Detailed information NTG0998802

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ABFB49_RS23170
• Genome accession: NZ_CP155726
• Coordinates: 5003833..5005170 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain 2024CK-00357
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 4998833..5010170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABFB49_RS23145 (ABFB49_23145)	pgeF	4998976..4999704 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
ABFB49_RS23150 (ABFB49_23150)	rluD	4999701..5000663 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
ABFB49_RS23155 (ABFB49_23155)	-	5000809..5001834 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
ABFB49_RS23160 (ABFB49_23160)	-	5001991..5002236 (+)	246	WP_003102591.1	PP0621 family protein	-
ABFB49_RS23165 (ABFB49_23165)	pilS	5002226..5003818 (+)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
ABFB49_RS23170 (ABFB49_23170)	pilR	5003833..5005170 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
ABFB49_RS23175 (ABFB49_23175)	thiO	5005216..5006310 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
ABFB49_RS23180 (ABFB49_23180)	-	5006445..5006954 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
ABFB49_RS23185 (ABFB49_23185)	-	5007060..5007566 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
ABFB49_RS23190 (ABFB49_23190)	pilV	5007557..5008114 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
ABFB49_RS23195 (ABFB49_23195)	pilW	5008111..5008935 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
ABFB49_RS23200 (ABFB49_23200)	pilX	5008932..5009519 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=998802 ABFB49_RS23170 WP_003094694.1 5003833..5005170(+) (pilR) [Pseudomonas aeruginosa strain 2024CK-00357]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=998802 ABFB49_RS23170 WP_003094694.1 5003833..5005170(+) (pilR) [Pseudomonas aeruginosa strain 2024CK-00357]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGTGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCACCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAAAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTATACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCACTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384