Detailed information NTG0994404

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: AAYT22_RS09285
• Genome accession: NZ_CP154876
• Coordinates: 1792770..1793072 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20155336
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1787770..1798072

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT22_RS09250 (AAYT22_09240)	rnpA	1788449..1788820 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AAYT22_RS09255 (AAYT22_09245)	-	1788837..1788968 (-)	132	WP_000768904.1	hypothetical protein	-
AAYT22_RS09260 (AAYT22_09250)	-	1788969..1790159 (-)	1191	WP_000167753.1	acetate kinase	-
AAYT22_RS09265 (AAYT22_09255)	comYH	1790210..1791163 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
AAYT22_RS09270 (AAYT22_09260)	-	1791224..1791818 (-)	595	Protein_1799	class I SAM-dependent methyltransferase	-
AAYT22_RS09275 (AAYT22_09265)	comGG/cglG	1791955..1792368 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
AAYT22_RS09280 (AAYT22_09270)	comGF/cglF	1792346..1792807 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
AAYT22_RS09285 (AAYT22_09275)	comGE/cglE	1792770..1793072 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AAYT22_RS09290 (AAYT22_09280)	comGD/cglD	1793035..1793439 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
AAYT22_RS09295 (AAYT22_09285)	comGC/cglC	1793432..1793758 (-)	327	WP_000738631.1	comG operon protein ComGC	Machinery gene
AAYT22_RS09300 (AAYT22_09290)	comGB/cglB	1793760..1794776 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
AAYT22_RS09305 (AAYT22_09295)	comGA/cglA/cilD	1794724..1795665 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
AAYT22_RS09310 (AAYT22_09300)	-	1795741..1796106 (-)	366	WP_000286415.1	DUF1033 family protein	-
AAYT22_RS09315 (AAYT22_09305)	-	1796257..1797315 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=994404 AAYT22_RS09285 WP_000413382.1 1792770..1793072(-) (comGE/cglE) [Streptococcus pneumoniae strain 20155336]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=994404 AAYT22_RS09285 WP_000413382.1 1792770..1793072(-) (comGE/cglE) [Streptococcus pneumoniae strain 20155336]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4