MGE detailed information
MGE type: Conjugative plasmid MGE length: 134794 bp
Accession: NZ_CP027866 Location: 1..134794 Organism: Klebsiella pneumoniae subsp. pneumoniae strain CRKP18622 Replicon: plasmid pCRKP18622-KPC
Accession: NZ_CP027866 Location: 1..134794 Organism: Klebsiella pneumoniae subsp. pneumoniae strain CRKP18622 Replicon: plasmid pCRKP18622-KPC
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C7K64_RS27700 (316) | 316..813 | - | 498 | Protein_1 | IS1 family transposase | - |
| C7K64_RS27705 (858) | 858..1082 | - | 225 | WP_001243832.1 | IS1-like element transposase | - |
| C7K64_RS27710 (1185) | 1185..1417 | - | 233 | Protein_3 | hypothetical protein | - |
| C7K64_RS27715 (1856) | 1856..2134 | - | 279 | WP_264460072.1 | Major pilu subunit operon regulatory protein PapB | VF |
| C7K64_RS27720 (2671) | 2671..3095 | - | 425 | Protein_5 | IS3 family transposase IS2 | Transposase |
| C7K64_RS27725 (3377) | 3377..5347 | + | 1971 | WP_001496335.1 | Hemin receptor | VF |
| C7K64_RS27730 (5354) | 5354..6145 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| C7K64_RS27735 (6208) | 6208..6816 | - | 609 | Protein_8 | IS66 family transposase ISEc22 | Transposase |
| C7K64_RS27740 (6884) | 6884..7666 | - | 783 | WP_001317493.1 | IS21 family transposase IS100kyp | Transposase |
| C7K64_RS27745 (7663) | 7663..8598 | - | 936 | Protein_10 | IS21 family transposase IS100kyp | Transposase |
| C7K64_RS27750 (8648) | 8648..9352 | - | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| C7K64_RS27755 (9699) | 9699..10712 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| C7K64_RS27760 (10892) | 10892..11446 | + | 555 | WP_032488579.1 | aminoglycoside N-acetyltransferase AAC(6')-Ib3 | - |
| C7K64_RS27765 (11713) | 11713..12972 | + | 1260 | Protein_14 | Inner membrane transport protein YdhC | ARG |
| C7K64_RS27770 (13164) | 13164..13511 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| C7K64_RS27775 (13505) | 13505..13714 | + | 210 | Protein_16 | dihydropteroate synthase | - |
| C7K64_RS27780 (13903) | 13903..14934 | - | 1032 | WP_014342102.1 | Methyl-accepting chemotaxis protein McpQ | VF |
| C7K64_RS27785 (15135) | 15135..16397 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| C7K64_RS27790 (16647) | 16647..17522 | + | 876 | WP_001617865.1 | Beta-lactamase CTX-M-97 | ARG |
| C7K64_RS27795 (17557) | 17557..18525 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| C7K64_RS27800 (18582) | 18582..19679 | + | 1098 | Protein_21 | TonB-dependent receptor | - |
| C7K64_RS27805 (19747) | 19747..20223 | - | 477 | Protein_22 | PAS domain-containing protein | - |
| C7K64_RS27810 (20276) | 20276..20980 | - | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| C7K64_RS27815 (21017) | 21017..21206 | - | 190 | Protein_24 | Tn3 family transposase | - |
| C7K64_RS27820 (21536) | 21536..22396 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| C7K64_RS27825 (22579) | 22579..22977 | - | 399 | Protein_26 | Tn3 family transposase TnpR_Tn3 | Transposase |
| C7K64_RS27830 (23040) | 23040..23744 | + | 705 | WP_001067845.1 | IS6 family transposase IS26 | Transposase |
| C7K64_RS27835 (23831) | 23831..24178 | - | 348 | WP_000142451.1 | DUF6404 family protein | - |
| C7K64_RS27840 (24307) | 24307..24642 | + | 336 | WP_001080730.1 | colicin 1A immunity protein | - |
| C7K64_RS27845 (24664) | 24664..25032 | - | 369 | Protein_30 | colicin-like pore-forming protein | - |
| C7K64_RS27850 (25097) | 25097..25794 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| C7K64_RS27855 (25844) | 25844..26119 | - | 276 | WP_000421257.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| C7K64_RS27860 (26119) | 26119..26403 | - | 285 | WP_001178089.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| C7K64_RS27865 (26914) | 26914..27618 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C7K64_RS27870 (28024) | 28024..28641 | + | 618 | Protein_35 | replication protein | - |
| C7K64_RS27875 (29175) | 29175..29453 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| C7K64_RS27880 (29564) | 29564..29989 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| C7K64_RS27885 (30117) | 30117..30272 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| C7K64_RS27890 (30318) | 30318..30614 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| C7K64_RS27895 (30718) | 30718..31599 | + | 882 | Protein_40 | IS1182 family transposase ISKpn6 | Transposase |
| C7K64_RS27900 (31849) | 31849..32730 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| C7K64_RS27905 (33006) | 33006..33986 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| C7K64_RS27910 (34109) | 34109..34570 | - | 462 | Protein_43 | Tn3 family transposase TnpR_Tn3 | Transposase |
| C7K64_RS27915 (34622) | 34622..35326 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| C7K64_RS27920 (35795) | 35795..36358 | - | 564 | WP_155082050.1 | hypothetical protein | - |
| C7K64_RS27925 (36480) | 36480..37022 | - | 543 | WP_077273850.1 | restriction endonuclease | - |
| C7K64_RS27930 (37004) | 37004..37984 | - | 981 | WP_000019445.1 | IS5 family transposase ISKpn26 | Transposase |
| C7K64_RS27935 (38315) | 38315..38716 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| C7K64_RS27940 (38649) | 38649..38906 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| C7K64_RS27945 (38999) | 38999..39652 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| C7K64_RS27950 (40591) | 40591..41448 | - | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| C7K64_RS27955 (41441) | 41441..41515 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| C7K64_RS27960 (41760) | 41760..42008 | - | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| C7K64_RS27965 (42293) | 42293..42442 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (42487) | 42487..42546 | + | 60 | NuclAT_1 | - | - |
| - (42487) | 42487..42546 | + | 60 | NuclAT_1 | - | - |
| - (42487) | 42487..42546 | + | 60 | NuclAT_1 | - | - |
| - (42487) | 42487..42546 | + | 60 | NuclAT_1 | - | - |
| C7K64_RS27970 (42689) | 42689..43162 | - | 474 | WP_016240489.1 | hypothetical protein | - |
| C7K64_RS27975 (43317) | 43317..43907 | - | 591 | WP_033807967.1 | DUF2726 domain-containing protein | - |
| C7K64_RS27980 (43945) | 43945..44154 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| C7K64_RS27985 (44200) | 44200..44661 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| C7K64_RS27990 (44906) | 44906..45118 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| C7K64_RS27995 (45247) | 45247..45807 | - | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| C7K64_RS28000 (45910) | 45910..46770 | - | 861 | WP_000704523.1 | putative protein YcjY | VF |
| C7K64_RS28005 (46829) | 46829..47575 | - | 747 | WP_059338983.1 | conjugal transfer pilus acetylase TraX | - |
| C7K64_RS28010 (47595) | 47595..52865 | - | 5271 | WP_172691999.1 | Multifunctional conjugation protein TraI | Relaxase |
| C7K64_RS28015 (52865) | 52865..55144 | - | 2280 | WP_087760849.1 | Coupling protein TraD | VF |
| C7K64_RS28020 (55195) | 55195..55932 | - | 738 | WP_000199905.1 | hypothetical protein | - |
| C7K64_RS28025 (56135) | 56135..56866 | - | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| C7K64_RS28030 (56915) | 56915..57400 | - | 486 | WP_000605870.1 | hypothetical protein | - |
| C7K64_RS28035 (57416) | 57416..60238 | - | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| C7K64_RS28040 (60235) | 60235..61617 | - | 1383 | WP_001309243.1 | conjugal transfer pilus assembly protein TraH | - |
| C7K64_RS28045 (61595) | 61595..61987 | - | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| C7K64_RS28050 (61968) | 61968..62315 | - | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| C7K64_RS28055 (62245) | 62245..62790 | - | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| C7K64_RS28060 (62777) | 62777..63061 | - | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| C7K64_RS28065 (63180) | 63180..63524 | - | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| C7K64_RS28070 (63538) | 63538..64287 | - | 750 | WP_001336806.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| C7K64_RS28075 (64274) | 64274..64531 | - | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| C7K64_RS28080 (64558) | 64558..66408 | - | 1851 | WP_000821856.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| C7K64_RS28085 (66405) | 66405..67043 | - | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| C7K64_RS28090 (67052) | 67052..67357 | - | 306 | WP_000224416.1 | hypothetical protein | - |
| C7K64_RS28095 (67387) | 67387..68379 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| C7K64_RS28100 (68376) | 68376..69008 | - | 633 | WP_001203728.1 | type-F conjugative transfer system protein TraW | - |
| C7K64_RS28105 (69005) | 69005..69391 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| C7K64_RS28110 (69388) | 69388..72018 | - | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| C7K64_RS28115 (72144) | 72144..72491 | - | 348 | WP_000836682.1 | hypothetical protein | - |
| C7K64_RS28120 (72519) | 72519..72737 | - | 219 | WP_000556745.1 | hypothetical protein | - |
| C7K64_RS28125 (72817) | 72817..73293 | - | 477 | WP_000549587.1 | hypothetical protein | - |
| C7K64_RS28130 (73286) | 73286..73507 | - | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| C7K64_RS28135 (73642) | 73642..74157 | - | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| C7K64_RS28140 (74154) | 74154..74474 | - | 321 | WP_001057307.1 | conjugal transfer protein TrbD | - |
| C7K64_RS28145 (74461) | 74461..75027 | - | 567 | WP_000896599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| C7K64_RS28150 (75017) | 75017..76468 | - | 1452 | WP_000146675.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| C7K64_RS28155 (76468) | 76468..77196 | - | 729 | WP_001230772.1 | type-F conjugative transfer system secretin TraK | - |
| C7K64_RS28160 (77183) | 77183..77749 | - | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| C7K64_RS28165 (77771) | 77771..78082 | - | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| C7K64_RS28170 (78097) | 78097..78456 | - | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
| C7K64_RS28175 (78489) | 78489..78716 | - | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| C7K64_RS28180 (78853) | 78853..79524 | - | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| C7K64_RS28185 (79718) | 79718..80101 | - | 384 | WP_001354030.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| C7K64_RS28190 (80436) | 80436..81026 | + | 591 | WP_000252683.1 | hypothetical protein | VF |
| C7K64_RS28195 (81323) | 81323..82144 | - | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| C7K64_RS28200 (82255) | 82255..82551 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| C7K64_RS28205 (82851) | 82851..83147 | + | 297 | Protein_102 | hypothetical protein | - |
| C7K64_RS28210 (83466) | 83466..83591 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| C7K64_RS28215 (83533) | 83533..83682 | - | 150 | Protein_104 | plasmid maintenance protein Mok | - |
| - (83668) | 83668..83892 | - | 225 | NuclAT_0 | - | - |
| - (83668) | 83668..83892 | - | 225 | NuclAT_0 | - | - |
| - (83668) | 83668..83892 | - | 225 | NuclAT_0 | - | - |
| - (83668) | 83668..83892 | - | 225 | NuclAT_0 | - | - |
| C7K64_RS28220 (83904) | 83904..84623 | - | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| C7K64_RS28225 (84620) | 84620..85054 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| C7K64_RS28230 (85123) | 85123..87146 | - | 2024 | Protein_107 | ParB/RepB/Spo0J family partition protein | - |
| C7K64_RS28235 (87207) | 87207..87440 | - | 234 | WP_000006003.1 | DUF905 family protein | - |
| C7K64_RS28240 (87498) | 87498..88025 | - | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| C7K64_RS28245 (88327) | 88327..88776 | + | 450 | Protein_110 | hypothetical protein | - |
| C7K64_RS28250 (88862) | 88862..89425 | - | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| C7K64_RS28255 (89472) | 89472..90833 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| C7K64_RS28260 (90885) | 90885..91115 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| C7K64_RS28265 (91632) | 91632..91786 | + | 155 | Protein_114 | hypothetical protein | - |
| C7K64_RS28270 (92515) | 92515..94182 | + | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| C7K64_RS28275 (94496) | 94496..94687 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| C7K64_RS28280 (94684) | 94684..95106 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| C7K64_RS28285 (95153) | 95153..95578 | - | 426 | WP_089079046.1 | antirestriction protein | - |
| C7K64_RS28290 (95992) | 95992..96762 | - | 771 | WP_001006225.1 | hypothetical protein | - |
| C7K64_RS28295 (96807) | 96807..97293 | - | 487 | Protein_120 | DUF1380 domain-containing protein | - |
| C7K64_RS28300 (97253) | 97253..97474 | - | 222 | WP_001104887.1 | hypothetical protein | - |
| C7K64_RS28305 (97475) | 97475..98158 | - | 684 | WP_000086160.1 | DNA methylase | - |
| C7K64_RS28310 (98234) | 98234..98539 | - | 306 | WP_032155763.1 | hypothetical protein | - |
| C7K64_RS28315 (98543) | 98543..99445 | - | 903 | WP_001302618.1 | DUF1281 domain-containing protein | - |
| C7K64_RS28320 (99863) | 99863..100111 | + | 249 | WP_000618110.1 | DinI-like family protein | - |
| C7K64_RS28325 (100108) | 100108..100545 | + | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| C7K64_RS28330 (100545) | 100545..101816 | + | 1272 | WP_000457496.1 | Y-family DNA polymerase | - |
| C7K64_RS28335 (101821) | 101821..102213 | - | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| C7K64_RS28340 (102218) | 102218..103189 | - | 972 | WP_001103697.1 | plasmid segregation protein ParM | - |
| C7K64_RS28345 (103418) | 103418..104062 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| C7K64_RS28350 (104056) | 104056..104331 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| C7K64_RS28355 (104523) | 104523..104949 | - | 427 | Protein_132 | site-specific integrase | - |
| C7K64_RS28360 (105129) | 105129..105719 | + | 591 | Protein_133 | colicin-B | - |
| C7K64_RS28370 (106488) | 106488..106682 | - | 195 | Protein_135 | colicin M immunity protein | - |
| C7K64_RS28375 (106854) | 106854..107663 | - | 810 | WP_000016963.1 | site-specific integrase | - |
| C7K64_RS28380 (107664) | 107664..107969 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| C7K64_RS28385 (107971) | 107971..108189 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| C7K64_RS28390 (108750) | 108750..108980 | + | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| C7K64_RS28395 (108977) | 108977..109393 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| C7K64_RS28400 (109468) | 109468..111033 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| C7K64_RS28405 (111018) | 111018..112040 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| C7K64_RS28410 (112294) | 112294..112980 | - | 687 | Protein_143 | IS1 family transposase IS1S | Transposase |
| C7K64_RS28415 (113506) | 113506..115707 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| C7K64_RS28420 (115733) | 115733..117066 | - | 1334 | Protein_145 | L-lysine N6-monooxygenase | VF |
| C7K64_RS28425 (117063) | 117063..118805 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| C7K64_RS28430 (118805) | 118805..119752 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| C7K64_RS28435 (119753) | 119753..121477 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| C7K64_RS28440 (121613) | 121613..122806 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| C7K64_RS28445 (123186) | 123186..123566 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| C7K64_RS28450 (123907) | 123907..124320 | - | 414 | Protein_151 | phosphopyruvate hydratase | - |
| C7K64_RS28455 (124318) | 124318..124575 | + | 258 | Protein_152 | transposase | - |
| C7K64_RS28460 (124809) | 124809..125666 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| C7K64_RS28465 (125663) | 125663..126520 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| C7K64_RS28470 (126517) | 126517..127344 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| C7K64_RS28475 (127344) | 127344..128258 | - | 915 | WP_000949005.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| C7K64_RS28480 (128614) | 128614..129300 | + | 687 | Protein_157 | IS1 family transposase | - |
| C7K64_RS28485 (129480) | 129480..129993 | - | 514 | Protein_158 | DUF4113 domain-containing protein | - |
| C7K64_RS28490 (130054) | 130054..130158 | - | 105 | Protein_159 | AAA family ATPase | - |
| C7K64_RS28495 (130160) | 130160..130483 | - | 324 | Protein_160 | IS21 family transposase IS21 | Transposase |
| C7K64_RS28500 (131229) | 131229..132206 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| C7K64_RS28505 (132449) | 132449..133189 | - | 741 | WP_001066952.1 | tyrosine-type recombinase/integrase | - |
| C7K64_RS28510 (133310) | 133310..133498 | - | 189 | WP_001309252.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|