Detailed information NTG0997242

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ABC799_RS01465
• Genome accession: NZ_CP155534
• Coordinates: 270214..271224 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain DCC1476
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 265214..276224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC799_RS01435 (ABC799_01435)	-	266085..266291 (+)	207	Protein_253	hypothetical protein	-
ABC799_RS01440 (ABC799_01440)	-	266288..266482 (+)	195	WP_000715302.1	hypothetical protein	-
ABC799_RS01445 (ABC799_01445)	-	266469..267353 (+)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
ABC799_RS01450 (ABC799_01450)	-	267355..268092 (+)	738	WP_000832916.1	ABC transporter permease	-
ABC799_RS01455 (ABC799_01455)	-	268092..269189 (+)	1098	WP_000893503.1	sensor histidine kinase	-
ABC799_RS01460 (ABC799_01460)	-	269190..269789 (+)	600	WP_000866703.1	response regulator transcription factor	-
ABC799_RS01465 (ABC799_01465)	ccpA	270214..271224 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
ABC799_RS01470 (ABC799_01470)	-	271288..271671 (+)	384	WP_001092022.1	hypothetical protein	-
ABC799_RS01475 (ABC799_01475)	-	271700..272662 (-)	963	WP_001124786.1	asparaginase	-
ABC799_RS01480 (ABC799_01480)	-	272728..274116 (+)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
ABC799_RS01485 (ABC799_01485)	-	274151..274603 (-)	453	WP_000079148.1	universal stress protein	-
ABC799_RS01490 (ABC799_01490)	-	274765..275059 (+)	295	Protein_264	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=997242 ABC799_RS01465 WP_000990607.1 270214..271224(+) (ccpA) [Streptococcus pneumoniae strain DCC1476]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=997242 ABC799_RS01465 WP_000990607.1 270214..271224(+) (ccpA) [Streptococcus pneumoniae strain DCC1476]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568