Detailed information NTG0988626

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: AAC934_RS13150
• Genome accession: NZ_CP152362
• Coordinates: 2559764..2560381 (-)
• Length: 205 a.a.
• NCBI ID: WP_004398514.1
• Uniprot ID: A0AAE2SLR2
• Organism: Bacillus subtilis strain LP
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2554764..2565381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAC934_RS13120 (AAC934_13120)	rpsT	2555073..2555339 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
AAC934_RS13125 (AAC934_13125)	holA	2555354..2556397 (-)	1044	WP_015714286.1	DNA polymerase III subunit delta	-
AAC934_RS13130 (AAC934_13130)	-	2556437..2556586 (-)	150	WP_003229985.1	hypothetical protein	-
AAC934_RS13135 (AAC934_13135)	yqzM	2556627..2556761 (+)	135	WP_003229983.1	YqzM family protein	-
AAC934_RS13140 (AAC934_13140)	comEC	2556801..2559131 (-)	2331	WP_074794436.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAC934_RS13145 (AAC934_13145)	comEB	2559128..2559697 (-)	570	WP_015714288.1	ComE operon protein 2	-
AAC934_RS13150 (AAC934_13150)	comEA	2559764..2560381 (-)	618	WP_004398514.1	competence protein ComEA	Machinery gene
AAC934_RS13155 (AAC934_13155)	comER	2560465..2561286 (+)	822	WP_015714289.1	late competence protein ComER	-
AAC934_RS13160 (AAC934_13160)	yqeM	2561352..2562095 (-)	744	WP_069322765.1	class I SAM-dependent methyltransferase	-
AAC934_RS13165 (AAC934_13165)	rsfS	2562092..2562448 (-)	357	WP_041333759.1	ribosome silencing factor	-
AAC934_RS13170 (AAC934_13170)	yqeK	2562466..2563026 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
AAC934_RS13175 (AAC934_13175)	nadD	2563016..2563585 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
AAC934_RS13180 (AAC934_13180)	yhbY	2563597..2563887 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
AAC934_RS13185 (AAC934_13185)	aroE	2563881..2564723 (-)	843	WP_003229967.1	shikimate dehydrogenase	-

Sequence

Protein

• Length: 205 a.a.
• Molecular weight: 21769.45 Da
• Isoelectric Point: 4.7220

>NTDB_id=988626 AAC934_RS13150 WP_004398514.1 2559764..2560381(-) (comEA) [Bacillus subtilis strain LP]
MNWLNQHKKAIILAASAAVFTAIMIFLATGKNKEPVKQAVPTETENTVVKQEANNDESNETIVIDIKGAVQHPGVYEMRT
GDRVSQAIEKAGGTSEQADEAQVNLAEILQDGTVVYIPKKGEETAVQQGGGGSVQSDGGKGALVNINTATLEELQGISGV
GPSKAEAIIAYREENGRFQTIEDITKVSGIGEKSFEKIKSSITVK

Nucleotide

• Length: 618 bp

>NTDB_id=988626 AAC934_RS13150 WP_004398514.1 2559764..2560381(-) (comEA) [Bacillus subtilis strain LP]
ATGAATTGGTTGAATCAGCATAAGAAAGCAATTATTTTAGCGGCTTCTGCGGCTGTTTTCACAGCGATTATGATCTTTCT
GGCCACAGGGAAAAATAAAGAGCCGGTGAAGCAAGCTGTACCAACAGAGACAGAAAATACAGTGGTAAAGCAGGAAGCAA
ACAACGACGAGTCAAACGAAACAATTGTGATAGACATCAAAGGTGCTGTTCAGCATCCTGGCGTTTATGAAATGCGAACA
GGGGACAGAGTATCTCAGGCAATTGAGAAAGCGGGCGGGACCAGTGAACAAGCAGACGAAGCGCAAGTAAATTTGGCGGA
GATTCTGCAGGACGGGACAGTGGTGTACATCCCGAAAAAGGGAGAGGAAACAGCAGTGCAGCAAGGTGGCGGAGGGTCTG
TCCAAAGCGATGGAGGGAAGGGAGCGCTGGTGAATATCAATACAGCAACCTTAGAGGAGTTACAAGGCATCTCAGGGGTG
GGGCCATCCAAAGCTGAAGCTATTATTGCATACCGGGAAGAAAACGGTCGTTTCCAAACAATTGAAGATATCACTAAGGT
TTCAGGAATAGGTGAAAAGTCATTTGAGAAAATAAAGTCTTCCATTACAGTAAAGTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (142-203)

• SLBB domain (SLBB) (63-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	100	100	1
comEA	Staphylococcus aureus MW2	37.273	100	0.4
comEA	Staphylococcus aureus N315	36.364	100	0.39