Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   AAIS09_RS09795 Genome accession   NZ_CP154595
Coordinates   1910326..1911033 (+) Length   235 a.a.
NCBI ID   WP_000166475.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain serotype 4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1905326..1916033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAIS09_RS09775 (AAIS09_09760) argR 1906626..1907072 (-) 447 WP_001231473.1 arginine repressor -
  AAIS09_RS09780 (AAIS09_09765) argS 1907208..1908899 (+) 1692 WP_001092738.1 arginine--tRNA ligase -
  AAIS09_RS09785 (AAIS09_09770) - 1909214..1909771 (-) 558 Protein_1886 transposase family protein -
  AAIS09_RS09790 (AAIS09_09775) - 1909757..1910242 (+) 486 WP_001826677.1 cupin domain-containing protein -
  AAIS09_RS09795 (AAIS09_09780) vicR 1910326..1911033 (+) 708 WP_000166475.1 response regulator transcription factor Regulator
  AAIS09_RS09800 (AAIS09_09785) pnpS 1911034..1912365 (+) 1332 WP_000833268.1 two-component system histidine kinase PnpS -
  AAIS09_RS09805 (AAIS09_09790) - 1912532..1913407 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  AAIS09_RS09810 (AAIS09_09795) pstC 1913525..1914388 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  AAIS09_RS09815 (AAIS09_09800) pstA 1914381..1915196 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  AAIS09_RS09820 (AAIS09_09805) pstB 1915198..1915950 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27230.61 Da        Isoelectric Point: 6.6568

>NTDB_id=993720 AAIS09_RS09795 WP_000166475.1 1910326..1911033(+) (vicR) [Streptococcus pneumoniae strain serotype 4]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=993720 AAIS09_RS09795 WP_000166475.1 1910326..1911033(+) (vicR) [Streptococcus pneumoniae strain serotype 4]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTGACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTGAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGTTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(159-232)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

48.707

98.723

0.481
  micA Streptococcus pneumoniae Cp1015

47.845

98.723

0.472
  covR Lactococcus lactis subsp. lactis strain DGCC12653

40.773

99.149

0.404
  covR Streptococcus salivarius strain HSISS4

39.744

99.574

0.396

Multiple sequence alignment