MGE detailed information

MGE type: Conjugative plasmid        MGE length: 195702 bp
Accession: NZ_CP041299        Location: 1..195702         Organism: Escherichia coli O1:H42 strain CLSC36       Replicon: plasmid pCys-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FK541_RS00010 () 158..523 + 366 WP_000340276.1 type IV conjugative transfer system pilin TraA -
FK541_RS00015 () 538..849 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
FK541_RS00020 () 871..1436 + 566 Protein_3 type IV conjugative transfer system protein TraE -
FK541_RS00025 () 1447..2151 + 705 WP_072095570.1 type-F conjugative transfer system secretin TraK -
FK541_RS00030 () 2151..3578 + 1428 WP_084818640.1 conjugal transfer protein TraB -
FK541_RS00035 () 3568..4158 + 591 WP_000002787.1 conjugal transfer protein TraP -
FK541_RS00040 () 4112..4342 + 231 WP_001352845.1 conjugal transfer protein TrbD -
FK541_RS00045 () 4354..4605 + 252 WP_001038351.1 conjugal transfer protein TrbG -
FK541_RS00050 () 4602..5117 + 516 WP_084818641.1 type IV conjugative transfer system lipoprotein TraV -
FK541_RS00055 () 5252..5473 + 222 WP_001278690.1 conjugal transfer protein TraR -
FK541_RS00060 () 5633..8260 + 2628 WP_001064245.1 type IV secretion system protein TraC -
FK541_RS00065 () 8257..8643 + 387 WP_000099688.1 type-F conjugative transfer system protein TrbI -
FK541_RS00070 () 8640..9272 + 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
FK541_RS00075 () 9269..10261 + 993 WP_000830183.1 conjugal transfer pilus assembly protein TraU -
FK541_RS00080 () 10270..10908 + 639 WP_000777703.1 type-F conjugative transfer system pilin assembly protein TrbC -
FK541_RS00085 () 10905..12713 + 1809 Protein_16 type-F conjugative transfer system mating-pair stabilization protein TraN -
FK541_RS00090 () 12740..12997 + 258 WP_000864318.1 conjugal transfer protein TrbE -
FK541_RS00095 () 12990..13732 + 743 Protein_18 type-F conjugative transfer system pilin assembly protein TraF -
FK541_RS00100 () 13748..14095 + 348 WP_001287907.1 conjugal transfer protein TrbA -
FK541_RS00105 () 14097..14372 - 276 WP_001513501.1 hypothetical protein -
FK541_RS00110 () 14453..14737 + 285 WP_000624108.1 type-F conjugative transfer system pilin chaperone TraQ -
FK541_RS00115 () 14724..15269 + 546 WP_000059833.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
FK541_RS00120 () 15199..15540 + 342 WP_001442101.1 P-type conjugative transfer protein TrbJ -
FK541_RS00135 () 15906..17279 + 1374 WP_000944319.1 conjugal transfer protein TraH -
FK541_RS00140 () 17276..20100 + 2825 Protein_25 conjugal transfer mating pair stabilization protein TraG -
FK541_RS00145 () 20097..20606 + 510 WP_000628105.1 conjugal transfer entry exclusion protein TraS -
FK541_RS00150 () 20620..21351 + 732 WP_000850416.1 complement resistance protein TraT -
FK541_RS00160 () 21604..23757 + 2154 WP_000009379.1 type IV conjugative transfer system coupling protein TraD -
FK541_RS00165 () 23766..24164 - 399 WP_000911333.1 tRNA(fMet)-specific endonuclease VapC Toxin Detail
FK541_RS00170 () 24164..24391 - 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
FK541_RS00180 () 24871..29744 + 4874 Protein_31 Multifunctional conjugation protein TraI Relaxase
FK541_RS00185 () 29764..30510 + 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
FK541_RS00190 () 30569..31429 + 861 WP_000704513.1 putative protein YcjY VF
FK541_RS00195 () 31532..32092 + 561 WP_000139315.1 fertility inhibition protein FinO -
FK541_RS00200 () 32228..32440 + 213 WP_001299730.1 ANR family transcriptional regulator -
