Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   ABC799_RS07295 Genome accession   NZ_CP155534
Coordinates   1391993..1393327 (-) Length   444 a.a.
NCBI ID   WP_000491795.1    Uniprot ID   A0AAJ5P3Y0
Organism   Streptococcus pneumoniae strain DCC1476     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1386993..1398327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC799_RS07280 (ABC799_07280) - 1387953..1390403 (-) 2451 WP_000848697.1 bifunctional DnaQ family exonuclease/ATP-dependent helicase -
  ABC799_RS07285 (ABC799_07285) - 1390603..1391532 (-) 930 WP_000411847.1 peptidase U32 family protein -
  ABC799_RS07290 (ABC799_07290) - 1391672..1391959 (+) 288 WP_001145225.1 DUF3270 domain-containing protein -
  ABC799_RS07295 (ABC799_07295) ciaH 1391993..1393327 (-) 1335 WP_000491795.1 two-component system sensor histidine kinase CiaH Regulator
  ABC799_RS07300 (ABC799_07300) ciaR 1393317..1393991 (-) 675 WP_000590640.1 two-component system response regulator CiaR Regulator
  ABC799_RS07305 (ABC799_07305) - 1394187..1395443 (+) 1257 WP_000530081.1 ISL3 family transposase -
  ABC799_RS07310 (ABC799_07310) - 1395522..1398068 (-) 2547 Protein_1395 M1 family metallopeptidase -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 50672.40 Da        Isoelectric Point: 9.3547

>NTDB_id=997278 ABC799_RS07295 WP_000491795.1 1391993..1393327(-) (ciaH) [Streptococcus pneumoniae strain DCC1476]
MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLYTSVDDKLHGLSENPQAVIQLAINRATEEIKDLENAR
ADASKVEIKPNVSSNTEVILFDKDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQSFVENASHELRTPLAVLQNRLE
TLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLNLARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRI
HRTIVTDQLLLKQLMTILFDNAVKYTEEDGEINFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKARTRQKGGF
GLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=997278 ABC799_RS07295 WP_000491795.1 1391993..1393327(-) (ciaH) [Streptococcus pneumoniae strain DCC1476]
ATGTTCAGTAAACTTAAAAAAACATGGTATGCGGATGACTTTAGTTATTTTATCCGCAACTTCGGTGTCTTCACCCTGAT
TTTTTCTACAATGACTCTGATTATTTTACAAGTCATGCATTCGAGTCTTTATACTTCGGTGGACGATAAGCTTCATGGAC
TGAGTGAAAATCCTCAAGCAGTTATTCAGCTGGCTATAAATAGGGCAACAGAAGAGATTAAAGATTTAGAAAATGCTAGG
GCGGACGCTAGTAAAGTAGAAATAAAACCTAATGTCAGTTCCAATACGGAAGTCATTCTCTTTGATAAAGACTTTACTCA
ACTTCTTTCTGGAAATCGATTTTTGGGCTTGGATAAGATTAAGTTAGAAAAGAAAGAACTAGGACATATCTACCAGATTC
AGGTTTTTAATAGCTATGGGCAGGAAGAAATCTATCGTGTGATTTTGATGGAGACCAATATTAGTTCGGTTTCAACCAAT
ATCAAGTATGCTGCTGTCTTGATTAATACCAGTCAGTTGGAGCAGGCTAGTCAAAAGCATGAGCAATTGATTGTGGTCGT
GATGGCTAGTTTCTGGATTTTGTCTTTACTTGCCAGTCTCTATCTAGCTAGGGTCAGTGTTAGGCCCCTGCTTGAGAGTA
TGCAGAAGCAACAGTCTTTTGTGGAAAATGCCAGTCATGAGTTACGAACTCCACTCGCAGTTTTGCAAAATCGCTTAGAG
ACCCTTTTTCGTAAGCCAGAAGCTACCATTATGGATGTGAGCGAAAGCATTGCATCGAGTTTGGAAGAAGTCCGAAATAT
GCGTTTTTTAACGACAAGCTTGCTGAACTTAGCTCGGAGAGATGATGGGATTAAGCCGGAGCTTGCAGAAGTTCCAACTA
GCTTTTTTAATACAACTTTCACAAACTACGAGATGATTGCTTCGGAAAATAATCGTGTCTTCCGTTTTGAAAATCGTATC
CATCGAACAATTGTCACAGATCAGCTTCTTCTGAAACAACTGATGACCATTCTTTTCGATAATGCCGTCAAGTATACTGA
GGAGGATGGTGAAATTAATTTTCTTATCTCGGCGACCGATCGCAATCTTTATTTACTTGTTTCTGATAATGGAATCGGTA
TTTCGACAGAAGATAAAAAGAAAATTTTTGACCGTTTTTATCGAGTAGACAAAGCTAGAACCCGGCAAAAAGGTGGTTTT
GGTTTAGGATTATCCCTAGCCAAGCAAATTGTAGATGCTCTAAAAGGAACTGTTACTGTCAAAGATAATAAACCCAAGGG
AACAATCTTTGAAGTGAAGATTGCCATTCAGACACCATCTAAAAAGAAAAAATAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(327-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(217-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

99.775

100

0.998
  ciaH Streptococcus pneumoniae D39

99.775

100

0.998
  ciaH Streptococcus pneumoniae R6

99.775

100

0.998
  ciaH Streptococcus pneumoniae TIGR4

99.775

100

0.998
  ciaH Streptococcus mutans UA159

55.632

97.973

0.545

Multiple sequence alignment