Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SP4011_RS11245 Genome accession   NZ_AP026968
Coordinates   2294787..2296085 (-) Length   432 a.a.
NCBI ID   WP_338619355.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2289787..2301085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS11225 (SP4011_21710) rplI 2290942..2291394 (-) 453 WP_000864214.1 50S ribosomal protein L9 -
  SP4011_RS11230 (SP4011_21720) - 2291391..2293364 (-) 1974 WP_338619354.1 DHH family phosphoesterase -
  SP4011_RS11235 (SP4011_21730) hpf 2293500..2294048 (-) 549 WP_050142688.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SP4011_RS11240 (SP4011_21740) comFC/cflB 2294128..2294790 (-) 663 WP_262081990.1 ComF family protein Machinery gene
  SP4011_RS11245 (SP4011_21750) comFA/cflA 2294787..2296085 (-) 1299 WP_338619355.1 DEAD/DEAH box helicase Machinery gene
  SP4011_RS11250 (SP4011_21760) - 2296142..2296777 (+) 636 WP_338619356.1 YigZ family protein -
  SP4011_RS11255 (SP4011_21770) cysK 2297062..2297988 (+) 927 WP_338619357.1 cysteine synthase A -
  SP4011_RS11260 (SP4011_21780) tsf 2298110..2299150 (-) 1041 WP_173234333.1 translation elongation factor Ts -
  SP4011_RS11265 (SP4011_21790) rpsB 2299230..2300009 (-) 780 WP_000268466.1 30S ribosomal protein S2 -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49492.29 Da        Isoelectric Point: 7.6115

>NTDB_id=99149 SP4011_RS11245 WP_338619355.1 2294787..2296085(-) (comFA/cflA) [Streptococcus parapneumoniae strain SP4011]
MKVNPNYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCNSAILDEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLIQAVDKQEPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
LQDDFACEIALLHGESKPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKENGLRIFLTATST
DELDRKVRLGELKRLSLPRRFHGNPLIIPKPVWLSDFNHCLEKSRLSPKLKSYIEKQRKTAYPLLIFASEIKQGEQLKEI
LQEQFPNEKIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHHLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNDSIKKTIKEIQMMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=99149 SP4011_RS11245 WP_338619355.1 2294787..2296085(-) (comFA/cflA) [Streptococcus parapneumoniae strain SP4011]
ATGAAAGTAAATCCAAATTATCTCGGTCGTTTGTTTACGGAGAATGAATTAACAGAAGAAGAACGTCAGTTGGCGGAGAA
ACTTCCAGCAATGAGAAAGGAGAAAGGGAAACTTTTCTGTCAACGTTGTAATAGTGCTATTTTAGATGAATGGTATTTGC
CCATCGGTGCTTACTATTGTAGGGAGTGTTTACTGATGAAGCGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCACAG
GAGGATTTTCCGAAGCAAGATGTTCTTAAATGGCGTGGTCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGAT
TCAAGCAGTAGACAAGCAGGAGCCAACCTTAGTTCATGCAGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTTG
TGGCTAAAGTAATCAATGCGGGTGGTGCAGTGTGTTTGGCCAGTCCTCGCATAGATGTTTGTTTGGAGCTATACAAACGC
CTGCAAGATGATTTTGCTTGCGAGATAGCCCTCCTACATGGAGAATCAAAGCCGTATTTTCGAACACCACTAGTTGTTGC
GACGACCCATCAGTTATTGAAATTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCTTTTCCTTATGTTG
ACAATCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGGAGAATGGGTTGAGAATCTTTTTAACAGCGACTTCGACA
GATGAGTTAGATAGGAAAGTCCGTTTAGGAGAACTAAAAAGGTTGAGCTTACCTAGACGATTCCATGGAAATCCGTTGAT
TATTCCTAAACCAGTTTGGTTATCCGATTTTAATCACTGTTTAGAGAAAAGTCGTTTGTCACCAAAGTTAAAGTCCTATA
TTGAGAAACAGCGAAAGACAGCTTATCCGTTACTCATTTTTGCATCAGAAATTAAACAAGGGGAGCAGTTAAAAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGTTTTGTATCTTCTGTAACAGAGGATAGATTAGAGCAGGTACAAGCATT
TCGAGATGGGGAGCTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACATTCCCTTGTGTGGACGTTTTCG
TAGTAGAGGCCAATCATCATTTGTTTACCAAGTCTAGTTTGATTCAAATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTACTTTTCTTCCATGATGGGTTAAATGATTCAATCAAGAAGACGATTAAGGAAATTCAGATGATGAA
TAAGGAGGCTGGTCTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(293-396)

Type III restriction enzyme, res subunit (ResIII)

(94-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

94.907

100

0.949
  comFA/cflA Streptococcus mitis SK321

94.213

100

0.942
  comFA/cflA Streptococcus pneumoniae Rx1

94.213

100

0.942
  comFA/cflA Streptococcus pneumoniae D39

94.213

100

0.942
  comFA/cflA Streptococcus pneumoniae R6

94.213

100

0.942
  comFA/cflA Streptococcus pneumoniae TIGR4

93.981

100

0.94
  comFA Lactococcus lactis subsp. cremoris KW2

50.117

99.306

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

38.337

100

0.384

Multiple sequence alignment