Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   EL079_RS07925 Genome accession   NZ_LR134283
Coordinates   1602924..1604870 (+) Length   648 a.a.
NCBI ID   WP_003032320.1    Uniprot ID   -
Organism   Streptococcus anginosus strain NCTC10713     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1597924..1609870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL079_RS07905 (NCTC10713_01623) argR 1598326..1598766 (+) 441 WP_003027809.1 arginine repressor -
  EL079_RS07910 (NCTC10713_01624) hexA 1599024..1601585 (+) 2562 WP_018543668.1 DNA mismatch repair protein MutS Machinery gene
  EL079_RS07915 (NCTC10713_01625) - 1601774..1602232 (-) 459 WP_003032341.1 DUF3021 domain-containing protein -
  EL079_RS07920 (NCTC10713_01626) - 1602229..1602669 (-) 441 WP_003032335.1 LytTR family DNA-binding domain-containing protein -
  EL079_RS07925 (NCTC10713_01627) hexB 1602924..1604870 (+) 1947 WP_003032320.1 DNA mismatch repair endonuclease MutL Machinery gene
  EL079_RS07930 (NCTC10713_01628) - 1605059..1605994 (+) 936 Protein_1510 IS30 family transposase -
  EL079_RS07935 (NCTC10713_01629) ruvA 1606065..1606655 (+) 591 WP_003031812.1 Holliday junction branch migration protein RuvA Machinery gene
  EL079_RS07940 (NCTC10713_01630) - 1606666..1607244 (+) 579 WP_003031817.1 DNA-3-methyladenine glycosylase I -
  EL079_RS07945 (NCTC10713_01631) - 1607347..1607760 (-) 414 WP_018543619.1 EamA family transporter -
  EL079_RS07955 (NCTC10713_01632) cinA 1608360..1609631 (+) 1272 WP_003031814.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73212.33 Da        Isoelectric Point: 5.0598

>NTDB_id=999947 EL079_RS07925 WP_003032320.1 1602924..1604870(+) (hexB) [Streptococcus anginosus strain NCTC10713]
MSKIIELPENLANQIAAGEVIERPSSVVKELIENSIDAGATQIIVEIEEAGLRSIQVIDNGEGIEHEEVSLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSRLTIETATSSGAHGTLLIAQGGEVETLEPSSCPRGTKIKVEDLFFNTPARLKY
MKSQQAELSHIVDVMNRLSLAHPEVAFTLVNDGKEMTRTAGTGNLRQAIAGIYGLTTAKKMIEISASDLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIRIDPYLADVNVHPTKQEVRISKERELMALISQ
AIAASLKEQDLIPDALENLAKSTINRAIKPEQTSLPLKENRLYYDKERNDFFVKPQVSEAQPSFEESARLDQQSADTDEL
NSKAASVKFAERQSPSYNQLDHPELDQASLERALDKLDGEETSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYREKIGDVDASQQQLLVPYIFEFPADDMLRLKQRMTLLEEVGVFLEEYGTNQFILREHPIWLKEEEIESAIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=999947 EL079_RS07925 WP_003032320.1 1602924..1604870(+) (hexB) [Streptococcus anginosus strain NCTC10713]
ATGTCAAAAATTATTGAACTACCAGAAAATCTTGCTAATCAGATTGCAGCAGGTGAGGTCATCGAGCGACCTAGCAGCGT
GGTCAAGGAGTTGATAGAGAATTCCATTGATGCTGGTGCCACTCAGATTATAGTTGAGATTGAAGAAGCGGGACTCAGGA
GCATTCAAGTCATTGATAATGGTGAAGGAATTGAGCATGAGGAGGTTTCCTTGGCTTTGCGGCGGCATGCTACTAGTAAA
ATCAAGAAACAAGCCGACCTGTTTCGGATTCGGACATTGGGTTTTCGCGGTGAGGCGCTTCCGTCCATTGCCTCTGTTTC
ACGTTTGACGATTGAAACTGCGACAAGTAGTGGTGCACATGGAACGCTTCTGATTGCGCAAGGTGGAGAAGTTGAGACTT
TAGAGCCAAGTAGCTGTCCTAGGGGTACCAAAATCAAAGTGGAAGACCTTTTTTTCAACACGCCTGCTCGTTTGAAATAT
ATGAAAAGTCAACAAGCGGAACTATCTCATATTGTAGATGTGATGAATCGTTTGAGCTTGGCTCATCCGGAGGTCGCTTT
CACTCTTGTTAATGACGGTAAAGAGATGACACGGACAGCAGGAACAGGAAATCTGCGTCAAGCAATTGCTGGCATTTATG
GACTGACAACAGCCAAAAAAATGATTGAAATTTCAGCATCTGATTTGGATTTTGAAGTATCAGGCTATATTAGTTTGCCA
GAATTAACAAGGGCTAATCGGAATTACATTACTATTCTCATCAATGGTCGCTACATCAAGAATTTCCTACTCAATCGAGC
TATTTTAGATGGATATGGTAGCAAGCTCATGGTGGGACGTTTCCCGATTGCTGTGATTGATATTCGGATTGACCCATATC
TTGCTGATGTTAATGTTCACCCGACCAAGCAAGAAGTGCGGATTTCAAAGGAGCGAGAGCTCATGGCCTTGATATCGCAA
GCTATTGCTGCAAGTTTGAAAGAGCAAGATTTGATTCCGGACGCATTAGAGAATTTAGCCAAATCAACCATTAACCGAGC
AATTAAGCCTGAGCAGACCAGCCTCCCTCTCAAAGAGAACCGACTTTATTACGATAAAGAAAGAAATGACTTCTTTGTGA
AACCACAAGTGTCAGAAGCTCAACCTTCTTTTGAGGAATCTGCTCGATTAGATCAACAATCTGCTGATACAGATGAACTC
AATTCAAAAGCTGCTTCTGTCAAATTTGCAGAAAGACAATCTCCTTCTTACAATCAACTAGATCATCCAGAGCTGGATCA
GGCGAGCTTAGAGAGAGCTTTAGATAAGCTAGATGGAGAAGAAACTTCAACGTTTCCAGAATTGGAATATTTCGGGCAAA
TGCACGGCACCTACCTTTTTGCTCAAGGAAACGGTGGTCTTTATATTATTGACCAACATGCAGCTCAAGAGCGAGTAAAG
TACGAATATTACCGCGAAAAAATCGGAGATGTAGATGCTAGTCAGCAGCAGCTTCTGGTTCCCTATATCTTTGAATTTCC
AGCTGATGATATGTTGCGTCTGAAACAACGAATGACTCTTTTAGAAGAAGTCGGTGTTTTCCTTGAAGAATACGGAACTA
ATCAATTTATTCTTCGTGAACATCCCATTTGGCTTAAGGAAGAGGAGATCGAATCAGCTATTTATGAGATGTGCGATATG
CTGCTTCTAACCAAGGAAGTCTCTATCAAGAAATATCGCGCTGAGCTAGCTATTATGATGAGTTGCAAACGCTCTATTAA
AGCCAATCACAGTTTAGATGACTATTCAGCGCGTGATTTGATTTTTCAGTTATCACAATGCGACAATCCCTACAACTGCC
CTCACGGTCGTCCCGTTTTGGTCAACTTCACAAAATCTGATATGGAAAAAATGTTCCGTCGGATTCAGGAAAATCATACC
AGCCTGAGAGAATTGGGGAAATACTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.042

100

0.772