Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EL118_RS09660 Genome accession   NZ_LR134228
Coordinates   1999148..2000980 (+) Length   610 a.a.
NCBI ID   WP_126509192.1    Uniprot ID   -
Organism   Escherichia coli strain NCTC9699     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1994148..2005980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL118_RS09620 (NCTC9699_01922) dcyD 1994375..1995361 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  EL118_RS09625 (NCTC9699_01923) tcyL 1995376..1996044 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EL118_RS09630 (NCTC9699_01924) tcyN 1996041..1996793 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EL118_RS09635 (NCTC9699_01925) sdiA 1997023..1997745 (+) 723 WP_032291441.1 transcriptional regulator SdiA -
  EL118_RS09640 (NCTC9699_01926) yecF 1997812..1998036 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EL118_RS09645 yecU 1998023..1998199 (-) 177 WP_000590344.1 protein YecU -
  EL118_RS24810 - 1998237..1998353 (-) 117 WP_001302039.1 hypothetical protein -
  EL118_RS09655 (NCTC9699_01927) letA 1998495..1999151 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EL118_RS09660 (NCTC9699_01928) uvrC 1999148..2000980 (+) 1833 WP_126509192.1 excinuclease ABC subunit UvrC Machinery gene
  EL118_RS09665 (NCTC9699_01929) pgsA 2001037..2001585 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EL118_RS09685 (NCTC9699_01933) yecA 2002234..2002899 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  EL118_RS09690 (NCTC9699_01934) tyrP 2002961..2004172 (-) 1212 WP_000797573.1 tyrosine transporter TyrP -
  EL118_RS09695 (NCTC9699_01935) yecH 2004362..2004601 (+) 240 WP_000377225.1 YecH family metal-binding protein -
  EL118_RS09700 (NCTC9699_01936) ftnA 2004639..2005136 (-) 498 WP_000917208.1 non-heme ferritin -
  EL118_RS09705 (NCTC9699_01937) yecR 2005307..2005630 (-) 324 WP_001237869.1 YecR-like lipofamily protein -
  EL118_RS09710 azuC 2005893..2005979 (+) 87 WP_010723106.1 stress response protein AzuC -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68230.11 Da        Isoelectric Point: 9.3685

>NTDB_id=998727 EL118_RS09660 WP_126509192.1 1999148..2000980(+) (uvrC) [Escherichia coli strain NCTC9699]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQIEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGVDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=998727 EL118_RS09660 WP_126509192.1 1999148..2000980(+) (uvrC) [Escherichia coli strain NCTC9699]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGATCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTTACAGCACTTGCCAGTGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGTAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.993

99.672

0.379
  uvrC Streptococcus pneumoniae R6

37.664

99.672

0.375
  uvrC Streptococcus pneumoniae D39

37.664

99.672

0.375

Multiple sequence alignment