Detailed information NTG0992011

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: A66_RS08955
• Genome accession: NZ_LN847353
• Coordinates: 1702888..1703787 (-)
• Length: 299 a.a.
• NCBI ID: WP_050204738.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain A66
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1697888..1708787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A66_RS08935 (A66_01779)	rsmA	1698112..1698984 (-)	873	WP_001216878.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
A66_RS12645	-	1699235..1699528 (-)	294	Protein_1731	hypothetical protein	-
A66_RS08940 (A66_01782)	-	1699521..1700162 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
A66_RS08945 (A66_01783)	-	1700164..1702194 (-)	2031	WP_053039762.1	bacteriocin-associated integral membrane family protein	-
A66_RS08950 (A66_01784)	-	1702271..1702567 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
A66_RS08955 (A66_01785)	comR	1702888..1703787 (-)	900	WP_050204738.1	helix-turn-helix transcriptional regulator	Regulator
A66_RS08960 (A66_01786)	rnmV	1703859..1704419 (-)	561	WP_000660009.1	ribonuclease M5	-
A66_RS08965 (A66_01787)	-	1704419..1705192 (-)	774	WP_000575634.1	TatD family hydrolase	-
A66_RS08970 (A66_01788)	-	1705497..1706468 (-)	972	Protein_1738	DUF1542 domain-containing protein	-
A66_RS08975 (A66_01789)	rpmH	1706674..1706808 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
A66_RS08980 (A66_01790)	-	1706953..1708167 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
A66_RS08985 (A66_01791)	-	1708323..1708616 (-)	294	WP_000977374.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35399.12 Da
• Isoelectric Point: 4.7732

>NTDB_id=992011 A66_RS08955 WP_050204738.1 1702888..1703787(-) (comR) [Streptococcus pneumoniae strain A66]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=992011 A66_RS08955 WP_050204738.1 1702888..1703787(-) (comR) [Streptococcus pneumoniae strain A66]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	38.095	98.328	0.375
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.577	99.666	0.365