Detailed information NTG0994398

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: AAYT22_RS08980
• Genome accession: NZ_CP154876
• Coordinates: 1743401..1744411 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 20155336
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1738401..1749411

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT22_RS08955 (AAYT22_08945)	-	1739701..1739994 (-)	294	WP_000977369.1	hypothetical protein	-
AAYT22_RS08960 (AAYT22_08950)	-	1740156..1740608 (+)	453	WP_000079148.1	universal stress protein	-
AAYT22_RS08965 (AAYT22_08955)	-	1740643..1742031 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
AAYT22_RS08970 (AAYT22_08960)	-	1742097..1743059 (+)	963	WP_001124779.1	asparaginase	-
AAYT22_RS08975 (AAYT22_08965)	-	1743056..1743337 (-)	282	WP_001092043.1	hypothetical protein	-
AAYT22_RS08980 (AAYT22_08970)	ccpA	1743401..1744411 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
AAYT22_RS08985 (AAYT22_08975)	-	1744836..1745435 (-)	600	WP_000866731.1	response regulator transcription factor	-
AAYT22_RS08990 (AAYT22_08980)	-	1745436..1746533 (-)	1098	WP_000893510.1	sensor histidine kinase	-
AAYT22_RS08995 (AAYT22_08985)	-	1746533..1747270 (-)	738	WP_061842847.1	ABC transporter permease	-
AAYT22_RS09000 (AAYT22_08990)	-	1747272..1748156 (-)	885	WP_000219357.1	ABC transporter ATP-binding protein	-
AAYT22_RS09005 (AAYT22_08995)	-	1748143..1748337 (-)	195	WP_000820180.1	hypothetical protein	-
AAYT22_RS09010 (AAYT22_09000)	-	1748334..1748540 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=994398 AAYT22_RS08980 WP_000990607.1 1743401..1744411(-) (ccpA) [Streptococcus pneumoniae strain 20155336]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=994398 AAYT22_RS08980 WP_000990607.1 1743401..1744411(-) (ccpA) [Streptococcus pneumoniae strain 20155336]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568