Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GBSCOH1_RS09825 Genome accession   NZ_HG939456
Coordinates   1968552..1970525 (-) Length   657 a.a.
NCBI ID   WP_000034615.1    Uniprot ID   -
Organism   Streptococcus agalactiae COH1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1963552..1975525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBSCOH1_RS09800 (GBSCOH1_1894) recA 1963561..1964700 (-) 1140 WP_001085741.1 recombinase RecA -
  GBSCOH1_RS09805 (GBSCOH1_1895) cinA 1964774..1966033 (-) 1260 WP_001200982.1 competence/damage-inducible protein A Machinery gene
  GBSCOH1_RS09810 (GBSCOH1_1896) - 1966122..1966673 (-) 552 WP_000817340.1 DNA-3-methyladenine glycosylase I -
  GBSCOH1_RS09815 (GBSCOH1_1897) ruvA 1966696..1967286 (-) 591 WP_000272489.1 Holliday junction branch migration protein RuvA Machinery gene
  GBSCOH1_RS09820 (GBSCOH1_1898) - 1967288..1968520 (-) 1233 WP_000657474.1 MDR family MFS transporter -
  GBSCOH1_RS09825 (GBSCOH1_1899) hexB 1968552..1970525 (-) 1974 WP_000034615.1 DNA mismatch repair endonuclease MutL Machinery gene
  GBSCOH1_RS09830 (GBSCOH1_1900) - 1970751..1970954 (+) 204 WP_000191849.1 cold-shock protein -
  GBSCOH1_RS09835 (GBSCOH1_1901) hexA 1971011..1973587 (-) 2577 WP_001118373.1 DNA mismatch repair protein MutS Machinery gene
  GBSCOH1_RS09840 (GBSCOH1_1902) argR 1973644..1974081 (-) 438 WP_001033152.1 arginine repressor -

Sequence

Protein


Download         Length: 657 a.a.        Molecular weight: 73808.90 Da        Isoelectric Point: 5.3704

>NTDB_id=989909 GBSCOH1_RS09825 WP_000034615.1 1968552..1970525(-) (hexB) [Streptococcus agalactiae COH1]
MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKY
MKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLP
ELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISS
AISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQSGLYYDRTKNDFFIDADTVSEPIANFTNLDKSDGSVDNDVK
NSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIID
QHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEEVE
SGVYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKM
FKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1974 bp        

>NTDB_id=989909 GBSCOH1_RS09825 WP_000034615.1 1968552..1970525(-) (hexB) [Streptococcus agalactiae COH1]
TTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGGCCTAGTAGCGT
CGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTCTTAAAA
AGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCCGTTCTCAGTTTACGACGTCACGCTACATCCAAA
ATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCTCTACCATCAATCGCTTCGATTAG
TTTAATGACAATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTGAAAAAC
AGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAATACGCCTGCCAGATTGAAATAC
ATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGTTGCTTT
TACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTATTTATG
GTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGTTTGCCT
GAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGGTCGTTACATTAAAAATTTTCTTTTAAACCGCTC
AATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATCCTTATC
TAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATAAGCTCA
GCAATTTCTGAGAGTCTGAAACAATATGATTTGATTCCGGATGCTTTAGAGAATTTAGCGAAAACTAGTACCCGAAGTGT
AGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGTCTGGTTTGTATTACGATAGGACTAAAAATGACTTTTTTATAG
ATGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGATGTAAAA
AACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAACTTCAT
TCATTCTCAGGACTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTTCGACTT
TTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATTATTGAT
CAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCAACAATT
GTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAGATGTTG
GTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAGGTAGAG
TCTGGCGTTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTATCAGTGAAAAAATATCGCGCAGAGTTGGCTAT
TATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATCAGTTAG
CGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAGAAAATG
TTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(458-601)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.044

100

0.693