Detailed information NTG0998903

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ABD408_RS02220
• Genome accession: NZ_CP155735
• Coordinates: 420054..421055 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain 4958/15
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 415054..426055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABD408_RS02195 (ABD408_02180)	-	415730..416413 (-)	684	WP_012560521.1	DUF969 domain-containing protein	-
ABD408_RS02200 (ABD408_02185)	-	416622..417548 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ABD408_RS02205 (ABD408_02190)	-	417693..418070 (-)	378	WP_002985686.1	VOC family protein	-
ABD408_RS02210 (ABD408_02195)	-	418072..418746 (-)	675	WP_023612169.1	NAD(P)H-dependent oxidoreductase	-
ABD408_RS02215 (ABD408_02200)	-	418795..419880 (-)	1086	WP_023612158.1	aminopeptidase P family protein	-
ABD408_RS02220 (ABD408_02205)	ccpA	420054..421055 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ABD408_RS02225 (ABD408_02210)	-	421185..422183 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ABD408_RS02230 (ABD408_02215)	-	422185..423519 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ABD408_RS02235 (ABD408_02220)	thrS	423941..425884 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=998903 ABD408_RS02220 WP_002985680.1 420054..421055(+) (ccpA) [Streptococcus pyogenes strain 4958/15]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=998903 ABD408_RS02220 WP_002985680.1 420054..421055(+) (ccpA) [Streptococcus pyogenes strain 4958/15]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCCGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559