Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   HMPREF9319_RS09565 Genome accession   NZ_GL397128
Coordinates   1989966..1991909 (-) Length   647 a.a.
NCBI ID   WP_003066924.1    Uniprot ID   E0PGF7
Organism   Streptococcus equinus ATCC 700338     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1984966..1996909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS09540 (HMPREF9319_1996) - 1985967..1986920 (-) 954 WP_003066905.1 MFS transporter -
  HMPREF9319_RS11285 (HMPREF9319_1997) - 1987367..1987576 (-) 210 WP_003066908.1 hypothetical protein -
  HMPREF9319_RS11290 (HMPREF9319_1998) - 1987534..1987815 (-) 282 WP_003066911.1 hypothetical protein -
  HMPREF9319_RS11295 (HMPREF9319_1999) - 1987885..1988055 (-) 171 WP_231729898.1 hypothetical protein -
  HMPREF9319_RS11300 (HMPREF9319_2000) - 1988116..1988292 (-) 177 WP_003066916.1 hypothetical protein -
  HMPREF9319_RS09555 (HMPREF9319_2001) - 1988440..1989291 (+) 852 WP_003066919.1 helix-turn-helix domain-containing protein -
  HMPREF9319_RS09560 (HMPREF9319_2002) ruvA 1989371..1989964 (-) 594 WP_003066922.1 Holliday junction branch migration protein RuvA Machinery gene
  HMPREF9319_RS09565 (HMPREF9319_2003) hexB 1989966..1991909 (-) 1944 WP_003066924.1 DNA mismatch repair endonuclease MutL Machinery gene
  HMPREF9319_RS09570 (HMPREF9319_2004) hexA 1992025..1994595 (-) 2571 WP_003066925.1 DNA mismatch repair protein MutS Machinery gene
  HMPREF9319_RS09575 (HMPREF9319_2005) - 1994582..1994938 (-) 357 WP_003066927.1 YlbF family regulator -
  HMPREF9319_RS09580 (HMPREF9319_2006) argR 1994935..1995372 (-) 438 WP_003066930.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73287.38 Da        Isoelectric Point: 5.0956

>NTDB_id=989453 HMPREF9319_RS09565 WP_003066924.1 1989966..1991909(-) (hexB) [Streptococcus equinus ATCC 700338]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEEAGLKKIQVTDNGEGIAQDDVALSLHRHATSK
IKNQADLFRIRTLGFRGEAIPSIASISHFTVKTATADENYGTLLVAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEVAFSLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMSLISS
AIAESLREQDLIPDALENLAKSSTRGLPKPEQTSLPLKQTDLYYDKERRDFFVKSDTVEEQPVQLFNEVDNSVKEVDKQQ
TSVKYAQRSEVDNQDDEHDNLDFKNKTKINKMIESLDNEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKY
EYYREKIGDVDSSLQQLLMPYLFEFSGADFIKLQEKMELLNQVGIYLEPYGNNTFILREHPIWMKEEEIETAVYEMCDML
LLTNEVSVKKYRAELAIMMSCKRSIKANHILDDYSARHLLVQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=989453 HMPREF9319_RS09565 WP_003066924.1 1989966..1991909(-) (hexB) [Streptococcus equinus ATCC 700338]
ATGAGTAAAATTATTGAGTTGCCAGAGGTTTTGGCTAACCAAATTGCAGCGGGTGAAGTTATTGAACGACCAGCTAGCGT
TGTCAAAGAATTGGTGGAAAATTCGATTGATGCAGGGAGCAGCCAAATCACCATTGAAATTGAAGAAGCTGGTTTAAAGA
AAATTCAAGTGACAGATAATGGCGAAGGAATTGCTCAAGATGATGTTGCATTAAGTTTGCACCGCCATGCCACAAGTAAA
ATTAAAAATCAAGCTGACCTTTTCCGTATTAGGACGTTAGGTTTTCGTGGTGAAGCGATACCGTCAATTGCCTCCATTAG
TCATTTTACAGTCAAAACAGCAACGGCAGATGAAAATTATGGAACATTGCTAGTAGCCAAAGGTGGTGAAATCGAAAAAC
AAGAACCGATTTCTACACCCGTTGGAACCAAAATTACGGTTGAAAATCTCTTTTATAATACGCCAGCACGTCTTAAATAC
ATGAAAAGTCTCCAATCCGAATTAGCTCATATTGTTGATGTGGTGAATCGTTTGAGTTTGGCGCACCCAGAGGTAGCTTT
TAGCTTGATTAATGATGGTCGTCAAATGACAACAACATCTGGTACTGGTGATTTGCGACAAGCAATTGCTGGTATTTATG
GGCTTAATACGGCTAAAAAAATGATTGAGATTTCGAATGCTGACCTCGATTTTGAAGTGTCTGGTTACATTAGTCTGCCA
GAATTGACACGAGCGAACCGAAACTATATTACGATTTTGATTAACGGTCGTTATATTAAAAACTTTTTGCTCAATCGTGC
GATTTTGGACGGTTATGGTTCAAAATTGATGGTGGGACGTTTTCCGATTGCTGTTATCGACATTCAAATCGACCCTTATT
TAGCTGATGTCAATGTTCACCCAACGAAGCAAGAAGTTCGTATTTCAAAGGAAAAAGAATTAATGAGCTTAATCAGCTCT
GCTATTGCAGAGAGTCTGCGTGAGCAAGATTTGATACCTGATGCTCTAGAAAATCTGGCGAAATCAAGCACACGTGGGCT
TCCGAAACCAGAGCAAACGAGCTTGCCGTTGAAACAAACAGACCTTTATTATGATAAAGAACGTCGTGATTTCTTTGTTA
AGTCAGATACGGTTGAAGAGCAACCAGTACAGTTATTCAATGAGGTTGACAACTCTGTCAAGGAAGTTGACAAGCAACAA
ACATCAGTGAAATATGCGCAGCGTTCCGAAGTAGATAATCAAGATGATGAACATGATAATCTCGATTTTAAAAACAAGAC
AAAAATCAATAAGATGATTGAAAGTCTTGATAATGAGGAGTCATCAACTTTCCCAGAATTAGATTATTTCGGACAAATGC
ACGGAACGTATCTTTTTGCACAGGGAAATGGTGGGCTTTATATCATTGACCAACACGCTGCTCAAGAACGTGTTAAATAT
GAATATTATCGTGAGAAAATCGGCGACGTTGACAGCTCTTTACAGCAGCTTCTCATGCCATACCTTTTTGAGTTTTCTGG
AGCTGATTTTATTAAGTTGCAAGAAAAAATGGAGCTGTTAAATCAAGTTGGTATTTATCTAGAACCATATGGAAACAACA
CTTTTATTCTCCGTGAACACCCAATTTGGATGAAAGAAGAGGAAATTGAGACGGCTGTTTATGAGATGTGTGATATGCTG
TTGTTGACAAATGAAGTATCGGTGAAGAAATATCGTGCAGAATTGGCAATCATGATGTCATGCAAACGCTCAATCAAAGC
GAATCACATTCTTGATGATTATTCCGCCCGACATCTTTTGGTTCAGTTATCACAATGTAAGAATCCTTATAACTGTCCAC
ATGGACGTCCAGTTCTTGTCAACTTTACCAAAGCTGACATGGAAAAAATGTTCCGCCGTATTCAAGAAAATCACACAAGT
TTAAGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-119)

MutL C terminal dimerisation domain (MutL_C)

(449-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PGF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.904

100

0.716