Detailed information NTG0993985

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: EQB47_RS02705
• Genome accession: NZ_LR129844
• Coordinates: 489555..490292 (+)
• Length: 245 a.a.
• NCBI ID: WP_001219127.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 180-15 isolate 180-15
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 484555..495292

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB47_RS02670	-	485531..485725 (-)	195	WP_001808905.1	hypothetical protein	-
EQB47_RS02675	-	485887..486174 (-)	288	WP_000777760.1	hypothetical protein	-
EQB47_RS02680	-	486184..486594 (-)	411	WP_001278301.1	HIT family protein	-
EQB47_RS02685	pptA	486662..487393 (+)	732	WP_000889923.1	ABC transporter ATP-binding protein	Regulator
EQB47_RS02690	pptB	487390..488439 (+)	1050	WP_000653752.1	ABC transporter permease	Regulator
EQB47_RS02695	-	488607..488936 (-)	330	WP_000132570.1	hypothetical protein	-
EQB47_RS02700	-	489212..489550 (+)	339	WP_000682119.1	LytTR family DNA-binding domain-containing protein	-
EQB47_RS02705	comE/blpR	489555..490292 (+)	738	WP_001219127.1	response regulator transcription factor	Regulator
EQB47_RS02710	-	490306..491646 (+)	1341	WP_001017622.1	sensor histidine kinase	-
EQB47_RS02715	blpC	491688..491843 (-)	156	WP_000358813.1	quorum-sensing system pheromone BlpC	-
EQB47_RS02720	-	491900..493261 (-)	1362	WP_001069092.1	bacteriocin secretion accessory protein	-
EQB47_RS11975	comA/nlmT	493272..493760 (-)	489	WP_307774349.1	ATP-binding cassette domain-containing protein	Regulator
EQB47_RS11980	comA/nlmT	493744..494184 (-)	441	WP_001808911.1	ATP-binding cassette domain-containing protein	Regulator
EQB47_RS11985	comA/nlmT	494174..494899 (-)	726	WP_167750760.1	ABC transporter transmembrane domain-containing protein	Regulator

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28683.81 Da
• Isoelectric Point: 6.0431

>NTDB_id=993985 EQB47_RS02705 WP_001219127.1 489555..490292(+) (comE/blpR) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPSLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide

• Length: 738 bp

>NTDB_id=993985 EQB47_RS02705 WP_001219127.1 489555..490292(+) (comE/blpR) [Streptococcus pneumoniae strain 180-15 isolate 180-15]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCAGAGGTACATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTAGCTAGAAAGATTCGGGAACAAGAC
CCTTATGCCCTAATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCTCTGTCCTTTCGCTACCAAGTGTCAGCTTTGGA
CTACATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAATATCCTTTCAAAGAGGTTTACTAT
CTCGAAACATCCCCAAGACCCCATCGTGTTATTCTCTATACCAAGACGGACAGGCTAGAATTTACGGCGAGTTTAGAGGA
GGTTTTTAAGCAGGAACCCAGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTCCTTTTCTTTCCCAATGGTGGAAGCTGTCTGATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (3-122)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.498	99.184	0.531
comE/comE1	Streptococcus equinus JB1	43.46	96.735	0.42
comE/comE2	Streptococcus equinus JB1	38.843	98.776	0.384