Detailed information NTG0993355

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: AAHT66_RS11495
• Genome accession: NZ_CP154441
• Coordinates: 2212538..2213152 (+)
• Length: 204 a.a.
• NCBI ID: WP_087990780.1
• Uniprot ID: -
• Organism: Bacillus inaquosorum strain XN303
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2207538..2218152

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAHT66_RS11460 (AAHT66_11460)	aroE	2208196..2209038 (+)	843	WP_202327125.1	shikimate dehydrogenase	-
AAHT66_RS11465 (AAHT66_11465)	yhbY	2209032..2209322 (+)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
AAHT66_RS11470 (AAHT66_11470)	-	2209334..2209903 (+)	570	WP_087990784.1	nicotinate-nucleotide adenylyltransferase	-
AAHT66_RS11475 (AAHT66_11475)	yqeK	2209893..2210453 (+)	561	WP_087990783.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
AAHT66_RS11480 (AAHT66_11480)	rsfS	2210471..2210827 (+)	357	WP_019258939.1	ribosome silencing factor	-
AAHT66_RS11485 (AAHT66_11485)	-	2210824..2211567 (+)	744	WP_087990782.1	class I SAM-dependent DNA methyltransferase	-
AAHT66_RS11490 (AAHT66_11490)	comER	2211633..2212454 (-)	822	WP_087990781.1	late competence protein ComER	-
AAHT66_RS11495 (AAHT66_11495)	comEA	2212538..2213152 (+)	615	WP_087990780.1	helix-hairpin-helix domain-containing protein	Machinery gene
AAHT66_RS11500 (AAHT66_11500)	-	2213219..2213788 (+)	570	WP_087990779.1	ComE operon protein 2	-
AAHT66_RS11505 (AAHT66_11505)	comEC	2213792..2216107 (+)	2316	WP_333516577.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAHT66_RS11510 (AAHT66_11510)	-	2216162..2216296 (-)	135	WP_003229983.1	YqzM family protein	-
AAHT66_RS11515 (AAHT66_11515)	-	2216337..2216486 (+)	150	WP_141113374.1	hypothetical protein	-
AAHT66_RS11520 (AAHT66_11520)	holA	2216526..2217569 (+)	1044	WP_333516576.1	DNA polymerase III subunit delta	-
AAHT66_RS11525 (AAHT66_11525)	rpsT	2217584..2217850 (-)	267	WP_087990776.1	30S ribosomal protein S20	-

Sequence

Protein

• Length: 204 a.a.
• Molecular weight: 21846.72 Da
• Isoelectric Point: 4.5996

>NTDB_id=993355 AAHT66_RS11495 WP_087990780.1 2212538..2213152(+) (comEA) [Bacillus inaquosorum strain XN303]
MNWLYLHKKAIILAASAAAFIAVIFVLASGENKEPVKQAVSTETENTEVKQEAVKDENDTIVIDIKGAVQHPGVYEMRTG
DRVSQAIEKAGGTGEQADEMQVNLAELLQDGIVVYIPKKGEETTMQQGFGGAVKSDGGKEAPVNINTATLEELQGISGVG
PSKAEAIIGYREENGRFQTIEELTKVSGIGEKSLEKIKSSITVK

Nucleotide

• Length: 615 bp

>NTDB_id=993355 AAHT66_RS11495 WP_087990780.1 2212538..2213152(+) (comEA) [Bacillus inaquosorum strain XN303]
ATGAATTGGTTGTATCTGCATAAAAAAGCAATCATTTTAGCGGCTTCTGCAGCTGCTTTCATAGCGGTTATTTTCGTTTT
GGCCAGCGGGGAAAACAAAGAGCCGGTGAAGCAGGCTGTATCAACTGAGACAGAAAATACGGAGGTAAAGCAGGAGGCGG
TAAAAGACGAGAACGATACCATTGTGATTGATATAAAGGGTGCTGTTCAGCATCCTGGCGTGTATGAAATGCGAACAGGG
GACAGAGTATCTCAGGCGATTGAGAAAGCGGGCGGGACCGGTGAACAAGCAGATGAAATGCAAGTGAATTTGGCGGAGCT
GCTGCAGGACGGGATAGTGGTGTACATCCCGAAAAAGGGAGAAGAGACAACAATGCAGCAAGGATTCGGAGGCGCTGTGA
AAAGCGATGGAGGGAAGGAAGCACCGGTAAATATCAATACAGCAACCTTAGAGGAATTACAAGGCATCTCAGGGGTGGGG
CCATCAAAGGCTGAAGCTATTATTGGATACCGGGAAGAAAACGGGCGTTTCCAGACAATTGAAGAGCTCACTAAAGTTTC
AGGAATCGGTGAGAAGTCGCTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (62-116)

• Helix-hairpin-helix motif (HHH_3) (140-202)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	84.878	100	0.853
comEA	Latilactobacillus sakei subsp. sakei 23K	32.627	100	0.377
comEA	Staphylococcus aureus MW2	36.019	100	0.373
comEA/celA/cilE	Streptococcus pneumoniae Rx1	50	72.549	0.363
comEA/celA/cilE	Streptococcus pneumoniae D39	50	72.549	0.363
comEA/celA/cilE	Streptococcus pneumoniae R6	50	72.549	0.363