Detailed information NTG0998826

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ABD411_RS00685
• Genome accession: NZ_CP155734
• Coordinates: 104528..104962 (+)
• Length: 144 a.a.
• NCBI ID: WP_023612536.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 8373/17
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99528..109962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABD411_RS00655 (ABD411_00645)	-	101197..101562 (+)	366	WP_002986560.1	DUF1033 family protein	-
ABD411_RS00660 (ABD411_00650)	comYA	101655..102593 (+)	939	WP_023612548.1	competence type IV pilus ATPase ComGA	Machinery gene
ABD411_RS00665 (ABD411_00655)	comYB	102529..103563 (+)	1035	WP_229363300.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABD411_RS00670 (ABD411_00660)	comYC	103565..103891 (+)	327	WP_032465607.1	competence type IV pilus major pilin ComGC	Machinery gene
ABD411_RS00675 (ABD411_00665)	comGD	103866..104294 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
ABD411_RS00680 (ABD411_00670)	comGE	104251..104535 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
ABD411_RS00685 (ABD411_00675)	comYF	104528..104962 (+)	435	WP_023612536.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABD411_RS00690 (ABD411_00680)	comGG	104946..105272 (+)	327	WP_002992739.1	competence type IV pilus minor pilin ComGG	-
ABD411_RS00695 (ABD411_00685)	comYH	105370..106323 (+)	954	WP_002987790.1	class I SAM-dependent methyltransferase	Machinery gene
ABD411_RS00700 (ABD411_00690)	-	106382..107578 (+)	1197	WP_023612537.1	acetate kinase	-
ABD411_RS00705 (ABD411_00695)	-	107765..108073 (+)	309	WP_032465606.1	hypothetical protein	-
ABD411_RS00710 (ABD411_00700)	proC	108156..108926 (-)	771	WP_002986527.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16688.29 Da
• Isoelectric Point: 10.2526

>NTDB_id=998826 ABD411_RS00685 WP_023612536.1 104528..104962(+) (comYF) [Streptococcus pyogenes strain 8373/17]
MSKQLSNIKAFTFLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=998826 ABD411_RS00685 WP_023612536.1 104528..104962(+) (comYF) [Streptococcus pyogenes strain 8373/17]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCTTTCTAGAGGCGTTAATAGCCTTACTCGTGATCTCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	50.36	96.528	0.486
comYF	Streptococcus mutans UA159	49.64	96.528	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	93.056	0.403
comGF/cglF	Streptococcus pneumoniae Rx1	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae D39	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae R6	42.105	92.361	0.389
comGF/cglF	Streptococcus pneumoniae TIGR4	42.105	92.361	0.389
comGF/cglF	Streptococcus mitis SK321	41.353	92.361	0.382