Detailed information NTG0988949

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ACNR93_RS08930
• Genome accession: NZ_CP184736
• Coordinates: 1818509..1821079 (-)
• Length: 856 a.a.
• NCBI ID: WP_420543623.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NM-2-29
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1813509..1826079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNR93_RS08910 (ACNR93_08910)	-	1813946..1815148 (-)	1203	WP_420543621.1	MFS transporter	-
ACNR93_RS08915 (ACNR93_08915)	-	1815271..1815828 (-)	558	WP_198362632.1	DNA-3-methyladenine glycosylase I	-
ACNR93_RS08920 (ACNR93_08920)	ruvA	1815858..1816451 (-)	594	WP_024344431.1	Holliday junction branch migration protein RuvA	Machinery gene
ACNR93_RS08925 (ACNR93_08925)	hexB	1816452..1818395 (-)	1944	WP_420543622.1	DNA mismatch repair endonuclease MutL	Machinery gene
ACNR93_RS08930 (ACNR93_08930)	hexA	1818509..1821079 (-)	2571	WP_420543623.1	DNA mismatch repair protein MutS	Machinery gene
ACNR93_RS08935 (ACNR93_08935)	-	1821066..1821419 (-)	354	WP_027968295.1	YlbF family regulator	-
ACNR93_RS08940 (ACNR93_08940)	argR	1821416..1821853 (-)	438	WP_021143308.1	arginine repressor	-
ACNR93_RS08945 (ACNR93_08945)	argS	1822043..1823734 (+)	1692	WP_420543624.1	arginine--tRNA ligase	-
ACNR93_RS08950 (ACNR93_08950)	-	1823879..1825303 (-)	1425	Protein_1697	PTS transporter subunit EIIC	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96018.26 Da
• Isoelectric Point: 4.8397

>NTDB_id=988949 ACNR93_RS08930 WP_420543623.1 1818509..1821079(-) (hexA) [Streptococcus equinus strain NM-2-29]
MAKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTAVDSTKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFYATSLSDFAS
LKSEILNLKAREIVVGYELSEEEKHSLVKQLNLLLSFEQERFEDVHLIDSNLASLEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNREQIEERQNIIQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLGQVPTIKAILESFESPYLDKLVNSIDTLPELESLISSAIDP
DAQAVITEGSIIKTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRAQVERYISRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFGRNTNIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVSLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TTLSTTLTHLVNVHVATLERNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEDLLQRADSILTNLESGAAQLHLTPEVDSE
PLATESEVSEPVAEQLSLFAEDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=988949 ACNR93_RS08930 WP_420543623.1 1818509..1821079(-) (hexA) [Streptococcus equinus strain NM-2-29]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTTAAAAAAGACTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGATTTTTACGAATTATTTTACGATGATGCAGTTAAGGCTGCACAGATTTTAGAGATTAGTTTGACTAGTC
GAAATAAAAACGCTGAAAATCCTATTCCAATGGCAGGGGTACCATATCACTCAGCTCAGCAATATATTGATGTCCTTGTT
GAAATGGGCTACAAAGTTGCGATTGCAGAACAAATGGAAGATCCCAAGAAAGCAGTCGGTGTTGTAAAACGTGAAGTTGT
TCAAGTCATTACGCCAGGTACGGCAGTTGATTCGACAAAACCTGACAATGCCAATAATTTCTTGGTGGCTATTGATTCTG
ATGGCAAGACTTTTGGTCTAGCTTACATGGATGTGTCGACAGGTGAGTTTTATGCGACAAGTCTGTCAGATTTTGCCAGT
CTTAAAAGTGAAATCCTAAACCTTAAAGCACGTGAGATTGTTGTTGGCTACGAACTTTCAGAAGAAGAAAAACACAGTCT
TGTTAAACAACTCAACTTGCTTTTATCGTTTGAACAAGAGCGTTTTGAAGATGTACACTTGATTGATTCTAATTTGGCCT
CTTTGGAGATTTCAGCTGCTGAGAAATTACTACAGTACGTCCATACCACTCAAAAACGTGAGCTCAGCCATTTGCAAAAA
TTGGTTCACTATGAAATCAAAGATTATCTTCAAATGTCTTATACGACAAAATCAAGTCTTGATTTATTAGAAAATGCACG
TACAAGCAAGAAACACGGTAGTCTTTATTGGTTACTTGATGAGACAAAGACAGCTATGGGGATGCGTCTTTTGCGCAATT
GGATCGACCGTCCTTTGGTTAATCGAGAACAAATCGAAGAACGTCAAAATATCATTCAAGTTTTCTTAGACAATTTCTTT
GAGCGTAGTGATTTGACAGATAGTCTTAAGGGTGTTTATGATATTGAACGCTTGGCGAGTCGTGTGTCATTTGGTAAGGC
TAATCCAAAAGACCTTCTTCAACTTGGTCATACTTTGGGGCAAGTGCCTACTATCAAGGCTATTTTGGAATCCTTTGAAA
GTCCATACCTTGACAAACTTGTCAACAGCATTGACACTCTTCCTGAGTTGGAATCATTGATTAGCTCTGCTATTGACCCA
GATGCTCAAGCTGTTATCACAGAAGGTAGCATCATTAAAACTGGTTTTGATGAGACTTTGGATAAATACCGCAAAGTCAT
GCGTGAAGGCACAAGCTGGATTGCTGAGATTGAAGCTAAAGAACGTGCCGCAAGTGGTATTACAAATCTAAAAATTGATT
ACAATAAAAAAGATGGCTATTATTTCCATGTCACAAATTCTAACCTTTCTTTAGTACCAGATTATTTCTTCCGTAAAGCA
ACTTTGAAGAATTCAGAACGTTTTGGTACGGCAGAACTGGCTAAAATTGAAGGTGAAATGTTAGAAGCGCGTGAACAATC
AGCGAGCCTAGAATACGATATTTTCATGCGTGTTCGTGCGCAGGTTGAACGTTATATTTCACGTTTGCAAGACTTGGCAA
AAGCCATTTCAACAGTCGATGTTTTGCAAAGTTTAGCTGTGGTTGCTGAAAACAATCATTATGTGCGTCCAACTTTCAAT
GATAGCCATGAGATTAAGATTGAAAAAGGTCGTCACGCAGTCGTTGAAAAAGTCATGGGAACTCAGGAATATATTCCAAA
TACGATTACATTTGGTAGAAATACTAATATTCAGCTGATTACTGGTCCTAATATGAGTGGTAAGTCAACGTATATGCGTC
AGCTAGCATTGACTGTTATCATGGCACAAATGGGGTCTTATGTCGCTGCTGAAAGTGTCAGCCTACCAGTCTTCGATGCT
ATTTTCACACGTATTGGTGCAGCTGATGACTTGATTTCAGGTCAGTCAACCTTCATGGTAGAAATGATGGAAGCTAACCA
AGCTATTAAACGTGCTAGTGATAAGTCTTTGATTCTCTTTGATGAATTGGGACGTGGTACGGCTACCTATGATGGTATGG
CTTTGGCACAATCTATTATTGAGTATATTCACGACCATATTGGGGCTAAAACGATGTTTGCAACACACTATCATGAATTG
ACAACTCTGTCAACGACGTTGACACACCTTGTCAACGTCCATGTTGCAACCCTTGAACGTAATGGTGATGTGACTTTCCT
TCACAAGATTGCAGAAGGACCAGCTGATAAATCCTATGGTATTCACGTTGCAAAAATTGCAGGCCTACCAGAAGACTTAT
TGCAGCGTGCAGACAGCATTTTAACTAATCTTGAATCAGGTGCTGCGCAGCTTCATTTGACACCAGAAGTTGACAGTGAA
CCATTAGCAACTGAGTCAGAAGTTTCAGAACCTGTAGCGGAGCAATTAAGTCTTTTTGCAGAAGATTCTTCTAATCAAGA
AGTGATTGAAGCACTTAAGAAAGTTGATTTGATGAACTTGACACCTATGCAGGCTATGAATGTCATCTATGAATTGAAAA
ATATGTTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.196	100	0.722
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382