Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ACNR93_RS08925 Genome accession   NZ_CP184736
Coordinates   1816452..1818395 (-) Length   647 a.a.
NCBI ID   WP_420543622.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1811452..1823395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS08905 (ACNR93_08905) cinA 1812573..1813832 (-) 1260 WP_420543620.1 competence/damage-inducible protein A Machinery gene
  ACNR93_RS08910 (ACNR93_08910) - 1813946..1815148 (-) 1203 WP_420543621.1 MFS transporter -
  ACNR93_RS08915 (ACNR93_08915) - 1815271..1815828 (-) 558 WP_198362632.1 DNA-3-methyladenine glycosylase I -
  ACNR93_RS08920 (ACNR93_08920) ruvA 1815858..1816451 (-) 594 WP_024344431.1 Holliday junction branch migration protein RuvA Machinery gene
  ACNR93_RS08925 (ACNR93_08925) hexB 1816452..1818395 (-) 1944 WP_420543622.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACNR93_RS08930 (ACNR93_08930) hexA 1818509..1821079 (-) 2571 WP_420543623.1 DNA mismatch repair protein MutS Machinery gene
  ACNR93_RS08935 (ACNR93_08935) - 1821066..1821419 (-) 354 WP_027968295.1 YlbF family regulator -
  ACNR93_RS08940 (ACNR93_08940) argR 1821416..1821853 (-) 438 WP_021143308.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72949.15 Da        Isoelectric Point: 5.3720

>NTDB_id=988948 ACNR93_RS08925 WP_420543622.1 1816452..1818395(-) (hexB) [Streptococcus equinus strain NM-2-29]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEESGLKKIQVTDNGEGIAQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFMVKTATADENYGTLLIAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMTLISS
AIAESLRAQDLIPDALENLAKSSTRGLPKPEQTSLPLKQSNLYYDKERHDFFVKSDTVEERPVQLFNEVDTPVKEVDKQS
SVKYAQRSTQGNLADGEHDDLDFKNKSKINKLLENLDGEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKY
EYYRDKIGDVDASLQQLLMPYLFEFSGADFIKLQEKMELLNQVGINLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARQLLVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=988948 ACNR93_RS08925 WP_420543622.1 1816452..1818395(-) (hexB) [Streptococcus equinus strain NM-2-29]
ATGAGTAAAATTATCGAGTTACCAGAGGTTCTAGCCAATCAAATTGCTGCTGGTGAGGTTATTGAACGCCCGGCTAGCGT
GGTCAAGGAATTAGTAGAAAATTCGATTGATGCTGGAAGCAGTCAGATTACTATTGAAATTGAAGAGTCTGGTTTGAAAA
AAATCCAAGTTACTGATAACGGTGAGGGAATTGCTCAAGAGGATGTTGCTCTTAGTTTGCACCGTCACGCGACTAGTAAA
ATTAAAAGTCAAGCCGACCTGTTTCGAATCAGAACGCTTGGTTTCCGTGGCGAAGCCATTCCTTCCATCGCTTCAATCAG
TCATTTTATGGTGAAAACAGCAACGGCTGATGAAAATTATGGGACGCTTTTGATTGCTAAGGGTGGCGAAATTGAAAAAC
AAGAGCCAATCTCAACGCCCGTTGGAACAAAAATTACAGTTGAAAATCTGTTTTACAACACACCAGCTCGTCTTAAGTAT
ATGAAGAGTCTACAGTCAGAGTTGGCACATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCTGAAATTGCCTT
CACTTTGATTAATGATGGACGTCAGATGACAACGACATCAGGTACTGGAGATTTGCGCCAAGCGATTGCTGGGATTTATG
GCTTAAACACAGCTAAGAAGATGATTGAGATTTCAAATGCAGATCTTGATTTTGAGGTATCAGGTTACATTAGTTTACCT
GAATTGACGCGTGCGAATCGCAATTATATTACGATTTTGATTAACGGACGTTACATCAAAAATTTCTTACTGAATCGTGC
CATCTTGGACGGTTATGGTTCAAAATTGATGGTTGGTCGTTTCCCGATTGCTGTCATTGATATCCAGATTGACCCGTATC
TTGCTGATGTCAATGTTCACCCAACAAAGCAAGAAGTTCGTATCTCAAAAGAAAAGGAATTGATGACTCTCATCAGCTCA
GCTATTGCAGAGAGTTTACGTGCTCAGGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGCACTCGTGGCTT
GCCTAAACCAGAGCAAACGAGCCTGCCCTTAAAACAATCAAATCTTTATTATGACAAAGAGCGACACGATTTCTTTGTGA
AATCAGATACTGTTGAAGAGCGGCCTGTTCAGCTGTTTAATGAGGTTGACACACCTGTCAAGGAAGTTGACAAGCAGTCT
TCAGTCAAATACGCACAGCGTTCTACTCAGGGAAACCTTGCAGACGGCGAGCATGATGACCTTGATTTCAAAAATAAATC
TAAAATTAATAAGTTGCTCGAAAATCTTGATGGTGAAGAATCATCAACTTTCCCTGAACTTGATTATTTTGGTCAGATGC
ATGGGACATATCTTTTTGCGCAGGGAAATGGTGGCCTTTATATCATTGACCAACATGCGGCGCAGGAACGTGTTAAATAT
GAATATTATCGTGACAAAATTGGTGATGTCGATGCCTCACTTCAACAATTGCTCATGCCATATTTGTTTGAGTTTTCTGG
AGCAGATTTTATCAAGCTTCAAGAAAAAATGGAGCTTTTAAATCAAGTTGGCATCAATCTAGAACCATATGGGAACAATA
CATTTATTCTTCGTGAACATCCTATTTGGATGAAAGAAGAGGAGATTGAATCGGCTGTTTATGAAATGTGTGACATGTTG
CTTTTGACGAATGAAGTATCTGTCAAAAAATACCGTGCAGAGTTAGCGATTATGATGTCATGTAAACGTTCAATCAAAGC
TAATCACACTCTTGATGATTATTCAGCACGTCAACTTCTAGTGCAATTATCACAATGTAAGAATCCGTATAATTGTCCAC
ACGGTCGTCCTGTCCTGGTCAATTTTACTAAATCAGACATGGAAAAGATGTTCCGTCGTATTCAAGAAAATCATACAAGT
TTAAGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(449-591)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.579

100

0.716

Multiple sequence alignment