Detailed information NTG0999534

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: EL086_RS00305
• Genome accession: NZ_LR134274
• Coordinates: 52171..54702 (+)
• Length: 843 a.a.
• NCBI ID: WP_371212499.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NCTC8618
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 47171..59702

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL086_RS00285 (NCTC8618_02471)	-	47364..48665 (+)	1302	WP_038675005.1	hypothetical protein	-
EL086_RS00290 (NCTC8618_02472)	argS	49518..51209 (-)	1692	WP_038675007.1	arginine--tRNA ligase	-
EL086_RS00295 (NCTC8618_02473)	argR	51364..51792 (+)	429	WP_171963651.1	arginine repressor	-
EL086_RS00300 (NCTC8618_02474)	-	51792..52151 (+)	360	WP_038675011.1	YlbF family regulator	-
EL086_RS00305 (NCTC8618_02475)	hexA	52171..54702 (+)	2532	WP_371212499.1	DNA mismatch repair protein MutS	Machinery gene
EL086_RS00310 (NCTC8618_02476)	-	54736..55191 (-)	456	WP_002886315.1	DUF3021 domain-containing protein	-
EL086_RS00315 (NCTC8618_02477)	-	55188..55625 (-)	438	WP_038675015.1	LytTR family DNA-binding domain-containing protein	-
EL086_RS00320 (NCTC8618_02478)	-	55804..56106 (+)	303	WP_038675017.1	hypothetical protein	-
EL086_RS00325 (NCTC8618_02479)	hexB	56159..58102 (+)	1944	WP_038675019.1	DNA mismatch repair endonuclease MutL	Machinery gene
EL086_RS00330 (NCTC8618_02480)	-	58233..58454 (+)	222	WP_038675022.1	hypothetical protein	-
EL086_RS00335 (NCTC8618_02481)	ruvA	58611..59201 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94635.63 Da
• Isoelectric Point: 4.6360

>NTDB_id=999534 EL086_RS00305 WP_371212499.1 52171..54702(+) (hexA) [Streptococcus salivarius strain NCTC8618]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVVGYDLPEADEQILVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERYG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSHTNVQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=999534 EL086_RS00305 WP_371212499.1 52171..54702(+) (hexA) [Streptococcus salivarius strain NCTC8618]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTATCATTCAGCTCAATCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAGATTTTGGTCAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACCAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGCGAGCTCAGTCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTGTTGGAAAATGCTAGAACGGGCAAGAAACACGGTTCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGCACTTGGATTGATCGTCCTTTAGTGAATCAGG
CTGCAATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGACCTGACTGAGAGTCTT
AAAGGGGTTTACGATATTGAGCGCTTAGCCAGTCGAGTTTCCTTTGGCAAGGCTAATCCTAAAGATTTGATTCAACTAGG
TCATACCTTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATGATGAGGCCTTGTCACGTCTTTTACAAG
AATTGGATGCTCTGCCAGAATTAGAAAGTCTGATTCGGTCAGCTATTGATCCCGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGCGAGGGGACGTCATGGATTGCGGA
TATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAATCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAATTCAGAGCGCTATGGA
ACCGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAGTCATCAACGCTCGAATATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCCATTGCGACAGTCGATGTTCTTC
AGAGCTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGTCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCATACCAA
TGTTCAGCTCATCACAGGGCCAAATATGAGTGGTAAATCTACCTATATGCGTCAGTTGGCTTTGTCAGTCGTTATGGCTC
AGATGGGGGCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCTATCTATACACGTATTGGTGCTGCAGAT
GATCTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTAGGACGTGGGACAGCCACCTATGACGGTATGGCTCTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTTGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCCGA
TAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTGGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCTGCCACTGAAACGCATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTACGTGATTTGGACATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (590-776)

• MutS family domain IV (MutS_IV) (406-496)

• MutS domain I (MutS_I) (1-109)

• MutS domain III (MutS_III) (247-537)

• MutS domain II (MutS_II) (117-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.815	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	35.731	100	0.365