Detailed information NTG0990646

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: V4T04_RS04165
• Genome accession: NZ_JAZICS010000003
• Coordinates: 47454..48824 (-)
• Length: 456 a.a.
• NCBI ID: WP_003130363.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain DGCC12653
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 42454..53824

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V4T04_RS04150	-	43624..45057 (-)	1434	WP_017864852.1	6-phospho-beta-glucosidase	-
V4T04_RS04155	yidD	45181..45447 (-)	267	WP_012898265.1	membrane protein insertion efficiency factor YidD	-
V4T04_RS04160	-	45564..47306 (-)	1743	WP_010906088.1	1-deoxy-D-xylulose-5-phosphate synthase	-
V4T04_RS04165	ciaH	47454..48824 (-)	1371	WP_003130363.1	sensor histidine kinase	Regulator
V4T04_RS04170	ciaR	48917..49585 (-)	669	WP_021722129.1	response regulator transcription factor	Regulator
V4T04_RS04175	-	49763..50737 (-)	975	WP_003130365.1	LacI family DNA-binding transcriptional regulator	-
V4T04_RS04180	-	50890..53145 (-)	2256	WP_033899078.1	glycoside hydrolase family 65 protein	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 51300.85 Da
• Isoelectric Point: 9.4537

>NTDB_id=990646 V4T04_RS04165 WP_003130363.1 47454..48824(-) (ciaH) [Lactococcus lactis subsp. lactis strain DGCC12653]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTNFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide

• Length: 1371 bp

>NTDB_id=990646 V4T04_RS04165 WP_003130363.1 47454..48824(-) (ciaH) [Lactococcus lactis subsp. lactis strain DGCC12653]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAACTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAAACTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAATACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATTAAACAATTGCTAACCATCTTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (333-442)

• His Kinase A (phospho-acceptor) domain (HisKA) (223-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	48.837	94.298	0.461
ciaH	Streptococcus pneumoniae Rx1	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae D39	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae R6	44.321	98.465	0.436
ciaH	Streptococcus pneumoniae TIGR4	44.321	98.465	0.436