MGE detailed information

MGE type: Conjugative plasmid        MGE length: 147186 bp
Accession: NZ_AP022162        Location: 1..147186         Organism: Escherichia coli strain WP5-S18-ESBL-08       Replicon: plasmid pWP5-S18-ESBL-08_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- () 53..113 - 61 NuclAT_2 - Antitoxin Detail
- () 53..113 - 61 NuclAT_2 - Antitoxin Detail
- () 53..113 - 61 NuclAT_2 - Antitoxin Detail
- () 53..113 - 61 NuclAT_2 - Antitoxin Detail
H7R36_RS24850 () 158..292 + 135 WP_023144756.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
H7R36_RS24855 () 589..699 + 111 Protein_2 replication protein -
H7R36_RS24860 () 768..1547 - 780 WP_001323403.1 IS21 family transposase IS100kyp Transposase
H7R36_RS24865 () 1547..2569 - 1023 WP_000255944.1 IS21 family transposase IS100kyp Transposase
H7R36_RS24870 () 2650..2802 + 153 WP_072258247.1 replication protein A -
H7R36_RS26745 () 2908..3042 + 135 Protein_6 protein CopA/IncA -
H7R36_RS24875 () 3039..3113 + 75 WP_031943482.1 RepA leader peptide Tap -
H7R36_RS24880 () 3106..3963 + 858 WP_000130640.1 incFII family plasmid replication initiator RepA -
H7R36_RS24885 () 4665..4805 + 141 WP_001333237.1 hypothetical protein -
H7R36_RS24890 () 4903..5556 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
H7R36_RS24895 () 5649..5906 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
H7R36_RS24900 () 5839..6240 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
H7R36_RS24905 () 6489..6904 + 416 Protein_13 IS1 family transposase -
H7R36_RS24910 () 6940..7485 - 546 Protein_14 Tn3 family transposase TnpA_Tn3 Transposase
H7R36_RS24915 () 7551..8255 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H7R36_RS24920 () 8320..9000 - 681 Protein_16 IS91 family transposase ISAzo26 Transposase
H7R36_RS24925 () 9158..9631 + 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
H7R36_RS24930 () 9762..10550 + 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
H7R36_RS24935 () 10756..11103 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
H7R36_RS24940 () 11097..11936 + 840 WP_000259031.1 Dihydropteroate synthase ARG
H7R36_RS24945 () 12064..12267 + 204 WP_000376616.1 hypothetical protein -
H7R36_RS24950 () 12423..13628 + 1206 WP_000184001.1 chromate efflux transporter -
H7R36_RS24955 () 13639..13944 + 306 WP_000130000.1 hypothetical protein Relaxase
H7R36_RS24960 () 13988..14053 + 66 Protein_24 EAL domain-containing protein -
H7R36_RS24965 () 14171..14935 + 765 WP_001389365.1 IS6-like element IS6100 family transposase -
H7R36_RS24970 () 15428..16012 - 585 WP_001137892.1 TetR family transcriptional regulator -
H7R36_RS24975 () 16012..17250 - 1239 WP_000004159.1 MFS transporter -
H7R36_RS24980 () 17247..18152 - 906 WP_000219391.1 hypothetical protein ARG
H7R36_RS24985 () 18274..18978 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H7R36_RS24990 () 19043..21286 - 2244 Protein_30 Tn3 family transposase TnpA_Tn3 Transposase
H7R36_RS24995 () 21300..21632 + 333 WP_001393253.1 WbuC family cupin fold metalloprotein -
H7R36_RS25000 () 21679..22554 - 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
H7R36_RS25005 () 22810..24072 - 1263 WP_032153699.1 IS1380 family transposase ISEcp1 Transposase
H7R36_RS25010 () 24278..24472 - 195 Protein_34 Tn3 family transposase TnpA_Tn3 Transposase
H7R36_RS25015 () 24636..25193 + 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
H7R36_RS25020 () 25376..26236 + 861 WP_000027057.1 Beta-lactamase TEM ARG
H7R36_RS25025 () 26462..26641 + 180 WP_000214483.1 hypothetical protein -
H7R36_RS25030 () 26696..26977 + 282 Protein_38 CcgAII protein -
H7R36_RS25035 () 27085..27921 - 837 WP_045893453.1 hypothetical protein ARG
H7R36_RS25040 () 27921..28724 - 804 WP_024261901.1 Aminoglycoside 3'-phosphotransferase ARG
H7R36_RS25050 () 30107..30811 + 705 WP_001067834.1 IS6 family transposase IS26 Transposase
H7R36_RS25055 () 30876..31085 + 210 WP_071992733.1 hypothetical protein -
