Detailed information NTG0999946

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: EL079_RS07910
• Genome accession: NZ_LR134283
• Coordinates: 1599024..1601585 (+)
• Length: 853 a.a.
• NCBI ID: WP_018543668.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain NCTC10713
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1594024..1606585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL079_RS07890 (NCTC10713_01620)	-	1595439..1595948 (+)	510	WP_003032313.1	hypothetical protein	-
EL079_RS07895 (NCTC10713_01621)	nrdI	1596024..1596479 (+)	456	WP_003032317.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
EL079_RS07900 (NCTC10713_01622)	argS	1596534..1598222 (-)	1689	WP_003032324.1	arginine--tRNA ligase	-
EL079_RS07905 (NCTC10713_01623)	argR	1598326..1598766 (+)	441	WP_003027809.1	arginine repressor	-
EL079_RS07910 (NCTC10713_01624)	hexA	1599024..1601585 (+)	2562	WP_018543668.1	DNA mismatch repair protein MutS	Machinery gene
EL079_RS07915 (NCTC10713_01625)	-	1601774..1602232 (-)	459	WP_003032341.1	DUF3021 domain-containing protein	-
EL079_RS07920 (NCTC10713_01626)	-	1602229..1602669 (-)	441	WP_003032335.1	LytTR family DNA-binding domain-containing protein	-
EL079_RS07925 (NCTC10713_01627)	hexB	1602924..1604870 (+)	1947	WP_003032320.1	DNA mismatch repair endonuclease MutL	Machinery gene
EL079_RS07930 (NCTC10713_01628)	-	1605059..1605994 (+)	936	Protein_1510	IS30 family transposase	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 95877.51 Da
• Isoelectric Point: 5.1204

>NTDB_id=999946 EL079_RS07910 WP_018543668.1 1599024..1601585(+) (hexA) [Streptococcus anginosus strain NCTC10713]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDATNAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNI
VCGEIRNLRAREVVLGYELPEMERQVLETQMTLLLSQVETTFDDVQLLGKDLSPLEHQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLTENARTGKKHGSLYWLMDDTKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDTLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELASLIQSAISP
DASNVITEGNIIKTGFDETLDKYRVVMRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRANQILTRLESQANEKSSFGISNTL
PAAAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=999946 EL079_RS07910 WP_018543668.1 1599024..1601585(+) (hexA) [Streptococcus anginosus strain NCTC10713]
ATGACAAAAGAAAAACTATCTCCAGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGCTATT
TCGCATGGGAGATTTTTATGAATTATTCTATGATGATGCGACCAATGCGGCACAGATTTTAGAGATTGCTCTGACTAGTC
GCAATAAAAACTCGGAAAATCCAATCCCAATGGCAGGAGTTCCTTACCATTCAGTGCAGCAATACATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGACTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATA
GTCTGTGGAGAAATCCGAAACTTGCGAGCGCGTGAAGTGGTCTTAGGGTATGAATTGCCTGAAATGGAGCGCCAAGTATT
GGAGACTCAAATGACTCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCAC
CGCTAGAGCACCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGACTACTCAACTATGGCAAGTCTGGATTTAACAGAGAATGCTCG
GACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGATACCAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGAATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAGCGCAGTGACTTATCAGACACTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCAAAAGATTTATTACAACTTGCTGCGACATTGAGTCATGTACCACAAATTAAGGGAATCTTAAAAGGAATTGACA
GCCCAGTTTTGGAAGATTTGATTGCCAAATTGGATGAAATTCCTGAACTGGCGTCCTTAATTCAGTCAGCAATTTCGCCG
GATGCTTCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGATAAATATCGAGTGGTTAT
GCGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCCAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTTCATGTCACAAATTCCCAGCTTGAACACGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTCTGAAAAATTCAGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGGGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAGTATATCAAACGCCTGCAATCCTTGGCAC
AAACTCTGGCAACGGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCTGAAAAGCAACACTTTGTGAGACCAGAATTTATT
GAGCAACGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAACTAATTACAGGTCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCAATTATTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCTGAAAGCGCTCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGGTTGAAATGATGGAAGCAAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTTATTCTTTTTGATGAGTTAGGAAGAGGAACAGCGACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCGGACAGGAGCCAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGAATCAAATATTGACACGATTAGAAAGCCAAGCAAATGAGAAGTCATCTTTTGGCATCTCTAATACATTG
CCTGCGGCTGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (255-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.202	100	0.762
mutS	Pseudomonas stutzeri strain ATCC 17587	36.385	100	0.368