Detailed information NTG0989361

Bioinformatically predicted

Overview

• Name: comGE
• Type: Machinery gene
• Locus tag: HMPREF9319_RS00405
• Genome accession: NZ_GL397128
• Coordinates: 71713..72006 (+)
• Length: 97 a.a.
• NCBI ID: WP_080543606.1
• Uniprot ID: -
• Organism: Streptococcus equinus ATCC 700338
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 66713..77006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9319_RS00380 (HMPREF9319_0069)	-	68710..69072 (+)	363	WP_003062916.1	DUF1033 family protein	-
HMPREF9319_RS00385 (HMPREF9319_0070)	comGA	69143..70084 (+)	942	WP_003062917.1	competence type IV pilus ATPase ComGA	Machinery gene
HMPREF9319_RS00390 (HMPREF9319_0071)	comGB	70008..71051 (+)	1044	WP_003062919.1	competence type IV pilus assembly protein ComGB	Machinery gene
HMPREF9319_RS00395 (HMPREF9319_0072)	comGC	71051..71344 (+)	294	WP_003062921.1	competence type IV pilus major pilin ComGC	Machinery gene
HMPREF9319_RS00400 (HMPREF9319_0073)	comGD	71328..71759 (+)	432	WP_003062922.1	competence type IV pilus minor pilin ComGD	Machinery gene
HMPREF9319_RS00405 (HMPREF9319_0074)	comGE	71713..72006 (+)	294	WP_080543606.1	competence type IV pilus minor pilin ComGE	Machinery gene
HMPREF9319_RS00410 (HMPREF9319_0075)	comGF	71990..72427 (+)	438	WP_041974065.1	competence type IV pilus minor pilin ComGF	Machinery gene
HMPREF9319_RS00415 (HMPREF9319_0076)	comGG	72399..72731 (+)	333	WP_003062925.1	competence type IV pilus minor pilin ComGG	Machinery gene
HMPREF9319_RS00420 (HMPREF9319_0077)	comGH	72786..73757 (+)	972	WP_003062926.1	class I SAM-dependent methyltransferase	Machinery gene
HMPREF9319_RS00425 (HMPREF9319_0078)	-	73795..74994 (+)	1200	WP_003062927.1	acetate kinase	-
HMPREF9319_RS00430 (HMPREF9319_0079)	-	75155..75355 (+)	201	WP_013851401.1	helix-turn-helix transcriptional regulator	-
HMPREF9319_RS00435 (HMPREF9319_0080)	-	75365..75574 (+)	210	WP_003062929.1	hypothetical protein	-
HMPREF9319_RS00440 (HMPREF9319_0081)	-	75587..76039 (+)	453	WP_003062930.1	hypothetical protein	-
HMPREF9319_RS00445 (HMPREF9319_0082)	-	76051..76689 (+)	639	WP_003062931.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 97 a.a.
• Molecular weight: 11069.10 Da
• Isoelectric Point: 8.4757

>NTDB_id=989361 HMPREF9319_RS00405 WP_080543606.1 71713..72006(+) (comGE) [Streptococcus equinus ATCC 700338]
MVNIKRQKLKAYILLESLIALGLLAMITSIVLGEIDKNRQFMQESLRQQEVLNVATMAVQTGQNHLKMNGIEVEIIKKDG
EVYVYEAKTEILHVKKD

Nucleotide

• Length: 294 bp

>NTDB_id=989361 HMPREF9319_RS00405 WP_080543606.1 71713..72006(+) (comGE) [Streptococcus equinus ATCC 700338]
GTGGTAAATATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAAAGCTTGATAGCACTAGGATTGTTAGCGATGAT
TACGAGTATTGTTTTAGGGGAAATTGATAAAAATAGGCAGTTTATGCAAGAAAGTTTACGGCAGCAGGAAGTTCTTAATG
TGGCAACAATGGCTGTGCAAACAGGGCAAAATCATTTGAAGATGAATGGTATTGAGGTTGAGATTATCAAAAAAGATGGA
GAGGTCTATGTTTATGAGGCGAAAACGGAAATATTACATGTTAAAAAAGACTAG

Domains

Predicted by InterProScan.

• Type II secretory pathway pseudopilin (ComGE) (13-94)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE	Streptococcus mutans UA140	46.875	98.969	0.464
comGE	Streptococcus mutans UA159	46.875	98.969	0.464
comGE/cglE	Streptococcus mitis SK321	40.426	96.907	0.392
comGE/cglE	Streptococcus pneumoniae Rx1	40.426	96.907	0.392
comGE/cglE	Streptococcus pneumoniae D39	40.426	96.907	0.392
comGE/cglE	Streptococcus pneumoniae R6	40.426	96.907	0.392
comGE/cglE	Streptococcus pneumoniae TIGR4	40.426	96.907	0.392
comGE/cglE	Streptococcus mitis NCTC 12261	39.362	96.907	0.381