FK541_RS25655 () 32686..32760 + 75 Protein_36 endonuclease -
- () 33016..33077 - 62 NuclAT_1 - -
- () 33016..33077 - 62 NuclAT_1 - -
- () 33016..33077 - 62 NuclAT_1 - -
- () 33016..33077 - 62 NuclAT_1 - -
FK541_RS00210 () 33064..33270 + 207 WP_001351576.1 type I toxin-antitoxin system Hok family toxin -
FK541_RS00215 () 33554..33811 + 258 WP_000083845.1 replication regulatory protein RepA -
FK541_RS00225 () 34043..34117 + 75 WP_001442103.1 RepA leader peptide Tap -
FK541_RS00230 () 34110..34592 + 483 WP_001273588.1 hypothetical protein -
FK541_RS00235 () 34585..35442 + 858 WP_019842754.1 incFII family plasmid replication initiator RepA -
FK541_RS00240 () 35739..37316 - 1578 WP_001323889.1 Aerotaxis receptor VF
FK541_RS00245 () 37626..38186 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
FK541_RS00250 () 38190..41156 + 2967 WP_138031477.1 Tn3 family transposase TnpA_TnAs1 Transposase
FK541_RS00255 () 42051..42302 + 252 WP_001132900.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
FK541_RS00260 () 42299..42586 + 288 WP_000222760.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
FK541_RS00270 () 43026..43373 - 348 Protein_47 IS1-like element IS1A family transposase -
FK541_RS00275 () 43462..44484 + 1023 WP_000255956.1 IS21 family transposase IS100kyp Transposase
FK541_RS00280 () 44481..45263 + 783 WP_001442137.1 IS21 family transposase IS100kyp Transposase
FK541_RS00285 () 45318..45682 - 365 Protein_50 IS1 family transposase -
FK541_RS00290 () 45782..47003 + 1222 Protein_51 ISL3 family transposase ISEc38 Transposase
FK541_RS00295 () 47839..48801 - 963 WP_000661609.1 carbamate kinase family protein -
FK541_RS00300 () 48828..50378 - 1551 WP_141927140.1 xanthine permease -
FK541_RS00305 () 50491..51909 - 1419 WP_000084168.1 DUF1116 domain-containing protein -
FK541_RS00310 () 51909..53456 - 1548 WP_000027750.1 acyl-CoA synthetase FdrA -
FK541_RS00315 () 53416..54264 - 849 WP_000531854.1 DUF2877 domain-containing protein -
FK541_RS00320 () 54350..54955 - 606 WP_000066154.1 ankyrin repeat domain-containing protein -
FK541_RS00325 () 55343..56272 + 930 WP_001084376.1 putative HTH-type transcriptional regulator YahB VF
FK541_RS00330 () 56946..57266 - 321 WP_001334006.1 IS3 family transposase ISEc31 Transposase
FK541_RS00335 () 57931..58628 + 698 Protein_60 IS1 family transposase IS1S Transposase
FK541_RS00340 () 58644..58922 + 279 Protein_61 serine acetyltransferase -
FK541_RS00345 () 59025..59690 + 666 WP_000536047.1 hypothetical protein -
FK541_RS00350 () 59748..60038 + 291 WP_000633743.1 hypothetical protein -
FK541_RS25660 () 60716..61192 - 477 Protein_64 Multidrug resistance ABC transporter ATP-binding/permease protein BmrA VF
FK541_RS25765 () 61187..62220 - 1034 Protein_65 Multidrug resistance ABC transporter ATP-binding/permease protein BmrA VF
FK541_RS00360 () 62427..62816 - 390 WP_000595317.1 cytochrome B562 -
FK541_RS00365 () 63250..64140 - 891 WP_000470711.1 putative HTH-type transcriptional regulator YahB VF
FK541_RS00370 () 64218..65441 - 1224 WP_024188138.1 cytosine permease -
FK541_RS00375 () 65464..65853 - 390 WP_001696803.1 hypothetical protein -
FK541_RS00380 () 65870..66826 - 957 WP_001696801.1 carbamate kinase -
FK541_RS00385 () 66819..68243 - 1425 WP_001093931.1 DUF1116 domain-containing protein -
FK541_RS00390 () 68240..69799 - 1560 WP_000865634.1 acyl-CoA synthetase FdrA -
FK541_RS00395 () 69894..70754 - 861 WP_001442105.1 DUF2877 domain-containing protein -
FK541_RS00400 () 70760..71428 - 669 WP_000155780.1 cysteine hydrolase -
FK541_RS00405 () 71887..72318 - 432 Protein_75 relaxase NikB -
FK541_RS25670 () 72375..73023 + 649 Protein_76 IS3 family transposase IS1203 Transposase
FK541_RS00425 () 73067..73897 - 831 Protein_77 IS66 family transposase ISEc43 Transposase
FK541_RS00430 () 73894..74061 + 168 Protein_78 type II toxin-antitoxin system RelE/ParE family toxin -
FK541_RS25675 () 74107..74286 + 180 Protein_79 3'-5' exonuclease -
FK541_RS00440 () 74447..74718 - 272 Protein_80 hypothetical protein -
FK541_RS00445 () 74814..75047 + 234 WP_000451769.1 HNH endonuclease -
FK541_RS00450 () 75048..75305 + 258 WP_000412701.1 bacteriocin immunity protein -
FK541_RS00455 () 75383..76569 - 1187 Protein_83 MFS transporter -
FK541_RS00460 () 76626..77387 - 762 WP_000020503.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
FK541_RS00465 () 77387..78424 - 1038 WP_000110581.1 Hemin transport system permease protein HmuU VF
FK541_RS00470 () 78424..79422 - 999 WP_000756335.1 ABC transporter substrate-binding protein -
FK541_RS00475 () 79572..79730 - 159 Protein_87 integrase core domain-containing protein -
FK541_RS00480 () 79777..80367 - 591 WP_000086538.1 Tn3 family transposase TnpR_ISSba14 Transposase
FK541_RS00490 () 80945..81955 - 1011 WP_000487120.1 IS110 family transposase IS1663 Transposase
FK541_RS00495 () 82157..82422 - 266 Protein_90 IS91 family transposase ISEc37 Transposase
FK541_RS00500 () 82422..82787 - 366 WP_000124098.1 hypothetical protein -
FK541_RS00510 () 82909..84060 - 1152 WP_029402714.1 IS30 family transposase IS30D Transposase
FK541_RS00520 () 84128..84385 - 258 Protein_93 IS3 family transposase IS911 Transposase
FK541_RS00525 () 84481..84696 + 216 Protein_94 helix-turn-helix domain-containing protein -
FK541_RS00530 () 84664..84858 - 195 Protein_95 IS91 family transposase -
FK541_RS00535 () 85026..89157 + 4132 Protein_96 Hemoglobin-binding protease hbp autotransporter VF
FK541_RS00540 () 89266..89717 + 452 Protein_97 peptide deformylase -
FK541_RS00545 () 89704..89970 - 267 Protein_98 Tn3 family transposase TnpR_TnEc1 Transposase
FK541_RS00550 () 90010..91284 - 1275 Protein_99 IS66 family transposase ISEc8 Transposase
FK541_RS00555 () 91334..91681 - 348 WP_000612591.1 IS66 family transposase ISEc8 Transposase
FK541_RS00560 () 91678..92058 - 381 WP_024210439.1 IS66 family transposase ISEc8 Transposase
FK541_RS00565 () 92134..93113 - 980 Protein_102 NAD(P)/FAD-dependent oxidoreductase -
FK541_RS00575 () 93110..93379 - 270 WP_000379710.1 SemiSWEET transporter -
FK541_RS00580 () 93381..94158 - 778 Protein_104 gfo/Idh/MocA family oxidoreductase -
FK541_RS00585 () 94319..94555 + 237 WP_001323890.1 colicin V immunity protein -
FK541_RS00590 () 94533..94844 + 312 WP_001259758.1 colicin V -
FK541_RS00595 () 95014..97128 - 2115 WP_001183603.1 peptidase domain-containing ABC transporter -
FK541_RS00600 () 97103..98377 - 1275 WP_000489608.1 HlyD family secretion protein -
FK541_RS00605 () 99059..99256 + 198 WP_001324224.1 toxin-antitoxin system protein Antitoxin Detail
FK541_RS00610 () 99253..99435 + 183 WP_000969988.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
FK541_RS00615 () 99534..99842 + 309 WP_000377483.1 hypothetical protein -
FK541_RS00625 () 100402..101436 + 1035 WP_001190233.1 3-deoxy-7-phosphoheptulonate synthase -
FK541_RS00645 () 102281..104457 + 2177 Protein_113 Ferrienterobactin receptor VF
FK541_RS00650 () 104502..105458 - 957 WP_000271277.1 Ferri-bacillibactin esterase BesA VF
FK541_RS00655 () 105543..106771 - 1229 Protein_115 Enterochelin esterase VF
FK541_RS00660 () 106875..110534 - 3660 WP_001442133.1 Multidrug efflux ATP-binding/permease protein VF
FK541_RS00665 () 110674..111789 - 1116 WP_001318220.1 Elloramycin glycosyltransferase ElmGT VF
FK541_RS00675 () 113025..114124 - 1100 Protein_118 IS481 family transposase ISKpn28 Transposase
FK541_RS00685 () 114735..114876 + 142 Protein_119 lysis system i-spanin subunit Rz -
FK541_RS00690 () 114934..115227 - 294 WP_000738422.1 increased serum survival lipoprotein Iss -
FK541_RS00695 () 115934..117162 + 1229 WP_164994192.1 IS3 family transposase IS2 Transposase
FK541_RS00700 () 117617..118810 + 1194 WP_000450493.1 GTP-binding protein -
FK541_RS00705 () 118988..119137 + 150 Protein_123 IS3 family transposase IS2 Transposase
FK541_RS00710 () 119445..120842 + 1398 WP_001610305.1 ISNCY family transposase ISKpn21 Transposase
FK541_RS00715 () 121074..121343 + 270 WP_001610304.1 hypothetical protein -
FK541_RS00720 () 121343..121810 + 468 WP_001610303.1 hypothetical protein -
FK541_RS00725 () 121853..122224 + 372 WP_001610302.1 hypothetical protein -
FK541_RS00730 () 122460..123805 + 1346 Protein_128 ISNCY family transposase ISLad2 Transposase
FK541_RS00735 () 124211..124315 - 105 Protein_129 IS3 family transposase IS1351 Transposase
FK541_RS00740 () 124566..126830 - 2265 WP_001610298.1 UvrD-helicase domain-containing protein -
FK541_RS00745 () 126832..127608 - 777 WP_001610297.1 hypothetical protein -
FK541_RS00750 () 128360..129673 - 1314 Protein_132 IS4 family transposase -
FK541_RS00755 () 130004..131374 - 1371 WP_001696614.1 efflux transporter outer membrane subunit -
FK541_RS00760 () 131378..133318 - 1941 WP_001610286.1 Macrolide export ATP-binding/permease protein MacB VF
FK541_RS00765 () 133315..134502 - 1188 WP_001696612.1 efflux RND transporter periplasmic adaptor subunit -
FK541_RS00770 () 136217..136633 + 417 WP_001595315.1 IS3 family transposase IS1351 Transposase
FK541_RS00785 () 137906..138859 + 954 WP_000280980.1 Protease 7 VF
FK541_RS00795 () 139291..140400 + 1110 WP_001696610.1 SDR family oxidoreductase -
FK541_RS00800 () 140469..141371 + 903 WP_001312822.1 hypothetical protein VF
FK541_RS00805 () 141746..141934 + 189 WP_001312821.1 hypothetical protein -
FK541_RS00810 () 142055..142795 + 741 WP_001066954.1 tyrosine-type recombinase/integrase -
FK541_RS00815 () 143080..144057 - 978 WP_000361611.1 RepB family plasmid replication initiator protein -
FK541_RS00825 () 144803..145126 + 324 Protein_143 IS21 family transposase IS21 Transposase
FK541_RS25680 () 145128..145232 + 105 Protein_144 AAA family ATPase -
FK541_RS00835 () 145293..145806 + 514 Protein_145 DUF4113 domain-containing protein -
FK541_RS00840 () 145986..146683 - 698 Protein_146 IS1 family transposase IS1S Transposase
FK541_RS00850 () 147039..147953 + 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
FK541_RS00855 () 147953..148780 + 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
FK541_RS00860 () 148777..149634 + 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
FK541_RS00865 () 149631..150488 + 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
FK541_RS00870 () 150722..150978 - 257 Protein_151 Tn3 family transposase -
FK541_RS00875 () 150976..151389 + 414 Protein_152 phosphopyruvate hydratase -
FK541_RS00885 () 151730..152110 + 381 WP_001318207.1 fluoride efflux transporter CrcB -
FK541_RS00890 () 152489..153682 - 1194 WP_000095528.1 MFS transporter -
FK541_RS00895 () 153818..155542 + 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
FK541_RS00900 () 155543..156489 + 947 Protein_156 N(6)-hydroxylysine O-acetyltransferase VF
FK541_RS00905 () 156489..158231 + 1743 WP_001015721.1 Aerobactin synthase VF
FK541_RS00910 () 158228..159505 + 1278 WP_000750130.1 L-lysine N6-monooxygenase VF
FK541_RS00915 () 159587..161788 + 2202 WP_000973519.1 Ferric aerobactin receptor VF
FK541_RS00920 () 162168..162865 + 698 Protein_160 IS1 family transposase IS1S Transposase
FK541_RS00925 () 163118..164140 - 1023 WP_000361402.1 helicase UvrD -
FK541_RS00930 () 164125..165690 - 1566 WP_001128474.1 AAA family ATPase -
FK541_RS00935 () 165765..166181 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
FK541_RS00940 () 166178..166408 - 231 WP_001261286.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
FK541_RS00945 () 166789..170583 + 3795 WP_171003983.1 pcar -
FK541_RS00950 () 170628..171044 - 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
FK541_RS00955 () 171041..171271 - 231 WP_001261278.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin Detail
FK541_RS00960 () 171536..172036 + 501 WP_000528932.1 hypothetical protein -
FK541_RS00965 () 172049..172822 + 774 WP_000905949.1 hypothetical protein -
FK541_RS00970 () 172989..174122 + 1134 WP_000545987.1 DUF3800 domain-containing protein -
FK541_RS00975 () 174156..174668 - 513 WP_000151784.1 hypothetical protein -
FK541_RS00985 () 175234..175452 + 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
FK541_RS00990 () 175454..175759 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
FK541_RS00995 () 175760..176565 + 806 Protein_174 IS91 family transposase ISShvi3 Transposase
FK541_RS01000 () 177245..177976 - 732 WP_000504262.1 replication initiation protein -
FK541_RS01005 () 178597..179802 + 1206 WP_001442122.1 Plasmid partition protein A VF
FK541_RS01010 () 179799..180770 + 972 WP_001233385.1 ParB/RepB/Spo0J family partition protein -
FK541_RS01020 () 180907..182052 - 1146 Protein_178 translesion error-prone DNA polymerase V subunit UmuC -
FK541_RS01025 () 182115..183113 + 999 WP_084818645.1 IS91 family transposase ISMno24 Transposase
FK541_RS01030 () 183110..184020 + 911 Protein_180 hypothetical protein -
FK541_RS01035 () 184097..185318 + 1222 Protein_181 tyrosine-type recombinase/integrase -
FK541_RS01040 () 185375..186072 - 698 Protein_182 IS1 family transposase IS1S Transposase
FK541_RS01050 () 186724..187221 + 498 WP_050427786.1 single-stranded DNA-binding protein -
FK541_RS01055 () 187284..187517 + 234 WP_001209608.1 DUF905 domain-containing protein -
FK541_RS01060 () 187576..189534 + 1959 Protein_185 ParB/RepB/Spo0J family partition protein -
FK541_RS01065 () 189589..190023 + 435 WP_000845935.1 conjugation system SOS inhibitor PsiB -
FK541_RS01070 () 190020..190739 + 720 WP_001276275.1 plasmid SOS inhibition protein A -
- () 190750..190961 + 212 NuclAT_0 - -
- () 190750..190961 + 212 NuclAT_0 - -
- () 190750..190961 + 212 NuclAT_0 - -
- () 190750..190961 + 212 NuclAT_0 - -
FK541_RS01080 () 191014..191175 + 162 WP_001332444.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
FK541_RS01085 () 191413..192025 - 613 Protein_189 hypothetical protein -
FK541_RS01090 () 192204..193025 + 822 WP_001234485.1 DUF945 domain-containing protein -
FK541_RS01095 () 193321..193911 - 591 WP_000252676.1 hypothetical protein VF
FK541_RS01105 () 194246..194629 + 384 WP_000124981.1 relaxosome protein TraM -
FK541_RS01110 () 194819..195505 + 687 WP_000332490.1 PAS domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance