Detailed information NTG0997088

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ABC810_RS01375
• Genome accession: NZ_CP155532
• Coordinates: 263472..264482 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain SP264
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 258472..269482

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC810_RS01345 (ABC810_01345)	-	259342..259548 (+)	207	Protein_235	hypothetical protein	-
ABC810_RS01350 (ABC810_01350)	-	259545..259739 (+)	195	WP_000820189.1	hypothetical protein	-
ABC810_RS01355 (ABC810_01355)	-	259726..260610 (+)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
ABC810_RS01360 (ABC810_01360)	-	260612..261349 (+)	738	WP_000832916.1	ABC transporter permease	-
ABC810_RS01365 (ABC810_01365)	-	261349..262446 (+)	1098	WP_000893500.1	sensor histidine kinase	-
ABC810_RS01370 (ABC810_01370)	-	262448..263047 (+)	600	WP_000866719.1	response regulator transcription factor	-
ABC810_RS01375 (ABC810_01375)	ccpA	263472..264482 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
ABC810_RS01380 (ABC810_01380)	-	264688..265650 (-)	963	WP_001124777.1	asparaginase	-
ABC810_RS01385 (ABC810_01385)	-	265716..267104 (+)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
ABC810_RS01390 (ABC810_01390)	-	267139..267591 (-)	453	WP_000079148.1	universal stress protein	-
ABC810_RS01395 (ABC810_01395)	-	267753..268046 (+)	294	WP_000977368.1	hypothetical protein	-
ABC810_RS01400 (ABC810_01400)	-	268202..269416 (+)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=997088 ABC810_RS01375 WP_000990607.1 263472..264482(+) (ccpA) [Streptococcus pneumoniae strain SP264]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=997088 ABC810_RS01375 WP_000990607.1 263472..264482(+) (ccpA) [Streptococcus pneumoniae strain SP264]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568