Detailed information NTG0992870

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: TTHNP4_RS06205
• Genome accession: NZ_LR027517
• Coordinates: 1127269..1129479 (+)
• Length: 736 a.a.
• NCBI ID: WP_014630003.1
• Uniprot ID: -
• Organism: Thermus thermophilus isolate TTHNAR1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1122269..1134479

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TTHNP4_RS06170 (TTHN1_01244)	-	1122767..1123195 (-)	429	WP_124104834.1	hypothetical protein	-
TTHNP4_RS06175 (TTHN1_01245)	-	1123188..1123499 (-)	312	WP_060384649.1	DUF3234 domain-containing protein	-
TTHNP4_RS06180 (TTHN1_01246)	-	1123517..1124224 (+)	708	WP_124104835.1	TlyA family RNA methyltransferase	-
TTHNP4_RS06185 (TTHN1_01247)	-	1124211..1125206 (-)	996	WP_124104836.1	aspartate-semialdehyde dehydrogenase	-
TTHNP4_RS06190 (TTHN1_01248)	-	1125203..1125439 (-)	237	WP_011172631.1	hypothetical protein	-
TTHNP4_RS06200 (TTHN1_01249)	-	1125620..1127140 (-)	1521	WP_124104838.1	glycine--tRNA ligase	-
TTHNP4_RS06205 (TTHN1_01250)	clpC	1127269..1129479 (+)	2211	WP_014630003.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
TTHNP4_RS06210 (TTHN1_01251)	radA	1129490..1130761 (+)	1272	WP_124104839.1	DNA repair protein RadA	Machinery gene
TTHNP4_RS06215 (TTHN1_01252)	-	1130758..1131768 (+)	1011	WP_124104840.1	PIN/TRAM domain-containing protein	-
TTHNP4_RS06220 (TTHN1_01253)	-	1131762..1132796 (-)	1035	WP_124104841.1	bis-aminopropyl spermidine synthase family protein	-
TTHNP4_RS06225 (TTHN1_01254)	sucC	1132841..1134016 (+)	1176	WP_124104842.1	ADP-forming succinate--CoA ligase subunit beta	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 81410.33 Da
• Isoelectric Point: 5.4038

>NTDB_id=992870 TTHNP4_RS06205 WP_014630003.1 1127269..1129479(+) (clpC) [Thermus thermophilus isolate TTHNAR1]
MNRYDDRARLVFHYAREEGSRLGHSMIGPEHLLLGLMREGGTAARILQEYGASLEAMRRMVEELVGRGEGGRTGEPPAIT
PRARRVMELASAEARNMGSPVIGTEHILLGIIREGDGIAYRILSHFAKDVDAIRWRVLAMAEGREREKPVNTPFLDEYGR
DLTKEAREGKLDPVIGRQEEINRVIQILARRTKNNPVLIGDPGVGKTAIVEGLAQAIVEGRVPPILKGARVVAIDLAGVV
AGTKYRGEFEERLRQIIEELKNAKVIAFIDELHTLIGAGGAEGTLDAANILKPALARGEIQVIGATTTGEYHRYIEKDAA
LERRFQPVIVLEPSPEETLEILKGLRPRYEAHHGVIIPDEILELAVKIGIRSLPGRNFPDKAIDLIDEAASRVRLNASLG
LPVAEEEDGTPIVTREDVEAVVDSWGGVYVDDKDDEKLMRLEEELRKRVVGQEEAIRALANALRRARVGLGGRTRVAASF
LFVGQSGVGKTQLAKALAEVLFGSERALIRFDMSEFQEPHSISKLIGAPPGYVGYEQGGRLTEAVRRQPFSVVLLDEIEK
AHPDIYNTFLQVLDEGRLTDGMGRTVDFRRVILIMTSNTGYNVGPAIGFTSKEVDTESPLKALFTPEFLDRLDEVIRFRP
LTEEELVRVAEMMLEDIRKELQARDVQVSFAPEVARFLVDQAPKTGSARALRSVLRERIEDPLAVALLRKPTGRIHVSVE
GGQVAFHEVEGEELLV

Nucleotide

• Length: 2211 bp

>NTDB_id=992870 TTHNP4_RS06205 WP_014630003.1 1127269..1129479(+) (clpC) [Thermus thermophilus isolate TTHNAR1]
ATGAACCGATACGACGACCGCGCCAGGCTGGTCTTTCACTACGCAAGAGAGGAGGGGAGCCGCTTAGGCCACTCCATGAT
CGGCCCAGAGCACCTCCTCCTGGGCCTGATGCGCGAGGGGGGAACGGCGGCCCGTATCCTCCAGGAGTACGGGGCGAGCC
TCGAGGCCATGCGCCGCATGGTGGAGGAGCTGGTGGGCCGGGGGGAGGGCGGGCGCACCGGGGAGCCCCCCGCCATCACC
CCGAGGGCAAGGCGGGTTATGGAGCTCGCCAGCGCCGAGGCCCGCAACATGGGCTCCCCCGTCATCGGCACGGAGCACAT
CCTCCTCGGCATCATCCGGGAGGGGGACGGGATCGCCTACCGCATCCTCAGCCACTTCGCCAAGGACGTGGACGCCATCC
GCTGGAGGGTCCTGGCCATGGCCGAGGGCCGCGAGCGGGAAAAGCCCGTGAACACCCCCTTCCTGGACGAGTACGGCCGC
GACCTCACCAAGGAAGCCCGGGAAGGGAAGCTGGACCCGGTGATCGGCCGCCAGGAGGAGATCAACCGGGTGATCCAGAT
CCTCGCCCGGCGTACCAAGAATAACCCCGTCCTCATCGGTGACCCCGGGGTGGGCAAGACGGCCATCGTGGAAGGCCTGG
CCCAGGCCATCGTGGAGGGCCGGGTCCCCCCCATCCTCAAGGGGGCCCGGGTGGTGGCCATTGACCTCGCCGGGGTGGTG
GCGGGGACCAAGTACCGGGGCGAGTTTGAGGAGCGCCTGCGGCAGATCATTGAGGAGCTCAAGAACGCCAAGGTCATCGC
CTTCATTGACGAGCTCCACACCCTGATCGGGGCGGGCGGGGCCGAGGGCACCCTGGACGCCGCCAACATCCTCAAGCCCG
CCCTGGCCCGCGGGGAGATCCAGGTGATCGGGGCCACCACCACCGGGGAGTACCACCGCTACATAGAGAAGGACGCGGCC
CTGGAGCGGCGCTTCCAGCCGGTGATCGTCCTCGAGCCCTCCCCCGAGGAAACCCTGGAGATCCTCAAGGGCCTCCGCCC
CCGGTACGAAGCCCACCACGGGGTGATCATCCCCGACGAAATCCTGGAGCTTGCGGTGAAGATCGGGATCCGCTCGCTTC
CCGGGCGCAACTTCCCCGACAAGGCCATTGACCTCATTGACGAGGCGGCCTCGAGGGTGCGCCTGAACGCCTCCTTGGGC
CTCCCCGTGGCGGAGGAAGAGGACGGCACCCCCATCGTCACCCGGGAGGACGTGGAGGCGGTGGTGGACTCCTGGGGCGG
GGTCTACGTGGACGACAAGGACGACGAGAAGCTCATGCGCCTGGAGGAGGAGCTCAGGAAGCGGGTGGTGGGCCAGGAGG
AGGCCATCCGCGCCCTAGCGAACGCCCTCCGCCGGGCCCGGGTGGGGCTTGGGGGAAGGACCCGGGTGGCGGCGAGCTTC
CTCTTCGTGGGGCAAAGCGGCGTGGGCAAGACCCAGCTCGCCAAGGCCCTGGCCGAGGTCCTCTTCGGCTCGGAGAGGGC
CCTCATCCGCTTTGACATGTCCGAGTTCCAGGAGCCCCACTCCATCTCCAAGCTCATCGGAGCCCCGCCGGGCTATGTGG
GCTACGAGCAGGGGGGCCGCCTCACCGAGGCCGTGCGCCGCCAGCCCTTCAGCGTGGTCCTCCTGGACGAGATTGAGAAG
GCCCACCCCGACATCTACAACACCTTCCTCCAGGTGCTGGACGAGGGCCGCCTCACGGACGGCATGGGCCGCACCGTGGA
CTTCCGCCGGGTCATCCTCATCATGACCTCCAACACCGGCTACAACGTGGGCCCCGCCATCGGCTTCACCTCCAAGGAGG
TGGACACGGAGTCCCCCCTGAAGGCCCTCTTCACCCCCGAGTTTCTGGACCGGCTGGACGAGGTCATCCGCTTCCGGCCC
CTCACGGAGGAGGAGCTGGTGCGGGTGGCCGAGATGATGCTGGAGGACATCCGCAAGGAGCTCCAGGCCCGGGACGTCCA
GGTGAGCTTCGCCCCCGAGGTGGCCCGCTTCTTGGTGGACCAGGCCCCCAAGACGGGGAGCGCCCGCGCCCTGCGGAGCG
TCCTAAGGGAGCGCATAGAGGACCCCTTGGCCGTCGCCCTCCTGCGGAAGCCCACGGGCCGGATCCACGTGAGCGTGGAG
GGAGGCCAGGTGGCCTTCCACGAGGTGGAGGGGGAGGAGCTCCTCGTCTAG

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (334-397)

• AAA domain (Cdc48 subfamily) (AAA_2) (478-635)

• ATPase family associated with various cellular activities (AAA) (AAA) (197-330)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (641-711)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-66)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (90-140)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48.02	100	0.527
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.588	100	0.461
clpC	Streptococcus pneumoniae D39	41.762	100	0.444
clpC	Streptococcus pneumoniae Rx1	41.762	100	0.444
clpC	Streptococcus pneumoniae TIGR4	41.379	100	0.44
clpC	Streptococcus thermophilus LMD-9	39.698	100	0.429
clpC	Streptococcus thermophilus LMG 18311	39.447	100	0.427
clpC	Streptococcus mutans UA159	39.544	100	0.424
clpE	Streptococcus mutans UA159	48.609	83.016	0.404
clpE	Streptococcus pneumoniae R6	47.386	83.152	0.394
clpE	Streptococcus pneumoniae Rx1	47.386	83.152	0.394
clpE	Streptococcus pneumoniae D39	47.386	83.152	0.394
clpC	Lactococcus lactis subsp. cremoris KW2	47.463	83.016	0.394
clpE	Streptococcus pneumoniae TIGR4	47.222	83.152	0.393
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	39.017	94.022	0.367