Detailed information NTG0993696

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AAIS09_RS08630
• Genome accession: NZ_CP154595
• Coordinates: 1719240..1720307 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain serotype 4
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1714240..1725307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAIS09_RS08605 (AAIS09_08590)	treR	1714430..1715140 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
AAIS09_RS08610 (AAIS09_08595)	-	1715172..1715975 (-)	804	WP_050091315.1	ABC transporter ATP-binding protein	-
AAIS09_RS08615 (AAIS09_08600)	-	1715988..1716865 (-)	878	Protein_1705	ABC transporter permease	-
AAIS09_RS08620 (AAIS09_08605)	-	1716877..1717686 (-)	810	Protein_1706	ABC transporter substrate-binding protein	-
AAIS09_RS08625 (AAIS09_08610)	amiF	1718303..1719229 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
AAIS09_RS08630 (AAIS09_08615)	amiE	1719240..1720307 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
AAIS09_RS08635 (AAIS09_08620)	amiD	1720316..1721242 (-)	927	WP_000103697.1	oligopeptide ABC transporter permease OppC	Regulator
AAIS09_RS08640 (AAIS09_08625)	amiC	1721242..1722738 (-)	1497	WP_000759902.1	ABC transporter permease	Regulator
AAIS09_RS08645 (AAIS09_08630)	amiA3	1722805..1724784 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=993696 AAIS09_RS08630 WP_000159554.1 1719240..1720307(-) (amiE) [Streptococcus pneumoniae strain serotype 4]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=993696 AAIS09_RS08630 WP_000159554.1 1719240..1720307(-) (amiE) [Streptococcus pneumoniae strain serotype 4]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCGAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541