NZ_CP0483381..155486

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 155486 bp
Accession: NZ_CP048338        Location: 1..155486         Organism: Escherichia coli strain 142       Replicon: plasmid p142_A-OXA181


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZS12_RS24305 () 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
GZS12_RS24310 () 1263..2003 - 741 WP_001066953.1 tyrosine-type recombinase/integrase -
GZS12_RS24315 () 2124..2306 - 183 WP_042344623.1 hypothetical protein -
GZS12_RS24320 () 2649..2956 - 308 Protein_3 type II toxin-antitoxin system ParD family antitoxin -
GZS12_RS24325 () 3449..4618 + 1170 WP_001072355.1 hypothetical protein -
GZS12_RS24330 () 4651..4779 + 129 Protein_5 IS481 family transposase -
GZS12_RS24335 () 4814..5107 - 294 WP_001105060.1 hypothetical protein -
GZS12_RS24340 () 5213..5488 - 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
GZS12_RS24345 () 5488..5772 - 285 WP_001387467.1 ribbon-helix-helix domain-containing protein Antitoxin Detail
GZS12_RS24350 () 6377..7129 + 753 WP_000562172.1 IclR family transcriptional regulator -
GZS12_RS24355 () 7175..8140 - 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
GZS12_RS24360 () 8173..8553 - 381 WP_024946717.1 Rid family detoxifying hydrolase -
GZS12_RS24365 () 8578..9468 - 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
GZS12_RS24370 () 9701..9895 - 195 WP_000796505.1 hypothetical protein -
GZS12_RS24375 () 9869..10309 + 441 Protein_14 zinc-binding dehydrogenase -
GZS12_RS24380 () 10440..11318 + 879 WP_000338039.1 sugar ABC transporter permease -
GZS12_RS24385 () 11308..12195 + 888 WP_001271561.1 carbohydrate ABC transporter permease -
GZS12_RS24390 () 12206..13030 + 825 WP_000922702.1 phosphodiesterase -
GZS12_RS24395 () 13036..14109 + 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
GZS12_RS24400 () 14102..15412 + 1311 WP_000476108.1 ABC transporter substrate-binding protein -
GZS12_RS24405 () 15471..15779 - 309 Protein_20 IS4 family transposase ISEc13 Transposase
GZS12_RS24410 () 15856..16089 - 234 Protein_21 Tn3 family transposase -
GZS12_RS24415 () 16111..17295 - 1185 Protein_22 IS3 family transposase -
GZS12_RS24420 () 17331..18032 + 702 WP_162646445.1 IS6 family transposase IS26 Transposase
GZS12_RS24425 () 18082..21669 + 3588 Protein_24 Multifunctional conjugation protein TraI Relaxase
GZS12_RS24430 () 21689..22435 + 747 WP_000205718.1 conjugal transfer pilus acetylase TraX -
GZS12_RS24435 () 22490..23050 + 561 WP_000139341.1 fertility inhibition protein FinO -
GZS12_RS24440 () 23181..23393 + 213 WP_013023861.1 hypothetical protein -
GZS12_RS24445 () 23906..24192 + 287 Protein_28 DUF2726 domain-containing protein -
- () 24159..24219 - 61 NuclAT_2 - Antitoxin Detail
- () 24159..24219 - 61 NuclAT_2 - Antitoxin Detail
- () 24159..24219 - 61 NuclAT_2 - Antitoxin Detail
- () 24159..24219 - 61 NuclAT_2 - Antitoxin Detail
GZS12_RS24450 () 24264..24398 + 135 WP_023144756.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
GZS12_RS24455 () 24695..24805 + 111 Protein_30 replication protein -
GZS12_RS24460 () 24874..25656 - 783 WP_001300609.1 IS21 family transposase IS100kyp Transposase
GZS12_RS24465 () 25653..26675 - 1023 WP_000255944.1 IS21 family transposase IS100kyp Transposase
GZS12_RS24470 () 26756..26908 + 153 WP_072258247.1 replication protein A -
GZS12_RS26115 () 27014..27148 + 135 Protein_34 protein CopA/IncA -
GZS12_RS24475 () 27145..27219 + 75 WP_031943482.1 RepA leader peptide Tap -
GZS12_RS24480 () 27212..28069 + 858 WP_000130640.1 incFII family plasmid replication initiator RepA -
GZS12_RS24485 () 29009..29662 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
GZS12_RS24490 () 29755..30012 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
GZS12_RS24495 () 29945..30346 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
GZS12_RS24500 () 30595..31010 + 416 Protein_40 IS1 family transposase -
GZS12_RS24505 () 31046..31590 - 545 Protein_41 Tn3 family transposase TnpA_Tn3 Transposase
GZS12_RS24510 () 31700..32357 - 658 Protein_42 IS6 family transposase IS26 Transposase
GZS12_RS24515 () 32423..32920 + 498 Protein_43 Tn3 family transposase ISEc63 Transposase
GZS12_RS24520 () 32956..35862 + 2907 Protein_44 Tn3 family transposase TnpA_IS3000 Transposase
GZS12_RS24525 () 36483..37280 + 798 WP_015060052.1 Beta-lactamase OXA-10 ARG
GZS12_RS24530 () 37687..37839 - 153 Protein_46 EreA family erythromycin esterase -
GZS12_RS24535 () 38215..39180 + 966 WP_064764860.1 replication initiation protein -
GZS12_RS24540 () 39144..40535 - 1392 WP_014839878.1 ISKra4 family transposase ISKpn19 Transposase
GZS12_RS24545 () 40572..41144 - 573 WP_001493762.1 Tn3 family transposase TnpR_ISPa40 Transposase
GZS12_RS24550 () 41281..41871 - 591 WP_012477564.1 plasmid pRiA4b ORF-3 family protein -
GZS12_RS24555 () 41962..42144 - 183 Protein_51 Tn3 family transposase TnpA_ISPsy30 Transposase
GZS12_RS24560 () 42306..42920 + 615 WP_014839983.1 Tn3 family transposase TnpR_ISMex22 Transposase
GZS12_RS24565 () 43239..43895 - 657 WP_001516695.1 Pentapeptide repeat protein ARG
GZS12_RS24570 () 44290..44921 + 632 Protein_54 transposase -
GZS12_RS24575 () 44975..45679 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
GZS12_RS24580 () 45747..46073 - 327 Protein_56 nucleotidyltransferase domain-containing protein -
GZS12_RS24585 () 46204..46677 - 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
GZS12_RS24590 () 46835..47515 + 681 Protein_58 IS91 family transposase ISAzo26 Transposase
GZS12_RS24595 () 47580..48284 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
GZS12_RS24600 () 48339..48593 + 255 Protein_60 SDR family oxidoreductase -
GZS12_RS24605 () 48689..49333 - 645 WP_017900990.1 Pentapeptide repeat protein ARG
GZS12_RS24610 () 49416..50390 - 975 WP_004193248.1 Psp operon transcriptional activator VF
GZS12_RS24615 () 50561..51229 + 669 WP_003020532.1 phage shock protein PspA -
GZS12_RS24620 () 51284..51508 + 225 WP_004193245.1 envelope stress response membrane protein PspB -
GZS12_RS24625 () 51508..51867 + 360 WP_004193243.1 envelope stress response membrane protein PspC -
GZS12_RS24630 () 51876..52106 + 231 WP_004193241.1 phage shock protein PspD -
GZS12_RS24635 () 52295..52465 - 171 Protein_67 LacI family transcriptional regulator -
GZS12_RS24640 () 52468..53262 - 795 Protein_68 alpha-2-macroglobulin family protein -
GZS12_RS24645 () 53457..54596 - 1140 WP_004236386.1 Beta-lactamase ARG
GZS12_RS24650 () 54707..55582 + 876 WP_004193231.1 LysR family transcriptional regulator AmpR -
GZS12_RS24655 () 55586..55951 - 366 WP_025999322.1 hydrogenase maturation nickel metallochaperone HypA -
GZS12_RS24660 () 55844..56179 + 336 WP_052238321.1 ethidium bromide resistance protein -
GZS12_RS24665 () 56173..57012 + 840 WP_000259031.1 Dihydropteroate synthase ARG
GZS12_RS24670 () 57140..57343 + 204 WP_000376616.1 hypothetical protein -
GZS12_RS24675 () 57499..58704 + 1206 WP_000184001.1 chromate efflux transporter -
GZS12_RS24680 () 58715..59020 + 306 WP_000130000.1 hypothetical protein Relaxase
GZS12_RS24685 () 59064..59129 + 66 Protein_77 EAL domain-containing protein -
GZS12_RS24690 () 59247..60011 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
GZS12_RS24695 () 60504..61088 - 585 WP_001137892.1 TetR family transcriptional regulator -
GZS12_RS24700 () 61088..62326 - 1239 WP_000004159.1 MFS transporter -
GZS12_RS24705 () 62323..63228 - 906 WP_000219391.1 hypothetical protein ARG
GZS12_RS24710 () 63350..64054 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
GZS12_RS24715 () 64113..64655 + 543 WP_024946707.1 Tn3 family transposase TnpR_TnAs3 Transposase
GZS12_RS24720 () 64658..67624 + 2967 WP_001138064.1 Tn3 family transposase TnpA_TnAs3 Transposase
GZS12_RS24725 () 67691..68068 + 378 WP_000656305.1 GNAT family N-acetyltransferase -
GZS12_RS24730 () 68269..68928 - 660 WP_000412211.1 Chloramphenicol acetyltransferase ARG
GZS12_RS24735 () 69207..69904 + 698 Protein_87 IS1 family transposase IS1S Transposase
GZS12_RS24740 () 69901..70164 + 264 WP_049802299.1 antibiotic biosynthesis monooxygenase -
GZS12_RS24745 () 70157..70543 + 387 WP_000460651.1 hypothetical protein -
GZS12_RS24750 () 70551..71237 + 687 WP_001284954.1 winged helix-turn-helix domain-containing protein -
GZS12_RS24755 () 71215..71838 - 624 WP_000088605.1 Tetracycline repressor protein class B from transposon Tn10 VF
GZS12_RS24760 () 71920..73125 + 1206 WP_001089068.1 Tetracycline resistance protein, class B ARG
GZS12_RS24765 () 73238..73831 - 594 WP_000428546.1 tetracyline resistance-associated transcriptional repressor TetC -
GZS12_RS24770 () 73990..74687 - 698 Protein_94 IS1 family transposase IS1X2 Transposase
GZS12_RS26120 () 74887..75000 + 114 Protein_95 IS6 family transposase -
GZS12_RS24775 () 75150..75308 + 159 WP_000449408.1 DsbA family protein -
GZS12_RS24780 () 75298..75804 + 507 WP_000949452.1 protein disulfide oxidoreductase -
GZS12_RS24785 () 75987..76802 + 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
GZS12_RS24790 () 77149..79035 + 1887 WP_000118029.1 FTR1 family iron permease -
GZS12_RS24795 () 79076..79603 + 528 WP_000178050.1 iron transporter -
GZS12_RS24800 () 79707..81086 + 1380 WP_000119836.1 DUF2318 domain-containing protein -
GZS12_RS24805 () 81089..82372 + 1284 WP_000964653.1 ABC transporter permease -
GZS12_RS24810 () 82362..83492 + 1131 WP_000729220.1 ABC transporter permease -
GZS12_RS24815 () 83497..84192 + 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
GZS12_RS24820 () 84179..84664 + 486 WP_001267177.1 TlpA family protein disulfide reductase -
GZS12_RS24825 () 84689..85174 + 486 WP_000874189.1 hypothetical protein -
GZS12_RS24830 () 85296..85826 + 531 Protein_107 histidine-type phosphatase -
GZS12_RS24835 () 85884..86588 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
GZS12_RS24840 () 86656..88341 - 1686 Protein_109 Multifunctional conjugation protein TraI Relaxase
GZS12_RS24845 () 88341..90512 - 2172 WP_032153767.1 type IV conjugative transfer system coupling protein TraD -
GZS12_RS24850 () 90509..91288 - 780 WP_000199914.1 hypothetical protein -
GZS12_RS24855 () 91491..92222 - 732 WP_000850429.1 complement resistance protein TraT -
GZS12_RS24860 () 92254..92751 - 498 WP_000605862.1 entry exclusion protein -
GZS12_RS24865 () 92770..95589 - 2820 WP_001007062.1 conjugal transfer mating pair stabilization protein TraG -
GZS12_RS24870 () 95586..96959 - 1374 WP_000944328.1 conjugal transfer protein TraH -
GZS12_RS24875 () 96946..97371 - 426 WP_001348758.1 F-type conjugal transfer protein TrbF -
GZS12_RS24880 () 97319..97666 - 348 WP_071571857.1 P-type conjugative transfer protein TrbJ -
GZS12_RS24885 () 97596..98141 - 546 WP_000059829.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
GZS12_RS24890 () 98128..98412 - 285 WP_001617873.1 type-F conjugative transfer system pilin chaperone TraQ -
GZS12_RS24895 () 98539..98859 - 321 WP_001348757.1 conjugal transfer protein TrbA -
GZS12_RS24900 () 98907..99604 - 698 Protein_121 IS1 family transposase IS1G Transposase
GZS12_RS24905 () 99719..100321 + 603 WP_000243712.1 hypothetical protein VF
GZS12_RS24910 () 100618..101439 - 822 WP_162646450.1 DUF945 domain-containing protein -
GZS12_RS24915 () 101558..101845 - 288 WP_000107535.1 hypothetical protein -
GZS12_RS26125 () 101870..102076 - 207 WP_000275859.1 hypothetical protein -
GZS12_RS24925 () 102767..102871 - 105 WP_112047136.1 Hok/Gef family protein Toxin Detail
GZS12_RS24930 () 102865..102981 - 117 WP_162646446.1 DUF5431 family protein -
- () 102967..103094 - 128 NuclAT_0 - Antitoxin Detail
- () 102967..103094 - 128 NuclAT_0 - Antitoxin Detail
- () 102967..103094 - 128 NuclAT_0 - Antitoxin Detail
- () 102967..103094 - 128 NuclAT_0 - Antitoxin Detail
GZS12_RS24935 () 103121..104487 - 1367 Protein_128 IS3 family transposase -
- () 104533..104635 - 103 NuclAT_1 - -
- () 104533..104635 - 103 NuclAT_1 - -
- () 104533..104635 - 103 NuclAT_1 - -
- () 104533..104635 - 103 NuclAT_1 - -
GZS12_RS24940 () 104647..105366 - 720 WP_001276232.1 plasmid SOS inhibition protein A -
GZS12_RS24945 () 105363..105797 - 435 WP_000845940.1 conjugation system SOS inhibitor PsiB -
GZS12_RS24950 () 105852..107810 - 1959 WP_000117179.1 ParB/RepB/Spo0J family partition protein -
GZS12_RS24955 () 107876..108109 - 234 WP_000005990.1 DUF905 family protein -
GZS12_RS24960 () 108172..108711 - 540 WP_000290841.1 single-stranded DNA-binding protein -
GZS12_RS24970 () 109354..109578 - 225 WP_016238251.1 hypothetical protein -
GZS12_RS24975 () 109604..110167 - 564 WP_162646447.1 class I SAM-dependent methyltransferase -
GZS12_RS24980 () 110215..111576 - 1362 WP_000170714.1 DUF3560 domain-containing protein -
GZS12_RS24985 () 111628..111858 - 231 WP_000218642.1 hypothetical protein -
GZS12_RS24990 () 112893..113084 - 192 WP_001027516.1 hypothetical protein -
GZS12_RS24995 () 113081..113503 - 423 WP_000271753.1 DUF1380 family protein -
GZS12_RS25000 () 113550..113852 - 303 WP_001671341.1 antirestriction protein -
GZS12_RS25010 () 114392..115168 - 777 WP_001753849.1 hypothetical protein -
GZS12_RS25015 () 115219..115653 - 435 WP_000274437.1 DUF1380 family protein -
GZS12_RS25020 () 115667..115888 - 222 WP_001104873.1 hypothetical protein -
GZS12_RS25025 () 115889..116572 - 684 WP_000086185.1 DNA methylase -
GZS12_RS25030 () 116649..116953 - 305 Protein_145 hypothetical protein -
GZS12_RS25035 () 116957..117859 - 903 WP_001348615.1 DUF1281 domain-containing protein -
GZS12_RS25040 () 118726..119697 - 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
GZS12_RS25045 () 119697..120863 - 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
GZS12_RS25050 () 121451..122206 - 756 WP_024946706.1 replication initiation protein RepE -
GZS12_RS25055 () 122980..123786 - 807 WP_000016982.1 site-specific integrase -
GZS12_RS25060 () 123787..124092 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
GZS12_RS25065 () 124094..124312 - 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
GZS12_RS25070 () 124879..125391 + 513 WP_000151784.1 hypothetical protein -
GZS12_RS25075 () 125425..126558 - 1134 WP_001542067.1 DUF3800 domain-containing protein -
GZS12_RS25080 () 126725..127498 - 774 WP_000905949.1 hypothetical protein -
GZS12_RS25085 () 127511..128011 - 501 WP_000528931.1 hypothetical protein -
GZS12_RS25090 () 128276..128506 + 231 WP_001261278.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
GZS12_RS25095 () 128503..128919 + 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
GZS12_RS25100 () 128964..132758 - 3795 WP_001144732.1 hypothetical protein -
GZS12_RS25105 () 133139..133369 + 231 WP_001261286.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
GZS12_RS25110 () 133366..133782 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
GZS12_RS25115 () 133857..135415 + 1559 Protein_162 AAA family ATPase -
GZS12_RS25120 () 135400..136422 + 1023 WP_000361402.1 helicase UvrD -
GZS12_RS25125 () 136676..137373 - 698 Protein_164 IS1 family transposase IS1S Transposase
GZS12_RS25130 () 137729..138643 + 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
GZS12_RS25135 () 138643..139470 + 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
GZS12_RS25140 () 139467..140324 + 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
GZS12_RS25145 () 140321..141178 + 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
GZS12_RS25150 () 141412..141669 - 258 Protein_169 Tn3 family transposase -
GZS12_RS25155 () 141667..142080 + 414 Protein_170 phosphopyruvate hydratase -
GZS12_RS25160 () 142421..142801 + 381 WP_001318207.1 fluoride efflux transporter CrcB -
GZS12_RS25165 () 143181..144374 - 1194 WP_000095526.1 MFS transporter -
GZS12_RS25170 () 144510..146234 + 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
GZS12_RS25175 () 146235..147183 + 949 Protein_174 N(6)-hydroxylysine O-acetyltransferase VF
GZS12_RS25180 () 147183..148925 + 1743 WP_162646448.1 Aerobactin synthase VF
GZS12_RS25185 () 148922..150199 + 1278 WP_162646449.1 L-lysine N6-monooxygenase VF
GZS12_RS25190 () 150281..152482 + 2202 WP_000973519.1 Ferric aerobactin receptor VF
GZS12_RS25195 () 152862..153558 + 697 Protein_178 IS1 family transposase IS1A Transposase
GZS12_RS25200 () 153738..154251 - 514 Protein_179 DUF4113 domain-containing protein -
GZS12_RS26130 () 154312..154416 - 105 Protein_180 AAA family ATPase -
GZS12_RS25205 () 154418..154741 - 324 Protein_181 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance