information
MGE type: Mobilizable plasmid MGE length: 116491 bp
Accession: NZ_CP069982 Location: 1..116491 Organism: Escherichia coli strain FDAARGOS_1291 Replicon: plasmid unnamed2
Accession: NZ_CP069982 Location: 1..116491 Organism: Escherichia coli strain FDAARGOS_1291 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K21_RS24515 (8) | 8..253 | + | 246 | Protein_0 | antibiotic biosynthesis monooxygenase | - |
| I6K21_RS24520 (246) | 246..632 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| I6K21_RS24525 (640) | 640..1326 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| I6K21_RS24530 (1304) | 1304..1927 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| I6K21_RS24535 (2009) | 2009..3214 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| I6K21_RS24540 (3327) | 3327..3578 | - | 252 | Protein_5 | transposase | - |
| I6K21_RS24545 (3594) | 3594..4802 | - | 1209 | WP_001339175.1 | IS4 family transposase IS10R | Transposase |
| I6K21_RS24550 (4911) | 4911..5258 | - | 348 | Protein_7 | Transposon Tn10 TetC protein | VF |
| I6K21_RS24555 (5346) | 5346..5762 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| I6K21_RS24560 (5772) | 5772..6935 | - | 1164 | Protein_9 | IS4 family transposase IS10R | Transposase |
| I6K21_RS24570 (7847) | 7847..7960 | + | 114 | Protein_11 | IS6 family transposase IS15DI | Transposase |
| I6K21_RS24575 (8098) | 8098..8268 | + | 171 | Protein_12 | DsbA family protein | - |
| I6K21_RS24580 (8258) | 8258..8764 | + | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| I6K21_RS24585 (9001) | 9001..9762 | + | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| I6K21_RS24590 (10027) | 10027..11235 | + | 1209 | WP_001339175.1 | IS4 family transposase IS10R | Transposase |
| I6K21_RS24595 (11447) | 11447..13333 | + | 1887 | WP_000118029.1 | FTR1 family protein | - |
| I6K21_RS24600 (13374) | 13374..13901 | + | 528 | WP_000178050.1 | iron transporter | - |
| I6K21_RS24605 (14005) | 14005..15384 | + | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| I6K21_RS24610 (15387) | 15387..16670 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| I6K21_RS24615 (16660) | 16660..17790 | + | 1131 | WP_000729220.1 | ABC transporter permease | - |
| I6K21_RS24620 (17795) | 17795..18490 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| I6K21_RS24625 (18477) | 18477..18962 | + | 486 | WP_001267177.1 | TlpA disulfide reductase family protein | - |
| I6K21_RS24630 (18987) | 18987..19472 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| I6K21_RS24635 (19594) | 19594..20124 | + | 531 | Protein_24 | histidine-type phosphatase | - |
| I6K21_RS24640 (20182) | 20182..20886 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| I6K21_RS24645 (20911) | 20911..21632 | + | 722 | Protein_26 | IS3 family transposase IS629 | Transposase |
| I6K21_RS24650 (22305) | 22305..23813 | + | 1509 | WP_001189123.1 | group II intron reverse transcriptase/maturase | - |
| I6K21_RS24655 (23897) | 23897..24377 | + | 481 | Protein_28 | IS3 family transposase IS629 | Transposase |
| I6K21_RS24660 (24459) | 24459..24632 | + | 174 | WP_000338295.1 | Tn3 family transposase | - |
| I6K21_RS24665 (24709) | 24709..25017 | + | 309 | Protein_30 | IS4 family transposase ISEc13 | Transposase |
| I6K21_RS24670 (25076) | 25076..26386 | - | 1311 | WP_000476108.1 | ABC transporter substrate-binding protein | - |
| I6K21_RS24675 (26379) | 26379..27452 | - | 1074 | WP_000950177.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| I6K21_RS24680 (27458) | 27458..28282 | - | 825 | WP_000922702.1 | phosphodiesterase | - |
| I6K21_RS24685 (28293) | 28293..29180 | - | 888 | WP_001271561.1 | carbohydrate ABC transporter permease | - |
| I6K21_RS24690 (29170) | 29170..30048 | - | 879 | WP_000338039.1 | sugar ABC transporter permease | - |
| I6K21_RS24695 (30179) | 30179..30619 | - | 441 | Protein_36 | zinc-binding dehydrogenase | - |
| I6K21_RS24700 (31020) | 31020..31910 | + | 891 | WP_001077068.1 | dihydrodipicolinate synthase family protein | - |
| I6K21_RS24705 (31935) | 31935..32315 | + | 381 | WP_000710783.1 | Rid family detoxifying hydrolase | - |
| I6K21_RS24710 (32348) | 32348..33313 | + | 966 | WP_001022265.1 | 2-keto-3-deoxygluconate transporter | - |
| I6K21_RS24715 (33359) | 33359..34111 | - | 753 | WP_000562172.1 | IclR family transcriptional regulator | - |
| I6K21_RS24720 (34716) | 34716..35000 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| I6K21_RS24725 (35000) | 35000..35275 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| I6K21_RS24730 (35381) | 35381..35584 | + | 204 | Protein_43 | hypothetical protein | - |
| I6K21_RS24735 (35709) | 35709..35837 | - | 129 | Protein_44 | IS481 family transposase | - |
| I6K21_RS24740 (35870) | 35870..37039 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| I6K21_RS24745 (37571) | 37571..37839 | + | 269 | Protein_46 | type II toxin-antitoxin system ParD family antitoxin | - |
| I6K21_RS25720 (37826) | 37826..38115 | + | 290 | Protein_47 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| I6K21_RS24750 (38182) | 38182..38364 | + | 183 | WP_042344623.1 | hypothetical protein | - |
| I6K21_RS24755 (38485) | 38485..39225 | + | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| I6K21_RS24760 (39510) | 39510..40487 | - | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| I6K21_RS24765 (41243) | 41243..42214 | + | 972 | Protein_51 | hypothetical protein | - |
| I6K21_RS25725 (42373) | 42373..42531 | - | 159 | WP_228955855.1 | abortive infection family protein | - |
| I6K21_RS24775 (42679) | 42679..43376 | + | 698 | WP_223293341.1 | IS1 family transposase IS1R | Transposase |
| I6K21_RS24780 (43392) | 43392..43721 | + | 330 | Protein_54 | TOBE domain-containing protein | - |
| I6K21_RS24785 (43830) | 43830..44762 | - | 933 | WP_023143441.1 | homocysteine S-methyltransferase | - |
| I6K21_RS24790 (44749) | 44749..46152 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| I6K21_RS24795 (46396) | 46396..47376 | + | 981 | WP_000019407.1 | IS5 family transposase IS5D | Transposase |
| I6K21_RS24800 (47586) | 47586..47921 | + | 336 | WP_169329198.1 | type I deoxyribonuclease HsdR | - |
| I6K21_RS24805 (47871) | 47871..48284 | - | 414 | Protein_59 | integrase core domain-containing protein | - |
| I6K21_RS24810 (48289) | 48289..48567 | - | 279 | Protein_60 | pdcB | - |
| I6K21_RS24815 (48595) | 48595..48774 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| I6K21_RS24820 (48779) | 48779..49159 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| I6K21_RS24825 (49159) | 49159..49380 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| I6K21_RS24830 (49563) | 49563..50495 | + | 933 | Protein_64 | type I restriction-modification system subunit M | - |
| I6K21_RS24835 (50551) | 50551..51248 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| I6K21_RS24840 (51385) | 51385..52278 | - | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| I6K21_RS24845 (52321) | 52321..53316 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| I6K21_RS24850 (54024) | 54024..54242 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| I6K21_RS24855 (54244) | 54244..54549 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| I6K21_RS24860 (54550) | 54550..55356 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| I6K21_RS24865 (56130) | 56130..56885 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| I6K21_RS24870 (57473) | 57473..58639 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| I6K21_RS24875 (58639) | 58639..59610 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| I6K21_RS24880 (60477) | 60477..61379 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| I6K21_RS24885 (61376) | 61376..61687 | + | 312 | WP_011254640.1 | hypothetical protein | - |
| I6K21_RS24890 (61764) | 61764..62447 | + | 684 | WP_000086185.1 | DNA methylase | - |
| I6K21_RS24895 (62448) | 62448..62669 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| I6K21_RS24900 (62599) | 62599..63117 | + | 519 | WP_123325260.1 | DUF1380 family protein | - |
| I6K21_RS24905 (63168) | 63168..63944 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| I6K21_RS24910 (64361) | 64361..64786 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| I6K21_RS24915 (64833) | 64833..65255 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| I6K21_RS24920 (65252) | 65252..65443 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| I6K21_RS24925 (66478) | 66478..66708 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| I6K21_RS24930 (66760) | 66760..68121 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| I6K21_RS24935 (68169) | 68169..68732 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| I6K21_RS24940 (68758) | 68758..68988 | + | 231 | WP_021526513.1 | hypothetical protein | - |
| I6K21_RS25730 (68883) | 68883..69158 | + | 276 | WP_071780182.1 | hypothetical protein | - |
| I6K21_RS25735 (69399) | 69399..69605 | + | 207 | WP_000547975.1 | hypothetical protein | - |
| I6K21_RS24945 (69631) | 69631..70170 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| I6K21_RS24950 (70233) | 70233..70466 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| I6K21_RS24955 (70532) | 70532..72490 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| I6K21_RS24960 (72545) | 72545..72979 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| I6K21_RS24965 (72976) | 72976..73738 | + | 763 | Protein_93 | plasmid SOS inhibition protein A | - |
| I6K21_RS24970 (73707) | 73707..73895 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (73707) | 73707..73931 | + | 225 | NuclAT_0 | - | - |
| - (73707) | 73707..73931 | + | 225 | NuclAT_0 | - | - |
| - (73707) | 73707..73931 | + | 225 | NuclAT_0 | - | - |
| - (73707) | 73707..73931 | + | 225 | NuclAT_0 | - | - |
| I6K21_RS25740 (73917) | 73917..74066 | + | 150 | Protein_95 | plasmid maintenance protein Mok | - |
| I6K21_RS24975 (74008) | 74008..74133 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| I6K21_RS25745 (74353) | 74353..74583 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| I6K21_RS25750 (74581) | 74581..74754 | - | 174 | Protein_98 | hypothetical protein | - |
| I6K21_RS24980 (74824) | 74824..75030 | + | 207 | WP_000275859.1 | hypothetical protein | - |
| I6K21_RS24985 (75055) | 75055..75342 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| I6K21_RS24990 (75461) | 75461..76282 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| I6K21_RS24995 (76579) | 76579..77169 | - | 591 | WP_001376243.1 | hypothetical protein | VF |
| I6K21_RS25000 (77512) | 77512..77895 | + | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| I6K21_RS25005 (78029) | 78029..78706 | + | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| I6K21_RS25010 (78794) | 78794..79021 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| I6K21_RS25015 (79055) | 79055..79417 | + | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| I6K21_RS25020 (79422) | 79422..79733 | + | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| I6K21_RS25025 (79755) | 79755..80057 | + | 303 | Protein_108 | type IV conjugative transfer system protein TraE | - |
| I6K21_RS25030 (80118) | 80118..80815 | + | 698 | WP_223216367.1 | IS1 family transposase IS1G | Transposase |
| I6K21_RS25035 (81342) | 81342..81628 | + | 287 | Protein_110 | DUF2726 domain-containing protein | - |
| - (81595) | 81595..81655 | - | 61 | NuclAT_1 | - | - |
| - (81595) | 81595..81655 | - | 61 | NuclAT_1 | - | - |
| - (81595) | 81595..81655 | - | 61 | NuclAT_1 | - | - |
| - (81595) | 81595..81655 | - | 61 | NuclAT_1 | - | - |
| I6K21_RS25040 (81700) | 81700..81834 | + | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| I6K21_RS25045 (82131) | 82131..82385 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| I6K21_RS25055 (82622) | 82622..82696 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| I6K21_RS25060 (82689) | 82689..83546 | + | 858 | WP_000130640.1 | incFII family plasmid replication initiator RepA | - |
| I6K21_RS25065 (84486) | 84486..85139 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| I6K21_RS25070 (85232) | 85232..85489 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| I6K21_RS25075 (85422) | 85422..85823 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| I6K21_RS25080 (86108) | 86108..86248 | + | 141 | Protein_118 | DUF262 domain-containing protein | - |
| I6K21_RS25085 (86304) | 86304..87001 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| I6K21_RS25090 (87108) | 87108..87542 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| I6K21_RS25095 (87614) | 87614..87964 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| I6K21_RS25100 (87978) | 87978..88253 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| I6K21_RS25105 (88289) | 88289..88711 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| I6K21_RS25110 (88763) | 88763..90457 | + | 1695 | WP_032193845.1 | mercury(II) reductase | - |
| I6K21_RS25115 (90475) | 90475..90837 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| I6K21_RS25120 (90834) | 90834..91070 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| I6K21_RS25125 (91106) | 91106..91774 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| I6K21_RS25130 (91849) | 91849..93099 | + | 1251 | Protein_128 | transposase | - |
| I6K21_RS25135 (93164) | 93164..93868 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6K21_RS25140 (93995) | 93995..94855 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| I6K21_RS25145 (95065) | 95065..95469 | + | 405 | Protein_131 | IS91 family transposase ISPps1 | Transposase |
| I6K21_RS25150 (95576) | 95576..96412 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| I6K21_RS25155 (96412) | 96412..97215 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| I6K21_RS25160 (97276) | 97276..98091 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| I6K21_RS25755 (98421) | 98421..98507 | + | 87 | Protein_135 | Arm DNA-binding domain-containing protein | - |
| I6K21_RS25170 (98779) | 98779..99783 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| I6K21_RS25175 (99862) | 99862..101628 | - | 1767 | Protein_137 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| I6K21_RS25180 (101680) | 101680..102384 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6K21_RS25185 (102755) | 102755..103216 | + | 462 | WP_000978817.1 | thermonuclease family protein | - |
| I6K21_RS25190 (103509) | 103509..104495 | - | 987 | Protein_140 | Methyl-accepting chemotaxis protein McpQ | VF |
| I6K21_RS25195 (104557) | 104557..105261 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| I6K21_RS25200 (105383) | 105383..106288 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| I6K21_RS25205 (106285) | 106285..107523 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| I6K21_RS25210 (107523) | 107523..108107 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| I6K21_RS25215 (108600) | 108600..109364 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| I6K21_RS25220 (109427) | 109427..110092 | - | 666 | Protein_146 | IS91 family transposase ISAzo26 | Transposase |
| I6K21_RS25225 (110248) | 110248..110721 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| I6K21_RS25760 (110942) | 110942..111058 | + | 117 | Protein_148 | hypothetical protein | Relaxase |
| I6K21_RS25765 (111168) | 111168..111233 | + | 66 | Protein_149 | hypothetical protein | Relaxase |
| I6K21_RS25235 (111351) | 111351..112115 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| I6K21_RS25240 (112376) | 112376..113590 | + | 1215 | WP_004098817.1 | type II site-specific deoxyribonuclease | - |
| I6K21_RS25245 (113624) | 113624..115057 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| I6K21_RS25250 (115156) | 115156..115428 | + | 273 | Protein_153 | IS1 family transposase IS1X2 | Transposase |
| I6K21_RS25255 (115439) | 115439..115645 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| I6K21_RS25260 (115787) | 115787..116484 | + | 698 | WP_231527746.1 | IS1 family transposase IS1R | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|