Detailed information NTG0098921

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8570_RS09520
• Genome accession: NZ_AP026932
• Coordinates: 1875418..1876428 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900701549
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1870418..1881428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8570_RS09500 (PC1528_18870)	-	1871719..1872012 (-)	294	WP_000977365.1	hypothetical protein	-
R8570_RS09505 (PC1528_18880)	-	1872174..1872626 (+)	453	WP_000079148.1	universal stress protein	-
R8570_RS09510 (PC1528_18890)	-	1872661..1874049 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
R8570_RS09515 (PC1528_18900)	-	1874115..1875077 (+)	963	WP_001124777.1	asparaginase	-
R8570_RS09520 (PC1528_18910)	ccpA	1875418..1876428 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8570_RS09525 (PC1528_18920)	-	1876852..1877451 (-)	600	WP_000866698.1	response regulator transcription factor	-
R8570_RS09530 (PC1528_18930)	-	1877452..1878549 (-)	1098	WP_000893537.1	sensor histidine kinase	-
R8570_RS09535 (PC1528_18940)	-	1878549..1879286 (-)	738	WP_001809843.1	ABC transporter permease	-
R8570_RS09540 (PC1528_18950)	-	1879288..1880172 (-)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
R8570_RS09545 (PC1528_18960)	-	1880159..1880353 (-)	195	WP_000820187.1	hypothetical protein	-
R8570_RS09550	-	1880350..1880556 (-)	207	Protein_1869	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=98921 R8570_RS09520 WP_000990607.1 1875418..1876428(-) (ccpA) [Streptococcus pneumoniae strain PZ900701549]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=98921 R8570_RS09520 WP_000990607.1 1875418..1876428(-) (ccpA) [Streptococcus pneumoniae strain PZ900701549]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568