Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EL118_RS09655 Genome accession   NZ_LR134228
Coordinates   1998495..1999151 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain NCTC9699     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1993495..2004151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL118_RS09620 (NCTC9699_01922) dcyD 1994375..1995361 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  EL118_RS09625 (NCTC9699_01923) tcyL 1995376..1996044 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EL118_RS09630 (NCTC9699_01924) tcyN 1996041..1996793 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EL118_RS09635 (NCTC9699_01925) sdiA 1997023..1997745 (+) 723 WP_032291441.1 transcriptional regulator SdiA -
  EL118_RS09640 (NCTC9699_01926) yecF 1997812..1998036 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EL118_RS09645 yecU 1998023..1998199 (-) 177 WP_000590344.1 protein YecU -
  EL118_RS24810 - 1998237..1998353 (-) 117 WP_001302039.1 hypothetical protein -
  EL118_RS09655 (NCTC9699_01927) letA 1998495..1999151 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EL118_RS09660 (NCTC9699_01928) uvrC 1999148..2000980 (+) 1833 WP_126509192.1 excinuclease ABC subunit UvrC Machinery gene
  EL118_RS09665 (NCTC9699_01929) pgsA 2001037..2001585 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EL118_RS09685 (NCTC9699_01933) yecA 2002234..2002899 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=998726 EL118_RS09655 WP_000611328.1 1998495..1999151(+) (letA) [Escherichia coli strain NCTC9699]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=998726 EL118_RS09655 WP_000611328.1 1998495..1999151(+) (letA) [Escherichia coli strain NCTC9699]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment