Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   L282_RS08160 Genome accession   NZ_CP005930
Coordinates   1612410..1613042 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli APEC IMT5155     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1607410..1618042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L282_RS08130 (L282_1585) yheS 1607579..1609492 (+) 1914 WP_000634747.1 ABC transporter ATP-binding protein -
  L282_RS08135 (L282_1586) yheT 1609492..1610514 (+) 1023 WP_000057415.1 hydrolase -
  L282_RS08140 (L282_1587) yheU 1610508..1610726 (+) 219 WP_000907086.1 YheU family protein -
  L282_RS08145 (L282_1588) prkB 1610780..1611649 (+) 870 WP_001274684.1 phosphoribulokinase -
  L282_RS08150 (L282_1589) yhfA 1611704..1612108 (-) 405 WP_001148908.1 OsmC family protein -
  L282_RS08160 (L282_1590) crp 1612410..1613042 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  L282_RS08165 (L282_1591) yhfK 1613093..1615183 (+) 2091 WP_039267715.1 YccS/YhfK family putative transporter -
  L282_RS08170 (L282_1592) argD 1615250..1616470 (-) 1221 WP_000963803.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  L282_RS08175 (L282_1593) pabA 1616556..1617119 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  L282_RS08180 (L282_1594) fic 1617151..1617753 (-) 603 WP_039267716.1 putative adenosine monophosphate-protein transferase Fic -
  L282_RS08185 yhfG 1617743..1617910 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=99812 L282_RS08160 WP_000242755.1 1612410..1613042(+) (crp) [Escherichia coli APEC IMT5155]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=99812 L282_RS08160 WP_000242755.1 1612410..1613042(+) (crp) [Escherichia coli APEC IMT5155]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment