Detailed information NTG0997195

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ABC814_RS09970
• Genome accession: NZ_CP155533
• Coordinates: 1926842..1927852 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain Spn1439-106
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1921842..1932852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC814_RS09945 (ABC814_09945)	-	1923053..1923346 (-)	294	WP_000977365.1	hypothetical protein	-
ABC814_RS09950 (ABC814_09950)	-	1923508..1923960 (+)	453	WP_000079148.1	universal stress protein	-
ABC814_RS09955 (ABC814_09955)	-	1923995..1925383 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
ABC814_RS09960 (ABC814_09960)	-	1925449..1926411 (+)	963	WP_001124777.1	asparaginase	-
ABC814_RS09965 (ABC814_09965)	-	1926440..1926778 (-)	339	WP_001092039.1	hypothetical protein	-
ABC814_RS09970 (ABC814_09970)	ccpA	1926842..1927852 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
ABC814_RS09975 (ABC814_09975)	-	1928277..1928876 (-)	600	WP_000866724.1	response regulator transcription factor	-
ABC814_RS09980 (ABC814_09980)	-	1928878..1929975 (-)	1098	WP_000893549.1	sensor histidine kinase	-
ABC814_RS09985 (ABC814_09985)	-	1929975..1930712 (-)	738	WP_000832836.1	ABC transporter permease	-
ABC814_RS09990 (ABC814_09990)	-	1930714..1931598 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
ABC814_RS09995 (ABC814_09995)	-	1931585..1931779 (-)	195	WP_000715301.1	hypothetical protein	-
ABC814_RS10000 (ABC814_10000)	-	1931776..1931982 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=997195 ABC814_RS09970 WP_000990607.1 1926842..1927852(-) (ccpA) [Streptococcus pneumoniae strain Spn1439-106]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=997195 ABC814_RS09970 WP_000990607.1 1926842..1927852(-) (ccpA) [Streptococcus pneumoniae strain Spn1439-106]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCTTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568