H7R36_RS25060 () 31078..31464 + 387 WP_000460651.1 hypothetical protein -
H7R36_RS25065 () 31472..32158 + 687 WP_001284954.1 winged helix-turn-helix domain-containing protein -
H7R36_RS25070 () 32136..32759 - 624 WP_000088605.1 Tetracycline repressor protein class B from transposon Tn10 VF
H7R36_RS25075 () 32841..34046 + 1206 WP_001089068.1 Tetracycline resistance protein, class B ARG
H7R36_RS25080 () 34159..34752 - 594 WP_000428546.1 tetracyline resistance-associated transcriptional repressor TetC -
H7R36_RS25085 () 34911..35608 - 698 Protein_49 IS1 family transposase IS1X2 Transposase
H7R36_RS25090 () 36071..36229 + 159 WP_000449408.1 DsbA family protein -
H7R36_RS25095 () 36219..36725 + 507 WP_000949452.1 protein disulfide oxidoreductase -
H7R36_RS25100 () 36908..37723 + 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
H7R36_RS25105 () 38070..39956 + 1887 WP_000118029.1 FTR1 family iron permease -
H7R36_RS25110 () 39997..40524 + 528 WP_000178050.1 iron transporter -
H7R36_RS25115 () 40628..42007 + 1380 WP_000119836.1 DUF2318 domain-containing protein -
H7R36_RS25120 () 42010..43293 + 1284 WP_000964653.1 ABC transporter permease -
H7R36_RS25125 () 43283..44413 + 1131 WP_000729220.1 ABC transporter permease -
H7R36_RS25130 () 44418..45113 + 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
H7R36_RS25135 () 45100..45585 + 486 WP_001267177.1 TlpA family protein disulfide reductase -
H7R36_RS25140 () 45610..46095 + 486 WP_000874189.1 hypothetical protein -
H7R36_RS25145 () 46217..46747 + 531 Protein_61 histidine-type phosphatase -
H7R36_RS25150 () 46805..47509 - 705 WP_001067834.1 IS3 family transposase IS1203 Transposase
H7R36_RS25155 () 47534..48730 + 1197 Protein_63 IS3 family transposase -
H7R36_RS25160 () 48752..48985 + 234 Protein_64 Tn3 family transposase ISPsy39 Transposase
H7R36_RS25165 () 49062..49370 + 309 Protein_65 IS4 family transposase ISEc13 Transposase
H7R36_RS25170 () 49429..50739 - 1311 WP_000476108.1 ABC transporter substrate-binding protein -
H7R36_RS25175 () 50732..51805 - 1074 WP_000950177.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC VF
H7R36_RS25180 () 51811..52635 - 825 WP_000922702.1 phosphodiesterase -
H7R36_RS25185 () 52646..53533 - 888 WP_001271561.1 carbohydrate ABC transporter permease -
H7R36_RS25190 () 53523..54401 - 879 WP_000338039.1 sugar ABC transporter permease -
H7R36_RS25195 () 54532..54972 - 441 Protein_71 zinc-binding dehydrogenase -
H7R36_RS25200 () 54946..55140 + 195 WP_000796505.1 hypothetical protein -
H7R36_RS25205 () 55373..56263 + 891 WP_001077068.1 dihydrodipicolinate synthase family protein -
H7R36_RS25210 () 56288..56668 + 381 WP_000710783.1 Rid family detoxifying hydrolase -
H7R36_RS25215 () 56701..57666 + 966 WP_001022265.1 2-keto-3-deoxygluconate transporter -
H7R36_RS25220 () 57712..58464 - 753 WP_000562172.1 IclR family transcriptional regulator -
H7R36_RS25225 () 59069..59353 + 285 WP_001387467.1 ribbon-helix-helix domain-containing protein -
H7R36_RS25230 () 59353..59628 + 276 WP_000421272.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
H7R36_RS25235 () 59734..60027 + 294 WP_001105060.1 hypothetical protein -
H7R36_RS25240 () 60062..60190 - 129 Protein_80 IS481 family transposase -
H7R36_RS25245 () 60223..61392 - 1170 WP_001072355.1 hypothetical protein -
H7R36_RS25250 () 61885..62192 + 308 Protein_82 type II toxin-antitoxin system ParD family antitoxin -
H7R36_RS25255 () 62535..62717 + 183 WP_042344623.1 hypothetical protein -
H7R36_RS25260 () 62838..63578 + 741 WP_001066953.1 tyrosine-type recombinase/integrase -
H7R36_RS25265 () 63863..64840 - 978 WP_000361611.1 RepB family plasmid replication initiator protein -
H7R36_RS25270 () 65586..65909 + 324 Protein_86 IS21 family transposase IS21 Transposase
H7R36_RS25275 () 65911..66015 + 105 Protein_87 AAA family ATPase -
H7R36_RS25280 () 66076..66589 + 514 Protein_88 DUF4113 domain-containing protein -
H7R36_RS25285 () 66769..67466 - 698 Protein_89 IS1 family transposase IS1S Transposase
H7R36_RS25290 () 67846..70047 - 2202 WP_000973519.1 Ferric aerobactin receptor VF
H7R36_RS25295 () 70129..71406 - 1278 WP_000750130.1 L-lysine N6-monooxygenase VF
H7R36_RS25300 () 71403..73145 - 1743 WP_001015721.1 Aerobactin synthase VF
H7R36_RS25305 () 73145..74092 - 948 WP_000011908.1 N(6)-hydroxylysine O-acetyltransferase VF
H7R36_RS25310 () 74093..75817 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
H7R36_RS25315 () 75953..77146 + 1194 WP_000095526.1 MFS transporter -
H7R36_RS25320 () 77526..77906 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
H7R36_RS25325 () 78247..78660 - 414 Protein_97 phosphopyruvate hydratase -
H7R36_RS25330 () 78658..78915 + 258 Protein_98 Tn3 family transposase -
H7R36_RS25335 () 79149..80006 - 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
H7R36_RS25340 () 80003..80860 - 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
H7R36_RS25345 () 80857..81684 - 828 WP_000983710.1 Iron(3+)-hydroxamate import ATP-binding protein FhuC VF
H7R36_RS25350 () 81684..82598 - 915 WP_000949004.1 Putative metal ABC transporter substrate-binding protein Hpf VF
H7R36_RS25355 () 82954..83651 + 698 Protein_103 IS1 family transposase IS1S Transposase
H7R36_RS25360 () 83905..84927 - 1023 WP_000361402.1 helicase UvrD -
H7R36_RS25365 () 84912..86477 - 1566 WP_001128474.1 AAA family ATPase -
H7R36_RS25370 () 86552..86968 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
H7R36_RS25375 () 86965..87195 - 231 WP_001261286.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
H7R36_RS25380 () 87576..91370 + 3795 WP_001144732.1 hypothetical protein -
H7R36_RS25385 () 91415..91831 - 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
H7R36_RS25390 () 91828..92058 - 231 WP_001261278.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
H7R36_RS25395 () 92323..92823 + 501 WP_000528931.1 hypothetical protein -
H7R36_RS25400 () 92836..93609 + 774 WP_000905949.1 hypothetical protein -
H7R36_RS25405 () 93776..94909 + 1134 WP_001542067.1 DUF3800 domain-containing protein -
H7R36_RS25410 () 94943..95455 - 513 WP_000151784.1 hypothetical protein -
H7R36_RS25415 () 96022..96240 + 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA -
H7R36_RS25420 () 96242..96547 + 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
H7R36_RS25425 () 96548..97354 + 807 WP_000016982.1 site-specific integrase -
H7R36_RS25430 () 98128..98883 + 756 WP_024946706.1 replication initiation protein RepE -
H7R36_RS25435 () 99471..100637 + 1167 WP_000772446.1 Sporulation initiation inhibitor protein Soj VF
H7R36_RS25440 () 100637..101608 + 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
H7R36_RS25445 () 102475..103377 + 903 WP_001348615.1 DUF1281 domain-containing protein -
H7R36_RS25450 () 103381..103685 + 305 Protein_122 hypothetical protein -
H7R36_RS25455 () 103762..104445 + 684 WP_000086185.1 DNA methylase -
H7R36_RS25460 () 104446..104667 + 222 WP_001104873.1 hypothetical protein -
H7R36_RS25465 () 104681..105115 + 435 WP_000274437.1 DUF1380 family protein -
H7R36_RS25470 () 105166..105942 + 777 WP_001753849.1 hypothetical protein -
H7R36_RS25475 () 106482..106784 + 303 WP_001671341.1 antirestriction protein -
H7R36_RS25480 () 106831..107253 + 423 WP_000271753.1 DUF1380 family protein -
H7R36_RS25485 () 107250..107441 + 192 WP_001027516.1 hypothetical protein -
H7R36_RS25490 () 107655..107810 + 156 WP_001744062.1 hypothetical protein -
H7R36_RS25495 () 108476..108706 + 231 WP_000218642.1 hypothetical protein -
H7R36_RS25500 () 108758..110119 + 1362 WP_000170714.1 DUF3560 domain-containing protein -
H7R36_RS25505 () 110167..110730 + 564 WP_001348621.1 class I SAM-dependent methyltransferase -
H7R36_RS25510 () 110756..110974 + 219 WP_001496291.1 hypothetical protein -
H7R36_RS26750 () 110881..111144 + 264 WP_071781663.1 hypothetical protein -
H7R36_RS25520 () 111617..112156 + 540 WP_000290841.1 single-stranded DNA-binding protein -
H7R36_RS25525 () 112219..112452 + 234 WP_000005990.1 DUF905 family protein -
H7R36_RS25530 () 112518..114476 + 1959 WP_000117179.1 ParB/RepB/Spo0J family partition protein -
H7R36_RS25535 () 114531..114965 + 435 WP_000845940.1 conjugation system SOS inhibitor PsiB -
H7R36_RS25540 () 114962..115681 + 720 WP_001276232.1 plasmid SOS inhibition protein A -
- () 115693..115795 + 103 NuclAT_1 - -
- () 115693..115795 + 103 NuclAT_1 - -
- () 115693..115795 + 103 NuclAT_1 - -
- () 115693..115795 + 103 NuclAT_1 - -
H7R36_RS25545 () 115841..117210 + 1370 WP_085947770.1 IS3 family transposase IS150 Transposase
- () 117237..117364 + 128 NuclAT_0 - -
- () 117237..117364 + 128 NuclAT_0 - -
- () 117237..117364 + 128 NuclAT_0 - -
- () 117237..117364 + 128 NuclAT_0 - -
- () 117297..117362 + 66 - - Antitoxin Detail
H7R36_RS25550 () 117408..117566 + 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
H7R36_RS25555 () 117861..118016 + 156 WP_001380190.1 hypothetical protein -
H7R36_RS25560 () 118341..119096 - 756 WP_001282653.1 IS21 family transposase ISSso4 Transposase
H7R36_RS25565 () 119113..120648 - 1536 WP_000447015.1 IS21 family transposase ISSso4 Transposase
H7R36_RS25570 () 120902..121108 + 207 WP_000275859.1 hypothetical protein -
H7R36_RS25575 () 121133..121420 + 288 WP_000107535.1 hypothetical protein -
H7R36_RS25580 () 121539..122360 + 822 WP_001234469.1 DUF945 domain-containing protein -
H7R36_RS25585 () 122657..123259 - 603 WP_000243712.1 hypothetical protein VF
H7R36_RS25590 () 123590..123973 + 384 WP_001151566.1 relaxosome protein TraM -
H7R36_RS25595 () 124107..124784 + 678 WP_001348626.1 PAS domain-containing protein -
H7R36_RS25600 () 124872..125099 + 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
H7R36_RS25605 () 125133..125495 + 363 WP_000338606.1 type IV conjugative transfer system pilin TraA -
H7R36_RS25610 () 125500..125580 + 81 Protein_154 type IV conjugative transfer system protein TraL -
H7R36_RS25615 () 125640..126337 + 698 Protein_155 IS1 family transposase IS1G Transposase
H7R36_RS25620 () 126385..126705 + 321 WP_001348757.1 conjugal transfer protein TrbA -
H7R36_RS25625 () 126832..127116 + 285 WP_001617873.1 type-F conjugative transfer system pilin chaperone TraQ -
H7R36_RS25630 () 127103..127648 + 546 WP_000059831.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
H7R36_RS25635 () 127578..127925 + 348 WP_011666494.1 P-type conjugative transfer protein TrbJ -
H7R36_RS25640 () 127873..128298 + 426 WP_001348758.1 F-type conjugal transfer protein TrbF -
H7R36_RS25645 () 128285..129658 + 1374 WP_000944328.1 conjugal transfer protein TraH -
H7R36_RS25650 () 129655..132474 + 2820 WP_001007062.1 conjugal transfer mating pair stabilization protein TraG -
H7R36_RS25655 () 132493..132990 + 498 WP_000605862.1 entry exclusion protein -
H7R36_RS25660 () 133022..133753 + 732 WP_000850429.1 complement resistance protein TraT -
H7R36_RS25665 () 133956..134189 + 234 Protein_165 hypothetical protein -
H7R36_RS25670 () 134219..135832 - 1614 WP_000080174.1 IS66 family transposase ISEc23 Transposase
H7R36_RS25675 () 135863..136213 - 351 WP_000624688.1 IS66 family transposase ISEc47 Transposase
H7R36_RS25680 () 136213..136644 - 432 WP_001758867.1 IS66 family transposase ISEc43 Transposase
H7R36_RS25685 () 136742..137284 + 543 WP_089455070.1 hypothetical protein -
H7R36_RS25690 () 137281..139479 + 2199 WP_024623315.1 type IV conjugative transfer system coupling protein TraD -
H7R36_RS25695 () 139479..144749 + 5271 WP_001617867.1 Multifunctional conjugation protein TraI Relaxase
H7R36_RS25700 () 144769..145515 + 747 WP_000205718.1 conjugal transfer pilus acetylase TraX -
H7R36_RS25705 () 145570..146130 + 561 WP_000139341.1 fertility inhibition protein FinO -
H7R36_RS25710 () 146261..146473 + 213 WP_013023861.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance