Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EL018_RS09090 Genome accession   NZ_LR134082
Coordinates   1879984..1880640 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain NCTC9038     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1874984..1885640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL018_RS09055 (NCTC9038_01837) dcyD 1875864..1876850 (+) 987 WP_032265403.1 D-cysteine desulfhydrase -
  EL018_RS09060 (NCTC9038_01838) tcyL 1876865..1877533 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EL018_RS09065 (NCTC9038_01839) tcyN 1877530..1878282 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EL018_RS09070 (NCTC9038_01840) sdiA 1878512..1879234 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  EL018_RS09075 (NCTC9038_01841) yecF 1879301..1879525 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EL018_RS09080 yecU 1879512..1879688 (-) 177 WP_000590344.1 protein YecU -
  EL018_RS23395 - 1879726..1879842 (-) 117 WP_001302039.1 hypothetical protein -
  EL018_RS09090 (NCTC9038_01842) letA 1879984..1880640 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EL018_RS09095 (NCTC9038_01843) uvrC 1880637..1882469 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EL018_RS09100 (NCTC9038_01844) pgsA 1882526..1883074 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EL018_RS09120 (NCTC9038_01848) yecA 1883724..1884389 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=997041 EL018_RS09090 WP_000611335.1 1879984..1880640(+) (letA) [Escherichia coli strain NCTC9038]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=997041 EL018_RS09090 WP_000611335.1 1879984..1880640(+) (letA) [Escherichia coli strain NCTC9038]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment