Detailed information NTG0999017

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ABD412_RS02285
• Genome accession: NZ_CP155737
• Coordinates: 425922..426923 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain 9606/11
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 420922..431923

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABD412_RS02260 (ABD412_02245)	-	421598..422281 (-)	684	WP_012560521.1	DUF969 domain-containing protein	-
ABD412_RS02265 (ABD412_02250)	-	422490..423416 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ABD412_RS02270 (ABD412_02255)	-	423561..423938 (-)	378	WP_002985686.1	VOC family protein	-
ABD412_RS02275 (ABD412_02260)	-	423940..424614 (-)	675	WP_023612169.1	NAD(P)H-dependent oxidoreductase	-
ABD412_RS02280 (ABD412_02265)	-	424663..425748 (-)	1086	WP_023612158.1	aminopeptidase P family protein	-
ABD412_RS02285 (ABD412_02270)	ccpA	425922..426923 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ABD412_RS02290 (ABD412_02275)	-	427053..428051 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ABD412_RS02295 (ABD412_02280)	-	428053..429387 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ABD412_RS02300 (ABD412_02285)	thrS	429809..431752 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=999017 ABD412_RS02285 WP_002985680.1 425922..426923(+) (ccpA) [Streptococcus pyogenes strain 9606/11]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=999017 ABD412_RS02285 WP_002985680.1 425922..426923(+) (ccpA) [Streptococcus pyogenes strain 9606/11]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCCGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559